Cav beta 4 Antibody | Rockland Immunochemicals 200-301-F07 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Cav beta 4 Antibody

catalog :

200-301-F07

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S10-7

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-301-F07

Name :

Anti-Cav beta 4 (MOUSE) Monoclonal Antibody - 200-301-F07

Display Name :

Cav beta 4 Antibody

Application Note :

Anti-Cav Beta 4 Antibody is suitable for use in WB, IP, and IHC. Expect a band approximately ~50kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Monoclonal

Clone ID :

S10-7

Concentration Value :

1mg/mL

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µg

Default Unit :

µg

Immunohistochemistry Dilution :

0.1-1.0ug/mL

IF Microscopy Dilution :

1.0-10ug/mL

Immunoprecipitation Dilution :

User Optimized

Western Blot Dilution :

1-10ug/mL

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG1

Gene Name :

CACNB4

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Cav beta 4 Antibody was produced in mice by repeated immunizations with a synthetic peptide corresponding to a near the c-terminal region of rat CavB4.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Purity and Specificity :

Anti-Cav Beta4 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Cav Beta4 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. No cross-reactivity against rat Cab Beta1b, Cav beta2a, and Cav betas3 in transfected cells. Cross-reactivity with Cav Beta4 from other sources has not been determined. Channels and Transporters research.

Species Reactivity :

Human, Mouse, Rat

Stabilizer :

50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG1

Synonyms :

CAB4, CACNLB4, EA5, EJM, Calcium channel voltage dependent beta 4 subunit

Target Species :

Rat

Background :

This gene encodes a member of the beta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein described in this record plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

C-Terminus

Application Text :

Immunohistochemistry,IF Microscopy,Immunoprecipitation,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

O00305

NCBI :

NP_000717.2

Primary Image Name :

Cav beta 4 Western Blot

more info or order :

Rockland Immunochemicals product webpage