IKB alpha Antibody | Rockland Immunochemicals 100-4167C product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

IKB alpha Antibody

catalog :

100-4167C

quantity :

100 µL

price :

359.00 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry

product information

Catalog Number :

100-4167C

Name :

Anti-IKBα C-terminal (RABBIT) Antibody - 100-4167C

Display Name :

IKB alpha Antibody

Application Note :

Anti-IkBa Antibody is suitable for western blotting, ELISA, and IHC. Researchers should determine optimal titers for applications that are not stated below.

Buffer :

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Clonality :

Polyclonal

Concentration Value :

80 mg/mL

Concentration Definition :

by Refractometry

Conjugation :

(None)

Size :

100 µL

Default Unit :

ELISA Dilution :

1:20,000 - 1:100,000

Immunohistochemistry Dilution :

1:1,000 - 1:5,000

Western Blot Dilution :

1:2,000 - 1:10,000

Expiration :

Expiration date is one (1) year from date of opening.

Format :

Antiserum

Gene Name :

IKBα

Host Animal :

Rabbit

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

IKB alpha Antibody was produced by repeated immunizations with a synthetic IkBa peptide corresponding to a region near the C-terminus of the human protein.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.1% (w/v) Sodium Azide

Purity and Specificity :

IKB alpha Antibody was prepared from monospecific antiserum by delipidation and defibrination. Anti- IkBa may react non-specifically with other proteins. Control peptide (code #100-4167P) will compete only with the specific reaction of antiserum with IkBa.

Species Reactivity :

human, mouse, rat

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Synonyms :

rabbit anti-IKB alpha Antibody, IkappaBalpha antibody, IKBA antibody, IKBalpha antibody, MAD3 antibody, NF kappa B inhibitor alpha antibody, NFKBI antibody, NFKBIA antibody

Target Species :

Human

Background :

Anti-IKB alpha Antibody detects IkBa. I-kappa-B-alpha inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, IKBA becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. Anti-IKBa Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction and Immunology research.

General Reference :

Hoffmann, A. et al. (2002) The IkB-NFkB Signaling Module: Temporal Control and Selective Gene Activation. Science 298:8; pp 1241-1245.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Target Domain of Reactivity :

C-Terminus

Application Text :

ELISA,Immunohistochemistry,Western Blot,

Other :

User Optimized

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

2019 Price :

359.00 USD

UniProt :

P25963

NCBI :

CAB65556.2

Primary Image Name :

Rabbit anti-IKBa C term WB