p63 protein-GST fusion | Rockland Immunochemicals 009-001-S68 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Rockland Immunochemicals

product type :

protein

product name :

p63 protein-GST fusion

catalog :

009-001-S68

quantity :

50 µg

price :

545.00 USD

product information

Catalog Number :

009-001-S68

Name :

p63 recombinant protein-GST fusion protein - 009-001-S68

Display Name :

p63 protein-GST fusion

Application Note :

p63 Protein is stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. p63 Protein is suitable for use in Western Blot and Kinase Assay. Expect a band approximately ~92kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Buffer :

See application note.

Concentration Value :

0.2 µg/µL

Conjugation :

(None)

Size :

50 µg

Default Unit :

µg

Western Blot Dilution :

User Optimized

Expiration :

Expiration date is one (1) year from date of opening.

Gene Name :

TP63

General Disclaimer Note :

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Packing Type :

Dry Ice

Physical State :

Liquid (sterile filtered)

Purity and Specificity :

Full-length recombinant human p63 was expressed by baculovirus in Sf9 cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >90% by densitometry.

Species Reactivity :

Human

Storage :

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Synonyms :

TP63, AIS, B, p51A, B, p51B, EEC3, KET, LMS, NBP, OFC8, p40, p51, p53CP, p73H, p73L, RHS, SHFM4, TP53CP, TP53L, TP73L, Tumor protein 63, p63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, Transformation-related protein 63, TP63, Tumor protein p73-like, p73L, p40, p51

Background :

p63 is the primordial member of the p53 family that acts in a conserved process of monitoring the integrity of the female germline, whereas the functions of p53 are restricted to vertebrate somatic cells for tumor suppression. p63 protein plays an important role in the development and maintenance of stratified epithelial tissues (1). p63 is critical for maintaining the progenitor-cell populations that are necessary to sustain epithelial development and morphogenesis (2). Mutations in p63 are associated with ectodermal dysplasia, cleft lip/palate syndrome 3 (EEC3) and split-hand/foot malformation 4 (SHFM4). p63 Protein is ideal for investigators involved in Signaling Proteins, Cell Cycle Proteins, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, Cellular Stress, Inflammation, JNK/SAPK Pathway, Metabolic Disorder, Neurobiology, and p38 Pathway research.

General Reference :

1. Yang, A., Schweitzer, R. et.al: p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 398: 714-718, 1999. 2. Suh, E.-K. et.al: p63 protects the female germ line during meiotic arrest. Nature 444: 624-628, 2006.

Low Endotoxin :

PSC Format :

Recombinant Protein

PSC Type :

Protein

Sample Size :

Application Text :

Western Blot,

Other :

Kinase Assay-User Optimized

Category :

Proteins and Peptides

Conjugation Name :

Unconjugated

2019 Price :

545.00 USD

NCBI :

NM_001114980