RUNX2/CBFA1 Antibody | R&D Systems MAB2006 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

RUNX2/CBFA1 Antibody

catalog :

MAB2006

quantity :

100 ug (also 25 ug)

price :

411 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

232902

reactivity :

human

application :

immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 20

Reference
Song Q, Yang Y, Jiang D, Qin Z, Xu C, Wang H, et al. Proteomic analysis reveals key differences between squamous cell carcinomas and adenocarcinomas across multiple tissues. Nat Commun. 2022;13:4167 pubmed publisher
Xu C, Dinh V, Kruse K, Jeong H, Watson E, Adams S, et al. Induction of osteogenesis by bone-targeted Notch activation. elife. 2022;11: pubmed publisher
Minguzzi M, Panichi V, D Adamo S, Cetrullo S, Cattini L, Flamigni F, et al. Pleiotropic Roles of NOTCH1 Signaling in the Loss of Maturational Arrest of Human Osteoarthritic Chondrocytes. Int J Mol Sci. 2021;22: pubmed publisher
Yao J, Wu X, Qiao X, Zhang D, Zhang L, Ma J, et al. Shifting osteogenesis in vascular calcification. JCI Insight. 2021;6: pubmed publisher
Oe Y, Mitsui S, Sato E, Shibata N, Kisu K, Sekimoto A, et al. Lack of Endothelial Nitric Oxide Synthase Accelerates Ectopic Calcification in Uremic Mice Fed an Adenine and High Phosphorus Diet. Am J Pathol. 2021;191:283-293 pubmed publisher
Supakul S, Yao K, Ochi H, Shimada T, Hashimoto K, Sunamura S, et al. Pericytes as a Source of Osteogenic Cells in Bone Fracture Healing. Int J Mol Sci. 2019;20: pubmed publisher
Day A, Francis W, Fu K, Pieper I, Guy O, Xia Z. Osteogenic Potential of Human Umbilical Cord Mesenchymal Stem Cells on Coralline Hydroxyapatite/Calcium Carbonate Microparticles. Stem Cells Int. 2018;2018:4258613 pubmed publisher
Lisignoli G, Lambertini E, Manferdini C, Gabusi E, Penolazzi L, Paolella F, et al. Collagen type XV and the 'osteogenic status'. J Cell Mol Med. 2017;21:2236-2244 pubmed publisher
Langen U, Pitulescu M, Kim J, Enriquez Gasca R, Sivaraj K, Kusumbe A, et al. Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. Nat Cell Biol. 2017;19:189-201 pubmed publisher
Bradaschia Correa V, Josephson A, Mehta D, Mizrahi M, Neibart S, Liu C, et al. The Selective Serotonin Reuptake Inhibitor Fluoxetine Directly Inhibits Osteoblast Differentiation and Mineralization During Fracture Healing in Mice. J Bone Miner Res. 2017;32:821-833 pubmed publisher
Guemes M, Garcia A, Rigueur D, Runke S, Wang W, Zhao G, et al. GATA4 is essential for bone mineralization via ER? and TGF?/BMP pathways. J Bone Miner Res. 2014;29:2676-87 pubmed publisher
Ramasamy S, Kusumbe A, Wang L, Adams R. Endothelial Notch activity promotes angiogenesis and osteogenesis in bone. Nature. 2014;507:376-380 pubmed publisher
Kusumbe A, Ramasamy S, Adams R. Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone. Nature. 2014;507:323-328 pubmed publisher
Wang L, Benedito R, Bixel M, Zeuschner D, Stehling M, Savendahl L, et al. Identification of a clonally expanding haematopoietic compartment in bone marrow. EMBO J. 2013;32:219-30 pubmed publisher
Pai A, Leaf E, El Abbadi M, Giachelli C. Elastin degradation and vascular smooth muscle cell phenotype change precede cell loss and arterial medial calcification in a uremic mouse model of chronic kidney disease. Am J Pathol. 2011;178:764-73 pubmed publisher
Todoerti K, Lisignoli G, Storti P, Agnelli L, Novara F, Manferdini C, et al. Distinct transcriptional profiles characterize bone microenvironment mesenchymal cells rather than osteoblasts in relationship with multiple myeloma bone disease. Exp Hematol. 2010;38:141-53 pubmed publisher
El Abbadi M, Pai A, Leaf E, Yang H, Bartley B, Quan K, et al. Phosphate feeding induces arterial medial calcification in uremic mice: role of serum phosphorus, fibroblast growth factor-23, and osteopontin. Kidney Int. 2009;75:1297-1307 pubmed publisher
Ruiz S, Chen C. Emergence of patterned stem cell differentiation within multicellular structures. Stem Cells. 2008;26:2921-7 pubmed publisher
Krum S, Miranda Carboni G, Hauschka P, Carroll J, Lane T, Freedman L, et al. Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. EMBO J. 2008;27:535-45 pubmed publisher
Curran J, Chen R, Hunt J. The guidance of human mesenchymal stem cell differentiation in vitro by controlled modifications to the cell substrate. Biomaterials. 2006;27:4783-93 pubmed

image

image 1 :

RUNX2/CBFA1 antibody in U2OS Human Cell Line by Immunocytochemistry (ICC).

product information

brand :

R&D Systems

master code :

MAB2006

SKU :

MAB2006

product name :

RUNX2/CBFA1 Antibody

description :

The Human RUNX2/CBFA1 Antibody from R&D Systems is a rat monoclonal antibody to RUNX2/CBFA1. This antibody reacts with human. The Human RUNX2/CBFA1 Antibody has been validated for the following applications: Immunocytochemistry.

target :

RUNX2/CBFA1

category :

Primary Antibodies

sizes available :

100 ug (also 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

232902

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant human RUNX2/CBFA1 isoform 2, Lys233-Tyr418, Accession # Q13950

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human RUNX2/CBFA1

gene symbol :

RUNX2

accessionNumbers :

Q13950

applications :

Immunocytochemistry

USD :

411 USD

alt names :

Acute myeloid leukemia 3 protein, CBFA1, CBF-alpha-1, CCD1, CCDAML3, CLCD, Core-binding factor subunit alpha-1, core-binding factor, runt domain, alpha subunit 1, MGC120023, ML3, oncogene AML-3, OSF2, OSF-2, osteoblast-specific transcription factor 2, PEA2aA, PEA2-alpha A, PEBP2A, PEBP2aA, PEBP2-alpha A, polyomavirus enhancer-binding protein 2 alpha A subunit, runt domain, alpha subunit 1, runt related transcription factor 2, runt-related transcription factor 2, RUNX2, SL3/AKV core-binding factor alpha A subunit, SL3-3 enhancer factor 1 alpha A subunit

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage