Wan D, Ai S, Ouyang H, Cheng L. Activation of 4-1BB signaling in bone marrow stromal cells triggers bone loss via the p-38 MAPK-DKK1 axis in aged mice. Exp Mol Med. 2021;53:654-666 pubmed publisher

Wang L, Lin M, Liu K, Chiou S, Wang S, Chai C, et al. WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism. Autophagy. 2021;:1-16 pubmed publisher

Wang Y, Song M, Liu M, Zhang G, Zhang X, Li M, et al. Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity. Cell Rep. 2021;35:108948 pubmed publisher

Bednarczyk M, Medina Montano C, Fittler F, Stege H, Roskamp M, Kuske M, et al. Complement-Opsonized Nano-Carriers Are Bound by Dendritic Cells (DC) via Complement Receptor (CR)3, and by B Cell Subpopulations via CR-1/2, and Affect the Activation of DC and B-1 Cells. Int J Mol Sci. 2021;22: pubmed publisher

Joseph R, Soundararajan R, Vasaikar S, Yang F, Allton K, Tian L, et al. CD8+ T cells inhibit metastasis and CXCL4 regulates its function. Br J Cancer. 2021;125:176-189 pubmed publisher

Shi H, Sun L, Wang Y, Liu A, Zhan X, Li X, et al. N4BP1 negatively regulates NF-κB by binding and inhibiting NEMO oligomerization. Nat Commun. 2021;12:1379 pubmed publisher

Germic N, Fettrelet T, Stojkov D, Hosseini A, Horn M, Karaulov A, et al. The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells. 2021;10: pubmed publisher

Wang H, Teng X, Abboud G, Li W, Ye S, Morel L. D-mannose ameliorates autoimmune phenotypes in mouse models of lupus. BMC Immunol. 2021;22:1 pubmed publisher

Arya R, Goswami R, Rahaman S. Mechanotransduction via a TRPV4-Rac1 signaling axis plays a role in multinucleated giant cell formation. J Biol Chem. 2021;296:100129 pubmed publisher

Zhao N, Dong W, Kim H, Moallemian R, Lv J, Wang H, et al. Capping protein regulator and myosin 1 linker 3 regulates transcription of key cytokines in activated phagocytic cells. Cell Signal. 2021;78:109848 pubmed publisher

Park M, Baek J, Kim S, Jung K, Choi J, Park S, et al. Myeloid-derived suppressor cells therapy enhance immunoregulatory properties in acute graft versus host disease with combination of regulatory T cells. J Transl Med. 2020;18:483 pubmed publisher

Hyun Y, Seo S, Choi W, Kwon H, Kim D, Jeong S, et al. Endogenous DEL-1 restrains melanoma lung metastasis by limiting myeloid cell-associated lung inflammation. Sci Adv. 2020;6: pubmed publisher

Khaliullin T, Kisin E, Guppi S, Yanamala N, Zhernovkov V, Shvedova A. Differential responses of murine alveolar macrophages to elongate mineral particles of asbestiform and non-asbestiform varieties: Cytotoxicity, cytokine secretion and transcriptional changes. Toxicol Appl Pharmacol. 2020;409:115302 pubmed publisher

McCauley M, O Rourke J, Yáñez A, Markman J, Ho R, Wang X, et al. C9orf72 in myeloid cells suppresses STING-induced inflammation. Nature. 2020;585:96-101 pubmed publisher

Koide M, Yamashita T, Murakami K, Uehara S, Nakamura K, Nakamura M, et al. Sclerostin expression in trabecular bone is downregulated by osteoclasts. Sci Rep. 2020;10:13751 pubmed publisher

Maruyama K, Kidoya H, Takemura N, Sugisawa E, Takeuchi O, Kondo T, et al. Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages. Cell Rep. 2020;32:107906 pubmed publisher

Kubota M, Iizasa E, Chuuma Y, Kiyohara H, Hara H, Yoshida H. Adjuvant activity of Mycobacteria-derived mycolic acids. Heliyon. 2020;6:e04064 pubmed publisher

Lee K, Zhang Z, Achuthan A, Fleetwood A, Smith J, Hamilton J, et al. IL-23 in arthritic and inflammatory pain development in mice. Arthritis Res Ther. 2020;22:123 pubmed publisher

Thak E, Lee S, Xu Vanpala S, Lee D, Chung S, Bahn Y, et al. Core N-Glycan Structures Are Critical for the Pathogenicity of Cryptococcus neoformans by Modulating Host Cell Death. MBio. 2020;11: pubmed publisher

Guo X, Pan Y, Xiong M, Sanapala S, Anastasaki C, Cobb O, et al. Midkine activation of CD8+ T cells establishes a neuron-immune-cancer axis responsible for low-grade glioma growth. Nat Commun. 2020;11:2177 pubmed publisher

Lin W, Xu Y, Chen X, Liu J, Weng Y, Zhuang Q, et al. Radiation-induced small extracellular vesicles as "carriages" promote tumor antigen release and trigger antitumor immunity. Theranostics. 2020;10:4871-4884 pubmed publisher

