Mdc1 Antibody | Rockland Immunochemicals 200-301-G12 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Mdc1 Antibody

catalog :

200-301-G12

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

P2B11

reactivity :

human, mouse, bovine, chimpanzee

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-301-G12

Name :

Anti-Mdc1 (MOUSE) Monoclonal Antibody - 200-301-G12

Display Name :

Mdc1 Antibody

Application Note :

Anti-MDC1 Antibody is suitable for use in WB and IF microscopy. Expect a band approximately ~184kDa corresponding to specific lysates. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

P2B11

Concentration Value :

1mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µg

Default Unit :

µg

IF Microscopy Dilution :

User Optimized

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG1

Gene Name :

Mdc1

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

MDC1 Antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to mouse MDC1 at and around the N-terminus region.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Purity and Specificity :

Anti-MDC1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with MDC1 from Human, Mouse, Chimpanzee, and Bovine based on 100% homology with the immunizing sequence. This antibody recognizes MDC1 at and around the N-terminus. Cross-reactivity with MDC1 from other sources has not been determined. Oxidative Stress research.

Species Reactivity :

Mouse, Human, Chimpanzee, Bovine

Stabilizer :

50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG1

Synonyms :

Nuclear factor with BRCT domains1, mediator of DNA damage checkpoint 1, Kiaa0170

Target Species :

Mouse

Background :

MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.

Immunogen Type :

Recombinant Protein

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

N-Terminus

Application Text :

IF Microscopy,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

Q5PSV9

NCBI :

NP_001010833.2

more info or order :

Rockland Immunochemicals product webpage