FIG4/SAC3 Antibody Peroxidase | Rockland Immunochemicals 200-303-W80 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

FIG4/SAC3 Antibody Peroxidase

catalog :

200-303-W80

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

HRP

clone name :

S202-7

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-303-W80

Name :

Anti-FIG4/SAC3 (MOUSE) Monoclonal Antibody Peroxidase Conjugated - 200-303-W80

Display Name :

FIG4/SAC3 Antibody Peroxidase

Application Note :

Anti-FIG4/SAC3 HRP Conjugated Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~100kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

S202-7

Concentration Value :

1mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

HRP

Size :

100 µg

Default Unit :

µg

ELISA Dilution :

1:10,000

Immunohistochemistry Dilution :

User Optimized

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG1

Gene Name :

Fig4

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-FIG4/SAC3 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 688-907 of mouse Sac3.

Packing Type :

Wet Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.1% (w/v) Sodium Azide

Purity and Specificity :

Anti-FIG4/SAC3 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests that it is 95% identical to rat and 91% identical to human.

Species Reactivity :

Human, Rat, Mouse

Stabilizer :

50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG1

Synonyms :

Polyphosphoinositide phosphatase, 5-bisphosphate 5-phosphatase, Fig4, KIAA0274, Sac3, Phosphatidylinositol 3, Phosphatidylinositol 3,5 bisphosphate 5 phosphatase, SAC domain containing protein 3, SAC domain-containing protein 3, SAC3 antibody

Target Species :

Mouse

Background :

Fig4/Sac3 phosphatase, a 97-kDa protein, specifically removes the 5-phosphate from the inositol ring of PI(3,5)P2, a membrane-bound phospholipid, which acts as a molecular signal for trafficking and fusion of intracellular vesicles. It is broadly expressed in all eukaryotic cells and plays a vital role in intracellular membrane trafficking and signaling. Mutations in Fig4/Sac3 have been linked to pale tremor mice that exhibit neuropathy with severe central and peripheral neuronal degeneration, including the loss of neurons in the dorsal root ganglion and the sciatic nerve. Fig4/Sac3 knockout mice have been shown to be smaller in size and exhibit abnormal tremor and gait and neuronal autophagy. Anti-Fig4/Sac3 is ideal for research in Neuroscience and Cell Signaling.

Immunogen Type :

Recombinant Protein

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

C-Terminus

Application Text :

ELISA,Immunohistochemistry,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Peroxidase (Horseradish)

UniProt :

Q91WF7

more info or order :

Rockland Immunochemicals product webpage