product summary
company name :
Reliatech GmbH
product type :
antibody
product name :
Prox-1
catalog :
102-PA32AG
quantity :
50
price :
210 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
Rabbit IG
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 59
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1a
Kim J, Park D, Bae H, Park D, Kim D, Lee C, et al. Impaired angiopoietin/Tie2 signaling compromises Schlemm's canal integrity and induces glaucoma. J Clin Invest. 2017;127:3877-3896 pubmed publisher
Quagliata L, Klusmeier S, Cremers N, Pytowski B, Harvey A, Pettis R, et al. Inhibition of VEGFR-3 activation in tumor-draining lymph nodes suppresses the outgrowth of lymph node metastases in the MT-450 syngeneic rat breast cancer model. Clin Exp Metastasis. 2014;31:351-65 pubmed publisher
Sleeckx N, Van Brantegem L, Van den Eynden G, Fransen E, Casteleyn C, Van Cruchten S, et al. Lymphangiogenesis in canine mammary tumours: a morphometric and prognostic study. J Comp Pathol. 2014;150:184-93 pubmed publisher
Rubin A, Kessaris N. PROX1: a lineage tracer for cortical interneurons originating in the lateral/caudal ganglionic eminence and preoptic area. PLoS ONE. 2013;8:e77339 pubmed publisher
Lachance P, Hazen A, Sevick Muraca E. Lymphatic vascular response to acute inflammation. PLoS ONE. 2013;8:e76078 pubmed publisher
Buttler K, Badar M, Seiffart V, Laggies S, Gross G, Wilting J, et al. De novo hem- and lymphangiogenesis by endothelial progenitor and mesenchymal stem cells in immunocompetent mice. Cell Mol Life Sci. 2014;71:1513-27 pubmed publisher
Buttler K, Becker J, Pukrop T, Wilting J. Maldevelopment of dermal lymphatics in Wnt5a-knockout-mice. Dev Biol. 2013;381:365-76 pubmed publisher
Benevenuto de Andrade B, Ramírez Amador V, Anaya Saavedra G, Martínez Mata G, Fonseca F, Graner E, et al. Expression of PROX-1 in oral Kaposi's sarcoma spindle cells. J Oral Pathol Med. 2014;43:132-6 pubmed publisher
Laco F, Grant M, Black R. Collagen-nanofiber hydrogel composites promote contact guidance of human lymphatic microvascular endothelial cells and directed capillary tube formation. J Biomed Mater Res A. 2013;101:1787-99 pubmed publisher
Sleeckx N, Van Brantegem L, Fransen E, Van den Eynden G, Casteleyn C, Veldhuis Kroeze E, et al. Evaluation of immunohistochemical markers of lymphatic and blood vessels in canine mammary tumours. J Comp Pathol. 2013;148:307-17 pubmed publisher
Aguilar B, Choi I, Choi D, Chung H, Lee S, Yoo J, et al. Lymphatic reprogramming by Kaposi sarcoma herpes virus promotes the oncogenic activity of the virus-encoded G-protein-coupled receptor. Cancer Res. 2012;72:5833-42 pubmed publisher
Lee A, Lee J, Jung Y, Kim D, Kang K, Lee S, et al. Vascular endothelial growth factor-C and -D are involved in lymphangiogenesis in mouse unilateral ureteral obstruction. Kidney Int. 2013;83:50-62 pubmed publisher
Becker J, Fröhlich J, Perske C, Pavlakovic H, Wilting J. Reelin signalling in neuroblastoma: migratory switch in metastatic stages. Int J Oncol. 2012;41:681-9 pubmed publisher
Keenan I, Rhee H, Chaudhry B, Henderson D. Origin of non-cardiac endothelial cells from an Isl1+ lineage. FEBS Lett. 2012;586:1790-4 pubmed publisher
Foskolou I, Stellas D, Rozani I, Lavigne M, Politis P. Prox1 suppresses the proliferation of neuroblastoma cells via a dual action in p27-Kip1 and Cdc25A. Oncogene. 2013;32:947-60 pubmed publisher
