Kv1.1 Antibody | Rockland Immunochemicals 200-301-F90 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Kv1.1 Antibody

catalog :

200-301-F90

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S20-78

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-301-F90

Name :

Anti-Kv1.1 (MOUSE) Monoclonal Antibody - 200-301-F90

Display Name :

Kv1.1 Antibody

Application Note :

Anti-Kv1.1 Antibody is suitable for use in WB, IP, and IHC. Expect a band approximately ~85kDa (major: Mature glycosylation), ~65kDa (minor: immature glycosylation) on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

S20-78

Concentration Value :

1.0 mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µg

Default Unit :

µg

Immunohistochemistry Dilution :

0.1-1.0µg/mL

IF Microscopy Dilution :

1.0-10ug/mL

Western Blot Dilution :

1µg/mL

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG1

Gene Name :

Kcna1

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Kv1.1 Antibody was produced in mice by repeated immunizations raised against a synthetic peptide at a cytoplasmic C-terminus of rat Kv1.1.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.09% (w/v) Sodium Azide

Purity and Specificity :

Anti-Kv1.1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Kv1.1 from Mouse, Human, and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Kv1.1 from other sources has not been determined. Ion Channels research.

Species Reactivity :

Human, Mouse, Rat

Stabilizer :

50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG1

Synonyms :

KCA1, KCNA1, MBK1, MK1, RBK1, Shak, Voltage-gated potassium channel subunit Kv1.1, Potassium voltage gated channel subfamily A member 1, RBKI, RCK1

Target Species :

Rat

Background :

Kv1.1, also known as potassium voltage-gated channel subfamily A member 1, is a shaker related voltage potassium channel that in humans is encoded by the SCNA1 gene. It is strongly expressed in a variety of neurons in adult rodents, and it appears to be involved in regulating neuronal excitability. Specifically it plays a role in several developmental processes including proliferation, migration and cell-cell adhesion. The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

C-Terminus

Application Text :

Immunohistochemistry,IF Microscopy,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

P10499

NCBI :

NP_775118.1

Primary Image Name :

Kv1.1 Immunohistochemistry

more info or order :

Rockland Immunochemicals product webpage