Fan H, Li D, Guan X, Yang Y, Yan J, Shi J, et al. MsrA Suppresses Inflammatory Activation of Microglia and Oxidative Stress to Prevent Demyelination via Inhibition of the NOX2-MAPKs/NF-κB Signaling Pathway. Drug Des Devel Ther. 2020;14:1377-1389 pubmed publisher

Rossi A, Lucarini V, Macchia I, Sestili P, Buccione C, Donati S, et al. Tumor-Intrinsic or Drug-Induced Immunogenicity Dictates the Therapeutic Success of the PD1/PDL Axis Blockade. Cells. 2020;9: pubmed publisher

Goda C, Balli D, Black M, Milewski D, Le T, Ustiyan V, et al. Loss of FOXM1 in macrophages promotes pulmonary fibrosis by activating p38 MAPK signaling pathway. PLoS Genet. 2020;16:e1008692 pubmed publisher

Zhao Y, Wang J, Min Z, Peng L, Qi S, Lin W. I-alowCD11bhigh DC Regulates the Immune Response in the Eyes of Experimental Autoimmune Uveitis. Mediators Inflamm. 2020;2020:6947482 pubmed publisher

von Roemeling C, Wang Y, Qie Y, Yuan H, Zhao H, Liu X, et al. Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity. Nat Commun. 2020;11:1508 pubmed publisher

Viaud M, Abdel Wahab O, Gall J, Ivanov S, Guinamard R, Sore S, et al. ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms. Cell Rep. 2020;30:3397-3410.e5 pubmed publisher

Elesela S, Morris S, Narayanan S, Kumar S, Lombard D, Lukacs N. Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells. PLoS Pathog. 2020;16:e1008319 pubmed publisher

Somanathan S, Calcedo R, Wilson J. Adenovirus-Antibody Complexes Contributed to Lethal Systemic Inflammation in a Gene Therapy Trial. Mol Ther. 2020;28:784-793 pubmed publisher

de Rezende M, Ng Blichfeldt J, Justo G, Paredes Gamero E, Gosens R. Divergent effects of Wnt5b on IL-3- and GM-CSF-induced myeloid differentiation. Cell Signal. 2020;67:109507 pubmed publisher

Chen M, Huang M, Yu W, Lee S, Wang J, Cheng T, et al. Antibody blockade of Dectin-2 suppresses house dust mite-induced Th2 cytokine production in dendritic cell- and monocyte-depleted peripheral blood mononuclear cell co-cultures from asthma patients. J Biomed Sci. 2019;26:97 pubmed publisher

Wu L, Luo Z, Liu Y, Jia L, Jiang Y, Du J, et al. Aspirin inhibits RANKL-induced osteoclast differentiation in dendritic cells by suppressing NF-κB and NFATc1 activation. Stem Cell Res Ther. 2019;10:375 pubmed publisher

Birmpilis A, Karachaliou C, Samara P, Ioannou K, Selemenakis P, Kostopoulos I, et al. Antitumor Reactive T-Cell Responses Are Enhanced In Vivo by DAMP Prothymosin Alpha and Its C-Terminal Decapeptide. Cancers (Basel). 2019;11: pubmed publisher

Nagai J, Balestrieri B, Fanning L, Kyin T, Cirka H, Lin J, et al. P2Y6 signaling in alveolar macrophages prevents leukotriene-dependent type 2 allergic lung inflammation. J Clin Invest. 2019;129:5169-5186 pubmed publisher

Hsieh C, Hung C, Chiang M, Tsai Y, He J. Hepatic Stellate Cells Enhance Liver Cancer Progression by Inducing Myeloid-Derived Suppressor Cells through Interleukin-6 Signaling. Int J Mol Sci. 2019;20: pubmed publisher

Garo L, Ajay A, Fujiwara M, Beynon V, Kuhn C, Gabriely G, et al. Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity. Cell Rep. 2019;28:3353-3366.e5 pubmed publisher

Araujo L, Maricato J, Guereschi M, Takenaka M, Nascimento V, de Melo F, et al. The Sympathetic Nervous System Mitigates CNS Autoimmunity via β2-Adrenergic Receptor Signaling in Immune Cells. Cell Rep. 2019;28:3120-3130.e5 pubmed publisher

Ondee T, Gillen J, Visitchanakun P, Somparn P, Issara Amphorn J, Dang Phi C, et al. Lipocalin-2 (Lcn-2) Attenuates Polymicrobial Sepsis with LPS Preconditioning (LPS Tolerance) in FcGRIIb Deficient Lupus Mice. Cells. 2019;8: pubmed publisher

Cho K, Kang S, Kim S, Mun S, Yu H, Roh H. Dendritic cells and M2 macrophage play an important role in suppression of Th2-mediated inflammation by adipose stem cells-derived extracellular vesicles. Stem Cell Res. 2019;39:101500 pubmed publisher

Martinov T, Swanson L, Breed E, Tucker C, Dwyer A, Johnson J, et al. Programmed Death-1 Restrains the Germinal Center in Type 1 Diabetes. J Immunol. 2019;203:844-852 pubmed publisher