Nörder M, Gutierrez M, Zicari S, Cervi E, Caruso A, Guzman C. Lymph node-derived lymphatic endothelial cells express functional costimulatory molecules and impair dendritic cell-induced allogenic T-cell proliferation. FASEB J. 2012;26:2835-46 pubmed publisher
Hasenpusch Theil K, Magnani D, Amaniti E, Han L, Armstrong D, Theil T. Transcriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampus. Cereb Cortex. 2012;22:2878-93 pubmed publisher
Mentzel T, Schildhaus H, Palmedo G, Buttner R, Kutzner H. Postradiation cutaneous angiosarcoma after treatment of breast carcinoma is characterized by MYC amplification in contrast to atypical vascular lesions after radiotherapy and control cases: clinicopathological, immunohistochemical and molecular analy. Mod Pathol. 2012;25:75-85 pubmed publisher
Lee A, Kim D, Lee J, Jung Y, Kang K, Lee S, et al. Erythropoietin induces lymph node lymphangiogenesis and lymph node tumor metastasis. Cancer Res. 2011;71:4506-17 pubmed publisher
Akagami M, Kawada K, Kubo H, Kawada M, Takahashi M, Kaganoi J, et al. Transcriptional factor Prox1 plays an essential role in the antiproliferative action of interferon-? in esophageal cancer cells. Ann Surg Oncol. 2011;18:3868-77 pubmed publisher
Lobbardi R, Lambert G, Zhao J, Geisler R, Kim H, Rosa F. Fine-tuning of Hh signaling by the RNA-binding protein Quaking to control muscle development. Development. 2011;138:1783-94 pubmed publisher
Elkouris M, Balaskas N, Poulou M, Politis P, Panayiotou E, Malas S, et al. Sox1 maintains the undifferentiated state of cortical neural progenitor cells via the suppression of Prox1-mediated cell cycle exit and neurogenesis. Stem Cells. 2011;29:89-98 pubmed publisher
de Mooij Y, Van Den Akker N, Bekker M, Bartelings M, van Vugt J, Gittenberger de Groot A. Aberrant lymphatic development in euploid fetuses with increased nuchal translucency including Noonan syndrome. Prenat Diagn. 2011;31:159-66 pubmed publisher
Kholova I, Dragneva G, Cermáková P, Laidinen S, Kaskenpää N, Hazes T, et al. Lymphatic vasculature is increased in heart valves, ischaemic and inflamed hearts and in cholesterol-rich and calcified atherosclerotic lesions. Eur J Clin Invest. 2011;41:487-97 pubmed publisher
Dolez M, Nicolas J, Hirsinger E. Laminins, via heparan sulfate proteoglycans, participate in zebrafish myotome morphogenesis by modulating the pattern of Bmp responsiveness. Development. 2011;138:97-106 pubmed publisher
Sotiropoulou N, Bravou V, Kounelis S, Damaskou V, Papaspirou E, Papadaki H. Tumour expression of lymphangiogenic growth factors but not lymphatic vessel density is implicated in human cervical cancer progression. Pathology. 2010;42:629-36 pubmed publisher
Kim M, Koh Y, Kim K, Koh B, Nam D, Alitalo K, et al. CXCR4 signaling regulates metastasis of chemoresistant melanoma cells by a lymphatic metastatic niche. Cancer Res. 2010;70:10411-21 pubmed publisher
Choi I, Chung H, Ramu S, Lee H, Kim K, Lee S, et al. Visualization of lymphatic vessels by Prox1-promoter directed GFP reporter in a bacterial artificial chromosome-based transgenic mouse. Blood. 2011;117:362-5 pubmed publisher
Martin A, Gasse H, Staszyk C. Absence of lymphatic vessels in the dog dental pulp: an immunohistochemical study. J Anat. 2010;217:609-15 pubmed publisher
Gonzalez Nunez V, Nocco V, Budd A. Characterization of drCol 15a1b: a novel component of the stem cell niche in the zebrafish retina. Stem Cells. 2010;28:1399-411 pubmed publisher
Pedrioli D, Karpanen T, Dabouras V, Jurisic G, van de Hoek G, Shin J, et al. miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo. Mol Cell Biol. 2010;30:3620-34 pubmed publisher
von Kaisenberg C, Wilting J, Dork T, Nicolaides K, Meinhold Heerlein I, Hillemanns P, et al. Lymphatic capillary hypoplasia in the skin of fetuses with increased nuchal translucency and Turner's syndrome: comparison with trisomies and controls. Mol Hum Reprod. 2010;16:778-89 pubmed publisher
Becker J, Wang B, Pavlakovic H, Buttler K, Wilting J. Homeobox transcription factor Prox1 in sympathetic ganglia of vertebrate embryos: correlation with human stage 4s neuroblastoma. Pediatr Res. 2010;68:112-7 pubmed publisher
Wang Y, Nakayama M, Pitulescu M, Schmidt T, Bochenek M, Sakakibara A, et al. Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. Nature. 2010;465:483-6 pubmed publisher
Ji R, Eshita Y, Xing L, Miura M. Multiple expressions of lymphatic markers and morphological evolution of newly formed lymphatics in lymphangioma and lymph node lymphangiogenesis. Microvasc Res. 2010;80:195-201 pubmed publisher
Kang J, Yoo J, Lee S, Tang W, Aguilar B, Ramu S, et al. An exquisite cross-control mechanism among endothelial cell fate regulators directs the plasticity and heterogeneity of lymphatic endothelial cells. Blood. 2010;116:140-50 pubmed publisher
Akhmetshina A, Beer J, Zwerina K, Englbrecht M, Palumbo K, Dees C, et al. Decreased lymphatic vessel counts in patients with systemic sclerosis: association with fingertip ulcers. Arthritis Rheum. 2010;62:1513-22 pubmed publisher
Junginger J, Rötting A, Staszyk C, Kramer K, Hewicker Trautwein M. Identification of equine cutaneous lymphangioma by application of a lymphatic endothelial cell marker. J Comp Pathol. 2010;143:57-60 pubmed publisher
Hirakawa S, Detmar M, Kerjaschki D, Nagamatsu S, Matsuo K, Tanemura A, et al. Nodal lymphangiogenesis and metastasis: Role of tumor-induced lymphatic vessel activation in extramammary Paget's disease. Am J Pathol. 2009;175:2235-48 pubmed publisher
Kim K, Koh Y, Jeon B, Jang C, Han J, Kataru R, et al. Role of CD11b+ macrophages in intraperitoneal lipopolysaccharide-induced aberrant lymphangiogenesis and lymphatic function in the diaphragm. Am J Pathol. 2009;175:1733-45 pubmed publisher
de Mooij Y, Van Den Akker N, Bekker M, Bartelings M, Wisse L, van Vugt J, et al. Abnormal Shh and FOXC2 expression correlates with aberrant lymphatic development in human fetuses with increased nuchal translucency. Prenat Diagn. 2009;29:840-6 pubmed publisher
Requena L, El Shabrawi Caelen L, Walsh S, Segura S, Ziemer M, Hurt M, et al. Intralymphatic histiocytosis. A clinicopathologic study of 16 cases. Am J Dermatopathol. 2009;31:140-51 pubmed publisher
Nisato R, Buser R, Pepper M. Lymphatic endothelial cells: establishment of primaries and characterization of established lines. Methods Mol Biol. 2009;467:113-26 pubmed
Spinella F, Garrafa E, Di Castro V, Rosanò L, Nicotra M, Caruso A, et al. Endothelin-1 stimulates lymphatic endothelial cells and lymphatic vessels to grow and invade. Cancer Res. 2009;69:2669-76 pubmed publisher
