Calcitonin Gene Related Peptide (CGRP) Antibody | Rockland Immunochemicals 200-301-D15 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

Calcitonin Gene Related Peptide (CGRP) Antibody

catalog :

200-301-D15

quantity :

100 µL

price :

366.00 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4901

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation

more info or order :

Rockland Immunochemicals product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig 1d	Morelli C, Castaldi L, Brown S, Streich L, Websdale A, Taberner F, et al. Identification of a population of peripheral sensory neurons that regulates blood pressure. Cell Rep. 2021;35:109191 pubmed publisher
	Dhandapani R, Arokiaraj C, Taberner F, Pacifico P, Raja S, Nocchi L, et al. Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons. Nat Commun. 2018;9:1640 pubmed publisher

product information

Catalog Number :

200-301-D15

Name :

Anti-Calcitonin Gene Related Peptide (CGRP) (Mouse) Antibody - 200-301-D15

Display Name :

Calcitonin Gene Related Peptide (CGRP) Antibody

Application Note :

Anti-Calcitonin Gene Related Peptide antibody is suitable for use in ELISA and ICC. This product is not recommended for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Suggested positive controls are dorsal root ganglia, pancreas and gut.

Buffer :

0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Clonality :

Monoclonal

Clone ID :

4901

Concentration Value :

Titrated value sufficient to run approximately 10 mini blots.

Conjugation :

(None)

Size :

100 µL

Default Unit :

ELISA Dilution :

1:5,000

Immunohistochemistry Dilution :

1:50-1:100

IF Microscopy Dilution :

1:50-1:100

Immunoprecipitation Dilution :

1:50-1:100

Western Blot Dilution :

not recommended

Expiration :

Expiration date is one (1) year from date of opening.

Format :

IgG2a

Gene Name :

Calca

Host Animal :

Mouse

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-CGRP Monoclonal Antibody was produced by repeated immunizations with purified rat alpha-CGRP.

Packing Type :

Dry Ice

Physical State :

Liquid

Purity and Specificity :

Anti-CGRP Monoclonal Antibody is directed against rat CGRP protein. The antibody was purified from concentrated tissue culture supernate by Protein G chromatography. This antibody is specific for human and rat CGRP protein. A BLAST analysis was used to suggest cross-reactivity with CGRP from most mammalian sources based on very high homology with the immunizing sequence. Calcitonin Gene Related Peptide antibody also recognizes rat beta-CGRP and human alpha-CGRP (10-fold less sensitivity compared to rat alpha-CGRP).

Species Reactivity :

rat, human

Stabilizer :

0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol

Storage :

Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Subclass :

IgG2a

Synonyms :

Alpha-type CGRP, Calcitonin gene-related peptide I, Calcitonin gene-related peptide 1, CGRP-I, Calca, Calc

Target Species :

Rat

Background :

CGRP antibody recognizes Calcitonin Gene Related Peptide or CGRP which is a 37 amino acid peptide and is the most potent endogenous vasodilator currently known. CGRP is primarily produced in nervous tissue, however, its receptors are expressed throughout the body. CGRP is also strongly implicated in the vasodilatory effect of endogenous cannabinoid anandamide in the brain. This effect was found to be antagonized by capsazepine. CGRP is also currently a major target of research in regards to factors effecting the onset of migraine headaches. CGRP antibodies have been used successfully in immunoneutralization. Anti-CGRP antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Immunogen Type :

Recombinant Protein

Low Endotoxin :

Sample Size :

Application Text :

ELISA,Immunohistochemistry,IF Microscopy,Immunoprecipitation,Western Blot,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

2020 Price :

366.00 USD

UniProt :

P01256

NCBI :

NP_001029128.1

Primary Image Name :

Immunocytochemistry of Anti-Calcitonin Gene Related Peptide (CGRP) (Mouse) Antibody - 200-301-D15

more info or order :

Rockland Immunochemicals product webpage