CD11c Fluorescein Antibody | Rockland Immunochemicals 200-302-N63 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

CD11c Fluorescein Antibody

catalog :

200-302-N63

quantity :

500 µL

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

3.9

reactivity :

human

application :

immunohistochemistry, flow cytometry

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-302-N63

Name :

Anti-CD11c (MOUSE) Fluorescein Conjugated Monoclonal Antibody - 200-302-N63

Display Name :

CD11c Fluorescein Antibody

Application Note :

Anti-CD11c is useful for Flow Cytometry and Immunohistochemistry. Researchers should determine optimal titers for applications that are not stated.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

3.9

Concentration Definition :

Sufficient to run approximately 100 tests

Conjugation :

FITC

Size :

500 µL

Default Unit :

Flow Cytometry Dilution :

5 ul/1x10e6 cells or 100µL of whole blood

Fluorochrome Protein Value :

4-6

Immunohistochemistry Dilution :

User Optimized

Expiration :

Expiration date is six (6) months from date of opening.

Format :

IgG1

Gene Name :

ITGAX

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-CD11c Antibody (Monoclonal) was produced by repeated immunizations with CD11c antigen.

Packing Type :

Wet Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.09% (w/v) Sodium Azide

Purity and Specificity :

Fluorescein conjugated CD11c Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD11c. Reactivity is observed against human CD11c, Chimpanzee, Baboon, African Green, Cynomolgus, Rhesus, and Squirrel Monkey. Cross reactivity with CD11c from other sources has not been tested. Anti-CD11c is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC.

Species Reactivity :

Human

Stabilizer :

0.2% BSA (w/v)

Storage :

Store vial at 4° C prior to opening. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. DO NOT FREEZE. This product is light sensitive.

Subclass :

IgG1 kappa

Synonyms :

Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150 95, CD11c

Target Species :

Human

Background :

CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTThe 3.9 antibody reacts with human CD11c, also known as integrin alpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

Low Endotoxin :

Sample Size :

Application Text :

Flow Cytometry,Immunohistochemistry,

Category :

Primary Antibodies

Conjugation Name :

Fluorescein (FITC)

UniProt :

P20702

NCBI :

NP_000878.2

Primary Image Name :

Flow Cytometry - Mouse anti-CD11c FITC

more info or order :

Rockland Immunochemicals product webpage