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company name :
Rockland Immunochemicals
product type :
antibody
product name :
Anthrax Protective Antigen Antibody
catalog :
100-401-H55
quantity :
200 µL
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
anthrax bacterium
application :
western blot
more info or order :
Rockland Immunochemicals product webpage
product information
Catalog Number :
100-401-H55
Name :
Anti-Anthrax Protective Antigen (RABBIT) Antibody - 100-401-H55
Display Name :
Anthrax Protective Antigen Antibody
Application Note :
Anti-Anthrax PA (Protective Antigen) Antibody is suitable for use in WB. Expect a band approximately 83kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Buffer :
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Clonality :
Polyclonal
Conjugation :
(None)
Size :
200 µL
Default Unit :
ul
Western Blot Dilution :
1:100-1:1000
Expiration :
Expiration date is one (1) year from date of opening.
Format :
Antiserum
Gene Name :
pagA
Host Animal :
Rabbit
General Disclaimer Note :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
Immunogen :
Anthrax Protective Antigen Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to the internal region of the Anthrax PA protein.
Packing Type :
Dry Ice
Physical State :
Liquid
Preservative :
0.05% (w/v) Sodium Azide
Purity and Specificity :
Anti-Anthrax Protective Antigen Antibody is sera. A BLAST analysis was used to suggest cross-reactivity with Anti-Anthrax PA from multiple species based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Anthrax PA from other sources has not been determined.
Species Reactivity :
Bacillus anthracis
Stabilizer :
0.05% BSA
Storage :
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Subclass :
IgG
Synonyms :
pag, Anthrax Protective Antigen, Anthrax toxins translocating protein, PA-83, Protective antigen PA-20, PA20, Protective antigen PA-63, PA63
Target Species :
Bacillus
Background :
Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxic entry into cells. Anthrax PA is secreted from Bacillus anthracis as an 83 kD (PA83) protein which is cleaved by furin protease, releasing a 20 kD fragment. The 63 kD portion (PA63) of the cleavage product forms a heptamer, which binds the toxins LF and EF. This complex enters via receptor-mediated endocytosis where LF and EF exert their toxic effects. Anthrax PA is ideal for researchers interested in Neurobiology research.
Immunogen Type :
Peptide
Low Endotoxin :
No
Sample Size :
No
Target Domain of Reactivity :
Internal
Application Text :
Western Blot,
Category :
Primary Antibodies
Conjugation Name :
Unconjugated
UniProt :
P13423
NCBI :
NP_052806.1
Primary Image Name :
Anthrax Protective Antigen Western Blot
more info or order :
Rockland Immunochemicals product webpage
company information
Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
tech@rockland.com
https://www.rockland.com/
484-791-3823
headquarters: USA
Rockland Immunochemicals, Inc. produces Phosho-Site Specific Antibodies and Antibody based tools for basic, applied and clinical research. Our laboratory is located west of Philadelphia, Pennsylvania, USA. The technology base of the organization is the experience of its staff scientists in the production and purification of a wide range of antibodies through monoclonal & polyclonal antibody techniques utilizing in vitro and in vivo methods. Rockland's antibodies are suited for individuals performing Western Blotting, ELISA, Immunohistochemistry, Fluorescent Microscopy, High Content Screening and diagnostic kit production. Primary antibodies include Akt Pathway, Apolipoproteins, Apoptosis/Cell Cycle, Cytokines, Cell Signaling, Enzymes, Extracellular Matrix, Transcription Factors (NFkB) and Ubiquitin.