KV3.1 Antibody | Rockland Immunochemicals 200-301-G01 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

KV3.1 Antibody

catalog :

200-301-G01

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S16B-8

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-301-G01

Name :

Anti-KV3.1 (MOUSE) Monoclonal Antibody - 200-301-G01

Display Name :

KV3.1 Antibody

Application Note :

Anti-KV3.2 Antibody is suitable for use in WB and IHC. Expect a band approximately ~110kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

S16B-8

Concentration Value :

1.0 mg/ml

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µg

Default Unit :

µg

Immunohistochemistry Dilution :

0.1-1.0ug/mL

IF Microscopy Dilution :

1.0-10ug/mL

Western Blot Dilution :

1-10ug/mL

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG1

Gene Name :

Kcnc1

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

KV3.1 Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to the c-terminus region of rat Kv3.1b.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.09% (w/v) Sodium Azide

Purity and Specificity :

Anti-KV3.1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with KV3.1 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with KV3.1 from other sources has not been determined. Channels and Transporters research.

Species Reactivity :

Human (weak), Mouse, Rat

Stabilizer :

50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG1

Synonyms :

Krc2 1, NGK2, KCNC1, voltage gated potassium channel subunit Kv3.1, Voltage-gated potassium channel subunit Kv4, RAW2, Potassium voltage-gated channel subfamily C member 1

Target Species :

Rat

Background :

Potassium voltage-gated channel, Shaw-related subfamily, member 1, also known as KCNC1 or Kv3.1, is a human gene. The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage- dependent potassium ion permeability of excitable membranes. Kv3.1b has been extensively tested in the auditory regions of mammals, and the decline of Kv3.1b expression appears to correlate with the functional decline in the medial olivocochlear efferent system. Other research shows potential for Kv3.1b channels to be oxygen sensors.

Immunogen Type :

Recombinant Protein

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

C-Terminus

Application Text :

Immunohistochemistry,IF Microscopy,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

P25122

NCBI :

NP_036988

Primary Image Name :

Kv3.1 Immunohistochemistry

more info or order :

Rockland Immunochemicals product webpage