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company name :
Rockland Immunochemicals
product type :
antibody
product name :
CD40 Allophycocyanin Antibody
catalog :
200-326-N67
quantity :
500 µL
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
5C3
reactivity :
human
application :
flow cytometry
more info or order :
product information
Catalog Number :
200-326-N67
Name :
Anti-CD40 (MOUSE) Allophycocyanin Conjugated Monoclonal Antibody - 200-326-N67
Display Name :
CD40 Allophycocyanin Antibody
Application Note :
Anti-CD40 is useful for Flow Cytometry. Researchers should determine optimal titers for applications that are not stated.
Buffer :
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Clonality :
Monoclonal
Clone ID :
5C3
Concentration Definition :
Sufficient to run approximately 100 tests
Conjugation :
APC
Size :
500 µL
Default Unit :
ul
Flow Cytometry Dilution :
5 uL/test/1x10e5 to 1x10e8 cells
Fluorochrome Protein Value :
1-2
Expiration :
Expiration date is six (6) months from date of opening.
Format :
IgG1
Gene Name :
CD40
Host Animal :
Mouse
General Disclaimer Note :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
Immunogen :
Anti-CD40 Antibody (Monoclonal) was produced by repeated immunizations with CD40 antigen.
Packing Type :
Wet Ice
Physical State :
Liquid (sterile filtered)
Preservative :
0.09% (w/v) Sodium Azide
Purity and Specificity :
Allophycocyanin conjugated CD40 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD40. Reactivity is observed against human CD40. Cross reactivity is observed with Baboon, Chimpanzee, Cynomolgus Monkey, Rhesus, and Squirrel Monkey. Reactivity with CD40 from other sources has not been tested. Anti-CD40 is conjugated with APC under optimal conditions and the solution is free of unconjugated APC.
Species Reactivity :
Human
Stabilizer :
0.2% BSA (w/v)
Storage :
Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
Subclass :
IgG1 kappa
Synonyms :
BP50, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40
Target Species :
Human
Background :
CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.
Low Endotoxin :
No
Sample Size :
No
Application Text :
Flow Cytometry,
Category :
Primary Antibodies
Conjugation Name :
Allophycocyanine
UniProt :
P25942
NCBI :
NP_001241.1
Primary Image Name :
Flow Cytometry of Mouse anti-CD40 APC - 200-326-N67
more info or order :
company information

Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
Pottstown, PA 19464
tech@rockland.com
https://www.rockland.com/484-791-3823
headquarters: USA
Rockland Immunochemicals, Inc. produces Phosho-Site Specific Antibodies and Antibody based tools for basic, applied and clinical research. Our laboratory is located west of Philadelphia, Pennsylvania, USA. The technology base of the organization is the experience of its staff scientists in the production and purification of a wide range of antibodies through monoclonal & polyclonal antibody techniques utilizing in vitro and in vivo methods. Rockland's antibodies are suited for individuals performing Western Blotting, ELISA, Immunohistochemistry, Fluorescent Microscopy, High Content Screening and diagnostic kit production. Primary antibodies include Akt Pathway, Apolipoproteins, Apoptosis/Cell Cycle, Cytokines, Cell Signaling, Enzymes, Extracellular Matrix, Transcription Factors (NFkB) and Ubiquitin.
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