mSlo maxi- K+ channel Antibody | Rockland Immunochemicals 200-301-G15 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

mSlo maxi- K+ channel Antibody

catalog :

200-301-G15

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S6-60

reactivity :

human, mouse, rat, zebrafish

application :

western blot, immunohistochemistry, immunoprecipitation

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-301-G15

Name :

Anti-mSlo maxi- K+ channel (MOUSE) Monoclonal Antibody - 200-301-G15

Display Name :

mSlo maxi- K+ channel Antibody

Application Note :

Anti-mSlo maxi- K+ channel Antibody is suitable for use in WB, IP, and IHC. Expect a band approximately ~110-130kDa on specific lysates. Epitope mapped within amino acids 690-715. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

S6-60

Concentration Value :

1mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µg

Default Unit :

µg

Immunohistochemistry Dilution :

0.1-1.0ug/mL

IF Microscopy Dilution :

1.0-10ug/mL

Immunoprecipitation Dilution :

User Optimized

Western Blot Dilution :

1ug/mL

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG2a

Gene Name :

Kcnma1

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

mSlo maxi- K+ channel Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to the cytoplasmic C-terminus region of mouse Slo1.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Purity and Specificity :

Anti-mSlo maxi- K+ channel Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Slo from Mouse, Human, Rat, and Zebrafish based on 100% homology with the immunizing sequence. Cross-reactivity with Slo from other sources has not been determined. Ion Channels research.

Species Reactivity :

Mouse, Human, Rat, Zebrafish

Stabilizer :

50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG2a

Synonyms :

Slo, BKCa, Slo1, mSlo, MaxiK, mSlo1, 5730414M22Rik, Kcnma1, Calcium-activated potassium channel subunit alpha-1, BK channel, BKCA alpha, Calcium-activated potassium channel, subfamily M subunit alpha-1, K(VCA)alpha, KCa1.1, Maxi K channel, Slo-alpha, Slo1

Target Species :

Mouse

Background :

The Slo1 channel is a novel potassium channel that is regulated by both Ca2+ and voltage. It is a homolog to the pH and voltage-regulated Slo3 channel. Four distinct subunits composing the KCNMB family are known to regulate the function and expression of Slo1 channels. Slo1 has been shown to be involved in neurotransmitter release and etheanol response. It has been reported that SLO1 also has a critical role is muscles- the inactivation of the slo-1 gene in muscles leased to phenotypes similar to those cause by mutations of the dystrophin homologue dys-1.

Immunogen Type :

Recombinant Protein

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

C-Terminus

Application Text :

Immunohistochemistry,IF Microscopy,Immunoprecipitation,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

Q08460

NCBI :

NP_034740.2

Primary Image Name :

mSlo maxi K+ Channel Immunofluorescence

more info or order :

Rockland Immunochemicals product webpage