product summary
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company name :
Rockland Immunochemicals
product type :
antibody
product name :
WAVE1-Scar Antibody
catalog :
200-301-G64
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S91-36
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation
product information
Catalog Number :
200-301-G64
Name :
Anti-WAVE1-Scar (MOUSE) Monoclonal Antibody - 200-301-G64
Display Name :
WAVE1-Scar Antibody
Application Note :
Anti-WAVE1-Scar Antibody is suitable for use in WB, IHC and IP. Expect a band approximately 75kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Buffer :
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Clonality :
Monoclonal
Clone ID :
S91-36
Concentration Value :
1 mg/mL
Concentration Definition :
by UV absorbance at 280 nm
Conjugation :
(None)
Size :
100 µg
Default Unit :
µg
Immunohistochemistry Dilution :
0.1-1.0ug/mL
IF Microscopy Dilution :
1.0-10ug/mL
Immunoprecipitation Dilution :
User Optimized
Western Blot Dilution :
1ug/mL
Expiration :
Expiration date is one (1) year from date of opening.
Format :
IgG1
Gene Name :
WASF1
Host Animal :
Mouse
General Disclaimer Note :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
Immunogen :
WAVE1-Scar Antibody was produced in mice by repeated immunizations raised against a synthetic peptide corresponding to the near c-terminal region of human Wave1/Wasp family1.
Packing Type :
Dry Ice
Physical State :
Liquid (sterile filtered)
Preservative :
0.09% (w/v) Sodium Azide
Purity and Specificity :
Anti-WAVE1-Scar Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with WAVE1-Scar from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with WAVE1-Scar from other sources has not been determined. Neuroscience research.
Species Reactivity :
Human, Mouse, Rat
Stabilizer :
50% (v/v) Glycerol
Storage :
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Subclass :
IgG1
Synonyms :
Wave1, Scar1, WASP, Wave, WASF1, Wiskott-Aldrich syndrome protein family member 1, WASP family protein member 1, Verprolin homology domain-containing protein 1
Target Species :
Human
Background :
The Wiskott-Aldrich syndrome protein (WASP) family plays essential roles in the regulation of actin polymerization. There are five WASP family members: Wasp, N-WASP, Wave1 (WASP family verprolin-homologous protein 1), WAVE2 and WAVE3. The Wasp family proteins share a conserved C-terminal region called the verprolin homology, cofilin homology and acidic domain. The Wave/Scar family of prtoteins mediates signals to actin assembly by direct activation of the Arp2/3 complex. These proteins have been characterized as major regulators of lamellipodia formation downstream of Rac activation, and as members of large protein complexes. IT has been found that all three Scar/Wave isoforms behave similarily and are likely to participate in the same kinds of protein complexes.
Immunogen Type :
Peptide
Low Endotoxin :
No
Sample Size :
No
Target Domain of Reactivity :
C-Terminus
Application Text :
Immunohistochemistry,IF Microscopy,Immunoprecipitation,Western Blot,
Category :
Primary Antibodies
Conjugation Name :
Unconjugated
UniProt :
Q92558
NCBI :
NP_001020105.1
company information
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
tech@rockland.com
https://www.rockland.com/
484-791-3823
headquarters: USA
Rockland Immunochemicals, Inc. produces Phosho-Site Specific Antibodies and Antibody based tools for basic, applied and clinical research. Our laboratory is located west of Philadelphia, Pennsylvania, USA. The technology base of the organization is the experience of its staff scientists in the production and purification of a wide range of antibodies through monoclonal & polyclonal antibody techniques utilizing in vitro and in vivo methods. Rockland's antibodies are suited for individuals performing Western Blotting, ELISA, Immunohistochemistry, Fluorescent Microscopy, High Content Screening and diagnostic kit production. Primary antibodies include Akt Pathway, Apolipoproteins, Apoptosis/Cell Cycle, Cytokines, Cell Signaling, Enzymes, Extracellular Matrix, Transcription Factors (NFkB) and Ubiquitin.