product summary
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company name :
Rockland Immunochemicals
product type :
antibody
product name :
Sodium-Iodide Symporter Antibody
catalog :
200-301-G49
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
14F
reactivity :
human, mouse, rat
application :
western blot
product information
Catalog Number :
200-301-G49
Name :
Anti-Sodium-Iodide Symporter (MOUSE) Monoclonal Antibody - 200-301-G49
Display Name :
Sodium-Iodide Symporter Antibody
Application Note :
Anti-Sodium-Iodide Symporter Antibody is suitable for use in WB. Expect a band approximately 97kD, non-glycosylated version at 68kD. Other minor bands associated with hNIS at 160 kDa, and degradation products at ~30 kDa, and ~15kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Buffer :
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Clonality :
Monoclonal
Clone ID :
14F
Concentration Value :
1mg/mL
Concentration Definition :
by UV absorbance at 280 nm
Conjugation :
(None)
Size :
100 µg
Default Unit :
µg
Western Blot Dilution :
1:1000
Expiration :
Expiration date is one (1) year from date of opening.
Format :
IgG1
Gene Name :
SLC5A5
Host Animal :
Mouse
General Disclaimer Note :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
Immunogen :
Sodium-Iodide Symporter Antibody was produced in mice by repeated immunizations raised against mannose binding protein hNIS fusion.
Packing Type :
Dry Ice
Physical State :
Liquid (sterile filtered)
Purity and Specificity :
Anti-Sodium-Iodide Symporter Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Sodium-Iodide Symporter from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Recognizes both rod and cone alpha subunits. Cross-reactivity with Sodium-Iodide Symporter from other sources has not been determined. Ion Channels research.
Species Reactivity :
Human, Mouse, Rat
Stabilizer :
50% (v/v) Glycerol
Storage :
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Subclass :
IgG1
Synonyms :
NIS, SLC5A5, solute carrier family 5, Na (+)I(-) cotransporter, Sodium/iodide cotransporter,
Target Species :
Human
Background :
The sodium iodide symporter (NIS) is an ion pump that actively transports iodide across the basolateral membrane into thyroid epithelial cells. This is important step in the process of iodide organificaton and the formation of triiodothyronine and thyroxine.
Immunogen Type :
Other
Low Endotoxin :
No
Sample Size :
No
Application Text :
Western Blot,
Category :
Primary Antibodies
Conjugation Name :
Unconjugated
UniProt :
Q92911
NCBI :
NP_000444.1
company information
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
tech@rockland.com
https://www.rockland.com/
484-791-3823
headquarters: USA
Rockland Immunochemicals, Inc. produces Phosho-Site Specific Antibodies and Antibody based tools for basic, applied and clinical research. Our laboratory is located west of Philadelphia, Pennsylvania, USA. The technology base of the organization is the experience of its staff scientists in the production and purification of a wide range of antibodies through monoclonal & polyclonal antibody techniques utilizing in vitro and in vivo methods. Rockland's antibodies are suited for individuals performing Western Blotting, ELISA, Immunohistochemistry, Fluorescent Microscopy, High Content Screening and diagnostic kit production. Primary antibodies include Akt Pathway, Apolipoproteins, Apoptosis/Cell Cycle, Cytokines, Cell Signaling, Enzymes, Extracellular Matrix, Transcription Factors (NFkB) and Ubiquitin.