CASPR2 Antibody | Rockland Immunochemicals 200-301-F04 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

CASPR2 Antibody

catalog :

200-301-F04

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S67-25

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-301-F04

Name :

Anti-CASPR2 (MOUSE) Monoclonal Antibody - 200-301-F04

Display Name :

CASPR2 Antibody

Application Note :

Anti-CASPR2 Antibody is suitable for use in WB, IP, and IHC. Expect a band approximately ~180kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Buffer :

1X PBS, pH 7.4

Clonality :

Monoclonal

Clone ID :

S67-25

Concentration Value :

1.0 mg/ml

Concentration Definition :

by UV absorbance at 280 nm

Conjugation :

(None)

Size :

100 µg

Default Unit :

µg

Immunohistochemistry Dilution :

0.1-1.0ug/mL

IF Microscopy Dilution :

1.0-10ug/mL

Immunoprecipitation Dilution :

User Optimized

Western Blot Dilution :

1ug/mL

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG2a

Gene Name :

CNTNAP2

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

CASPR2 Antibody was produced in mice by repeated immunizations with a fusion protein (extracellular domain) of human CASPR2.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.09% (w/v) Sodium Azide

Purity and Specificity :

Anti-CASPR2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with CASPR2 from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. No cross reactivity to CASPR/Paranodin. Cross-reactivity with CASPR2 from other sources has not been determined. Scaffolds research.

Species Reactivity :

Human, Mouse, Rat

Stabilizer :

50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG2a

Synonyms :

Cntnap2, CNTP2, Contactin associated protein like 2, Cell recognition molecule Caspr2, CASPR2, KIAA0868

Target Species :

Human

Background :

Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. It’s role is for myelin sheath attachment along with contactin in a cis-complex (3). Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B.

Immunogen Type :

Recombinant Protein

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

Extracellular

Application Text :

Immunohistochemistry,IF Microscopy,Immunoprecipitation,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

Q9UHC6

NCBI :

NP_054860.1

Primary Image Name :

CASPR2 Immunohistochemistry

more info or order :

Rockland Immunochemicals product webpage