TRF2 Antibody | Rockland Immunochemicals 200-301-I34 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

TRF2 Antibody

catalog :

200-301-I34

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4A794.15

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-301-I34

Name :

Anti-TRF2 (MOUSE) Monoclonal Antibody - 200-301-I34

Display Name :

TRF2 Antibody

Application Note :

Anti-TRF2 Antibody is suitable for use in ChIP, ELISA, Flow (Intracellular) Cytometry, IF/ICC, IHC (frozen), IP, and WB. Expect a band approximately 55.6 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

4A794.15

Concentration Value :

1.0 mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µg

Default Unit :

µg

ELISA Dilution :

2 µg/mL

ChIP Dilution :

User Optimized

Flow Cytometry Dilution :

User Optimized

Immunohistochemistry Dilution :

5 µg/mL

IF Microscopy Dilution :

User Optimized

Immunoprecipitation Dilution :

2 µg/10^6 cells

Western Blot Dilution :

2-4 µg/mL

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG1

Gene Name :

TERF2

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

TRF2 Antibody was produced in mice by repeated immunizations with a full-length TRF2 human protein.

Packing Type :

Dry Ice

Physical State :

Liquid

Preservative :

0.05% (w/v) Sodium Azide

Purity and Specificity :

Anti-TRF2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TRF2 from Human, Mouse, Muntjac (deer), and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TRF2 from other sources has not been determined.

Species Reactivity :

Human

Stabilizer :

0.05% BSA

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG1 kappa

Synonyms :

TRBF2, TRF2, Telomeric repeat-binding factor 2, TTAGGG repeat-binding factor 2, Telomeric DNA-binding protein

Target Species :

Human

Background :

TRF2 antibody detects human, mouse, deer and rat TRF2. TRF2 is an ubiquitously expressed protein that is implicated in the control of telomere length. TRF2, like TRF1, contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes. TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini. The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells. Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types. Anti TRF2 antibody is ideal for investigators involved in apoptosis and chromatin research.

Immunogen Type :

Recombinant Protein

Low Endotoxin :

Sample Size :

Application Text :

ELISA,Chip,Flow Cytometry,Immunohistochemistry,IF Microscopy,Immunoprecipitation,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

Q15554

NCBI :

NP_005643

Primary Image Name :

TRF2 Immunofluorescence

more info or order :

Rockland Immunochemicals product webpage