Laforin Antibody Peroxidase | Rockland Immunochemicals 200-303-W78 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Laforin Antibody Peroxidase

catalog :

200-303-W78

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

HRP

clone name :

S84-37

reactivity :

human

application :

western blot, ELISA

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-303-W78

Name :

Anti-Laforin (MOUSE) Monoclonal Antibody Peroxidase Conjugated - 200-303-W78

Display Name :

Laforin Antibody Peroxidase

Application Note :

Anti-Laforin HRP Conjugated Antibody is suitable for Western Blots and Immunocytochemistry. Expect a band approximately ~40kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

S84-37

Concentration Value :

1mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

HRP

Size :

100 µg

Default Unit :

µg

ELISA Dilution :

1:10,000

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG1

Gene Name :

EPM2A

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-Laforin Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 1-331 (full length) of human Laforin.

Packing Type :

Wet Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.1% (w/v) Sodium Azide

Purity and Specificity :

Anti-Laforin Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests that it is 90% identical to rat and 89% identical to human.

Species Reactivity :

Human

Stabilizer :

50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG1

Synonyms :

EPM2, Epilepsy progressive myoclonus type 2 Lafora disease (laforin) , Epilepsy progressive myoclonus type 2A Lafora disease (laforin), EPM2 antibody, Epm2a antibody, Lafora PTPase, LAFPTPase, LD antibody, LDE antibody, MELF antibody, Glucan phosphatase, Glycogen phosphatase, EPM2A

Target Species :

Human

Background :

Laforin, also known as Lafora PTPase, is a dual specificity protein phosphatase. Laforin is involved in the control of glycogen metabolism, specifically in preventing the formation of poorly branched glycogen molecules (polyglucosans). Laforin forms a complex with NHLRC1/malin and HSP70 that suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system (UPS). Laforin is expressed in heart, skeletal muscle, kidney, pancreas and brain. Defective Laforin is linked to progressive myoclonic epilepsy type 2 (EPM2). Anti-Laforin is ideal for research in Neuroscience, Cell Signaling and Metabolic Processes.

Immunogen Type :

Recombinant Protein

Low Endotoxin :

Sample Size :

Application Text :

ELISA,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Peroxidase (Horseradish)

UniProt :

O95278

more info or order :

Rockland Immunochemicals product webpage