Synaptobrevin (VAMP) Antibody | Rockland Immunochemicals 200-301-E34 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Synaptobrevin (VAMP) Antibody

catalog :

200-301-E34

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SP10

reactivity :

human, mouse

application :

western blot, immunohistochemistry

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

200-301-E34

Name :

Anti-Synaptobrevin (VAMP) (Mouse) Monoclonal Antibody - 200-301-E34

Display Name :

Synaptobrevin (VAMP) Antibody

Application Note :

Anti-Synaptobrevin antibody is suitable for use in Western Blotting and IHC. Expect a band of approximately 16 kDa in size corresponding to the VAMP proteins in Western blot of rat brain lysate. Anti-Synaptobrevin antibody has also been demonstrated to work in immunohistochemistry on formalin fixed, vibratome sections, but does not work on paraffin sections. Specific conditions for reactivity should be optimized by the end user. Researchers should determine optimal titers for applications that are not stated below.

Buffer :

0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Clonality :

Monoclonal

Clone ID :

SP10

Concentration Value :

Titrated value sufficient to run approximately 10 mini blots.

Conjugation :

(None)

Size :

100 µL

Default Unit :

Immunohistochemistry Dilution :

1:100

Western Blot Dilution :

1:1000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgM

Gene Name :

VAMP1/2

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-Synaptobrevin (VAMP) Monoclonal Antibody was produced in mouse by repeated immunizations with synaptic immunoprecipitate (crude) from human brain.

Packing Type :

Dry Ice

Physical State :

Liquid

Purity and Specificity :

Anti-Synaptobrevin (VAMP) Antibody is directed against human synaptobrevin. Anti-Synaptobrevin was IgM purified by chromatography from cell culture supernatant. Reactivity is expected against bovine, mouse, pig, rat, rabbit and hamster.

Species Reactivity :

human, bovine, mouse, pig, rat, rabbit, hamster

Stabilizer :

0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Subclass :

IgM

Synonyms :

SYB1, Synaptobrevin, vesicle associated membrane protein, Vesicle-associated membrane protein 1, VAMP-1, Synaptobrevin-1, VAMP1, Vesicle-associated membrane protein 2, VAMP-2, Synaptobrevin-2, VAMP2, SYB2

Target Species :

Human

Background :

Synaptobrevin (also VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes, along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles. Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer’s disease.

Immunogen Type :

Native Protein

Low Endotoxin :

Sample Size :

Application Text :

Immunohistochemistry,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

P23763

NCBI :

AAH23286.1

Primary Image Name :

Western blot of Anti-Synaptobrevin (VAMP) (Mouse) Antibody - 200-301-E34

more info or order :

Rockland Immunochemicals product webpage