Hadamitzky C, Blum K, Pabst R. Regeneration of autotransplanted avascular lymph nodes in the rat is improved by platelet-rich plasma. J Vasc Res. 2009;46:389-96 pubmed publisher
Kawai Y, Kaidoh M, Yokoyama Y, Sano K, Ohhashi T. Chemokine CCL2 facilitates ICAM-1-mediated interactions of cancer cells and lymphatic endothelial cells in sentinel lymph nodes. Cancer Sci. 2009;100:419-28 pubmed publisher
Jang C, Koh Y, Lim N, Kang H, Kim D, Park S, et al. Angiopoietin-2 exocytosis is stimulated by sphingosine-1-phosphate in human blood and lymphatic endothelial cells. Arterioscler Thromb Vasc Biol. 2009;29:401-7 pubmed publisher
Risebro C, Searles R, Melville A, Ehler E, Jina N, Shah S, et al. Prox1 maintains muscle structure and growth in the developing heart. Development. 2009;136:495-505 pubmed publisher
Vondenhoff M, van de Pavert S, Dillard M, Greuter M, Goverse G, Oliver G, et al. Lymph sacs are not required for the initiation of lymph node formation. Development. 2009;136:29-34 pubmed publisher
László V, Dezso K, Baghy K, Papp V, Kovalszky I, Safrany G, et al. Triiodothyronine accelerates differentiation of rat liver progenitor cells into hepatocytes. Histochem Cell Biol. 2008;130:1005-14 pubmed publisher
Yoon C, Hong B, Moon H, Lim S, Suh P, Kim Y, et al. Sphingosine-1-phosphate promotes lymphangiogenesis by stimulating S1P1/Gi/PLC/Ca2+ signaling pathways. Blood. 2008;112:1129-38 pubmed publisher
Buttler K, Ezaki T, Wilting J. Proliferating mesodermal cells in murine embryos exhibiting macrophage and lymphendothelial characteristics. BMC Dev Biol. 2008;8:43 pubmed publisher
Bekker M, Van Den Akker N, de Mooij Y, Bartelings M, van Vugt J, Gittenberger de Groot A. Jugular lymphatic maldevelopment in Turner syndrome and trisomy 21: different anomalies leading to nuchal edema. Reprod Sci. 2008;15:295-304 pubmed publisher
Nguyen V, Fürhapter C, Obexer P, Stössel H, Romani N, Sepp N. Endothelial cells from cord blood CD133+CD34+ progenitors share phenotypic, functional and gene expression profile similarities with lymphatics. J Cell Mol Med. 2009;13:522-34 pubmed publisher
Dudas J, Mansuroglu T, Moriconi F, Haller F, Wilting J, Lorf T, et al. Altered regulation of Prox1-gene-expression in liver tumors. BMC Cancer. 2008;8:92 pubmed publisher
Kawai Y, Hosaka K, Kaidoh M, Minami T, Kodama T, Ohhashi T. Heterogeneity in immunohistochemical, genomic, and biological properties of human lymphatic endothelial cells between initial and collecting lymph vessels. Lymphat Res Biol. 2008;6:15-27 pubmed publisher
Ushijima N, Inoue K, Domon T, Yoshida S. Distribution and organization of lymphatic vessels in the mouse gingiva: An immunohistochemical study with LYVE-1. Arch Oral Biol. 2008;53:652-8 pubmed publisher
Misra K, Mishra K, Gui H, Matise M. Prox1 regulates a transitory state for interneuron neurogenesis in the spinal cord. Dev Dyn. 2008;237:393-402 pubmed publisher
Rompani S, Cepko C. Retinal progenitor cells can produce restricted subsets of horizontal cells. Proc Natl Acad Sci U S A. 2008;105:192-7 pubmed
product information
Product Name :
Prox-1
Reactivity :
Anti-Human
Clonality :
Polyclonal Antibody
Host Species :
Rabbit
Cat.-Number :
102-PA32AG
SIZE [ug] :
50
Price [Euro] :
210 USD
Clone :
Rabbit IG
Application :
WB, IF
more info or order :
company information
Reliatech GmbH
Lindener Str. 15
38300 Wolfenbuettel
info@reliatech.de
www.reliatech.de
49 0 5331 8586 987
headquarters: Germany