product summary
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company name :
Rockland Immunochemicals
product type :
antibody
product name :
Spectrin (alpha and beta) Antibody
catalog :
200-301-P46
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Spe 1/2
reactivity :
human
application :
western blot, ELISA
product information
Catalog Number :
200-301-P46
Name :
Anti-Spectrin (alpha and beta) (MOUSE) Antibody - 200-301-P46
Display Name :
Spectrin (alpha and beta) Antibody
Application Note :
Anti-Spectrin is useful for Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~246-280 kDa corresponding to the appropriate cell lysate or extract.
Buffer :
1.2% sodium acetate
Clonality :
Monoclonal
Clone ID :
Spe 1/2
Concentration Value :
1.0 mg/mL
Concentration Definition :
by UV absorbance at 280 nm
Conjugation :
(None)
Size :
100 µg
Default Unit :
µg
ELISA Dilution :
1:40,000
Western Blot Dilution :
2-4ug/ml
Expiration :
Expiration date is one (1) year from date of opening.
Format :
IgG1
Gene Name :
SPTA1/SPTB
Host Animal :
Mouse
General Disclaimer Note :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
Immunogen :
Spectrin(alpha and beta) antibody was produced in mice by repeated immunizations with human erythrocyte spectrin.
Packing Type :
Ambient
Physical State :
Lyophilized
Preservative :
0.01% (w/v) Sodium Azide
Purity and Specificity :
Anti-Spectrin antibody was purified from mouse ascites by protein A chromatography.  This product reacts with human. Cross reactivity with Spectrin from other sources has not been determined.
Reconstitution Buffer :
Neutral PBS
Reconstitution Volume :
1.0 mL
Species Reactivity :
Human
Stabilizer :
2mg BSA
Storage :
Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Subclass :
IgG1
Synonyms :
EL2, HPP, HS3, SPH3, SPTA, SPTA1, EL3, HS2, SPH2, HSPTB1, Erythroid alpha-spectrin, Spectrin alpha chain erythrocytic 1, Spectrin beta chain erythrocytic, Beta-I spectrin, SPTB, SPTB1
Target Species :
Human
Background :
Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2. Spectrin mutations cause spinocerebellar ataxia type 5. This antibody is suitable for researchers interested in cytoskeleton and transcriptoion factor research.
Immunogen Type :
Other
Low Endotoxin :
No
Sample Size :
No
Application Text :
ELISA,Western Blot,
Category :
Primary Antibodies
Conjugation Name :
Unconjugated
UniProt :
P02549
NCBI :
NP_003117.2
company information
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
tech@rockland.com
https://www.rockland.com/
484-791-3823
headquarters: USA
Rockland Immunochemicals, Inc. produces Phosho-Site Specific Antibodies and Antibody based tools for basic, applied and clinical research. Our laboratory is located west of Philadelphia, Pennsylvania, USA. The technology base of the organization is the experience of its staff scientists in the production and purification of a wide range of antibodies through monoclonal & polyclonal antibody techniques utilizing in vitro and in vivo methods. Rockland's antibodies are suited for individuals performing Western Blotting, ELISA, Immunohistochemistry, Fluorescent Microscopy, High Content Screening and diagnostic kit production. Primary antibodies include Akt Pathway, Apolipoproteins, Apoptosis/Cell Cycle, Cytokines, Cell Signaling, Enzymes, Extracellular Matrix, Transcription Factors (NFkB) and Ubiquitin.