KDM1B Antibody | Rockland Immunochemicals 100-401-W43 product information

product summary

company name :

Rockland Immunochemicals

product type :

antibody

product name :

KDM1B Antibody

catalog :

100-401-W43

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

ELISA

more info or order :

Rockland Immunochemicals product webpage

product information

Catalog Number :

100-401-W43

Name :

Anti-KDM1B (RABBIT) Antibody - 100-401-W43

Display Name :

KDM1B Antibody

Application Note :

Anti-KDM1B Antibody is suitable for ELISA. Specific conditions for reactivity should be optimized by the end user.

Clonality :

Polyclonal

Concentration Value :

neat

Conjugation :

(None)

Size :

100 µL

Default Unit :

ELISA Dilution :

1:500

Expiration :

Expiration date is one (1) year from date of opening.

Format :

Antiserum

Gene Name :

KDM1B

Host Animal :

Rabbit

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen :

Anti-KDM1B Antibody was produced in rabbits by repeated immunizations with two different synthetic peptides containing a sequence from the N-terminus and internal region of the human KDM1B protein.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Preservative :

0.05% (w/v) Sodium Azide

Purity and Specificity :

Anti-KDM1B Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with KDM1B from other species not tested.

Species Reactivity :

Human

Storage :

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Subclass :

IgG

Synonyms :

Lysine-specific histone demethylase 1B, Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2, AOF1, C6orf193, LSD2

Target Species :

Human

Background :

KDM1B is a histone demethylase that demethylates lysine 4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. KDM1B is able to demethylate both mono- and di-methylated lysine 4 of histone H3, but has no effect on tri-methylated lysine 4, mono-, di- or tri-methylated lysine 9, mono-, di- or tri-methylated lysine 27, mono-, di- or tri-methylated lysine 36 of histone H3, or on mono-, di- or tri-methylated lysine 20 of histone H4. KDM1B is also required for de novo DNA methylation of a subset of imprinted genes during oogenesis. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Anti-KDM1B is ideal for research in Epigenetics and Gene Expression.

Immunogen Type :

Peptide

Low Endotoxin :

Sample Size :

Application Text :

ELISA,

Category :

Primary Antibodies

Conjugation Name :

Unconjugated

UniProt :

Q8NB78

NCBI :

NP_694587.3

Primary Image Name :

ELISA of anti-KDM1B antibody

more info or order :

Rockland Immunochemicals product webpage