HDAC3 Antibody | Rockland Immunochemicals 200-301-V03 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

HDAC3 Antibody

catalog :

200-301-V03

quantity :

50 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

application :

chromatin immunoprecipitation

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-301-V03

Name :

Anti-HDAC3 (MOUSE) Monoclonal Antibody - 200-301-V03

Display Name :

HDAC3 Antibody

Application Note :

Anti-HDAC3 Antibody is suitable for Chromatin Immunoprecipitation and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 48.8 kDa in the appropriate cell lysate or extract.

Buffer :

0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Concentration Value :

2 mg/ml

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

50 µg

Default Unit :

µg

ChIP Dilution :

2 μg/ChIP

IF Microscopy Dilution :

1:500

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG1

Gene Name :

HDAC3

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-HDAC3 Antibody was produced in mice by repeated immunization with a synthetic peptide containing a sequence from the C-terminal region of the human HDAC3 protein.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.05% (w/v) Sodium Azide and 0.05% ProClin 300

Purity and Specificity :

Anti-HDAC3 Antibody was purified by Protein A chromatography. Cross-reactivity with HDAC3 from other sources has not been determined.

Species Reactivity :

Human

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG1

Synonyms :

HD3, RPD3-2, SMAP45

Target Species :

Human

Background :

HDAC3 catalyses the deacetylation of lysine residues in the N-terminal part of the core histones (H2A, H2B, H3 and H4). Acetylation and deacetylation of these highly conserved lysine residues is important for the control of gene expression and HDAC activity is associated with gene repression. Histone deacetylation is established by the formation of large multiprotein complexes. HDAC3 may bind to the zinc-finger transcription factor YY1, thereby regulating transcription. It is also able to modulate cell growth and apoptosis through the interaction with p53 and is thought to be essential for the repression of the POU1F1 transcription factor. Anti-HDAC3 Antibody is ideal for research in Epigenetics and Gene Expression.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

C-Terminus

Application Text :

Chip,IF Microscopy,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

O15379

NCBI :

NP_003874.2

Primary Image Name :

Immunofluorescence Microscopy of anti-HDAC3 antibody

more info or order :

Rockland Immunochemicals product webpage