Prill H, Luu A, Yip B, Holtzinger J, Lo M, Christianson T, et al. Differential Uptake of NAGLU-IGF2 and Unmodified NAGLU in Cellular Models of Sanfilippo Syndrome Type B. Mol Ther Methods Clin Dev. 2019;14:56-63 pubmed publisher

Sharif S, Ueda N, Nakatani Y, Wise L, Clifton S, Lateef Z, et al. Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand Specificity. Front Microbiol. 2019;10:1421 pubmed publisher

Zhao R, Shao X, Jia G, Huang Y, Liu Z, Song B, et al. Anti-cervical carcinoma effect of Portulaca oleracea L. polysaccharides by oral administration on intestinal dendritic cells. BMC Complement Altern Med. 2019;19:161 pubmed publisher

Kurilin V, Khantakova J, Tereschenko V, Lopatnikova J, Obleukhova I, Sennikov S. The Effects of Immunosuppressive Factors on Primary Dendritic Cells from C57BL/6 and CBA Mice. J Immunol Res. 2019;2019:7029726 pubmed publisher

Capitano M, Mor Vaknin N, Saha A, Cooper S, Legendre M, Guo H, et al. Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling. J Clin Invest. 2019;129:2555-2570 pubmed publisher

Bossowska Nowicka M, Mielcarska M, Romaniewicz M, Kaczmarek M, Gregorczyk Zboroch K, Struzik J, et al. Ectromelia virus suppresses expression of cathepsins and cystatins in conventional dendritic cells to efficiently execute the replication process. BMC Microbiol. 2019;19:92 pubmed publisher

Li C, Dong L, Su R, Bi Y, Qing Y, Deng X, et al. Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC. Haematologica. 2019;: pubmed publisher

Mair B, Tomic J, Masud S, Tonge P, Weiss A, Usaj M, et al. Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies. Cell Rep. 2019;27:599-615.e12 pubmed publisher

Matsumura T, Ikebe T, Arikawa K, Hosokawa M, Aiko M, Iguchi A, et al. Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice. Cell Rep. 2019;27:561-571.e6 pubmed publisher

Wang J, Sun J, Liu L, Flies D, Nie X, Toki M, et al. Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy. Nat Med. 2019;25:656-666 pubmed publisher

Ahn M, Anderson D, Zhang Q, Tan C, Lim B, Luko K, et al. Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host. Nat Microbiol. 2019;4:789-799 pubmed publisher

Kramer K, Al Barwani F, Baird M, Young V, Larsen D, Ward V, et al. Functionalisation of Virus-Like Particles Enhances Antitumour Immune Responses. J Immunol Res. 2019;2019:5364632 pubmed publisher

Yasuda K, Kitagawa Y, Kawakami R, Isaka Y, Watanabe H, Kondoh G, et al. Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation. Nat Commun. 2019;10:549 pubmed publisher

Ribezzo F, Snoeren I, Ziegler S, Stoelben J, Olofsen P, Henic A, et al. Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome. Leukemia. 2019;: pubmed publisher

Zebertavage L, Bambina S, Shugart J, Alice A, Zens K, Lauer P, et al. A microbial-based cancer vaccine for induction of EGFRvIII-specific CD8+ T cells and anti-tumor immunity. PLoS ONE. 2019;14:e0209153 pubmed publisher

Tasian S, Casas J, Posocco D, Gandre Babbe S, Gagne A, Liang G, et al. Mutation-specific signaling profiles and kinase inhibitor sensitivities of juvenile myelomonocytic leukemia revealed by induced pluripotent stem cells. Leukemia. 2019;33:181-190 pubmed publisher

Tong Q, Zhu Y, Zhang D, Cai Q, Qu W, Cooper C, et al. MicroRNA Quantitation During Dendritic Cell Endocytosis Using Imaging Flow Cytometry: Key Factors and Requirements. Cell Physiol Biochem. 2018;51:793-811 pubmed publisher

Sturrock A, Woller D, Freeman A, Sanders K, Paine R. Consequences of Hypoxia for the Pulmonary Alveolar Epithelial Cell Innate Immune Response. J Immunol. 2018;201:3411-3420 pubmed publisher

Zhang C, Jiang M, Zhou H, Liu W, Wang C, Kang Z, et al. TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation. J Clin Invest. 2018;128:5399-5412 pubmed publisher

Rubio Araiz A, Finucane O, Keogh S, Lynch M. Anti-TLR2 antibody triggers oxidative phosphorylation in microglia and increases phagocytosis of β-amyloid. J Neuroinflammation. 2018;15:247 pubmed publisher

Wang Y, Su L, Morin M, Jones B, Mifune Y, Shi H, et al. Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice. Proc Natl Acad Sci U S A. 2018;115:E8698-E8706 pubmed publisher

Piao W, Xiong Y, Famulski K, Brinkman C, Li L, Toney N, et al. Regulation of T cell afferent lymphatic migration by targeting LTβR-mediated non-classical NFκB signaling. Nat Commun. 2018;9:3020 pubmed publisher

Srivastava S, Katorcha E, Makarava N, Barrett J, Loane D, Baskakov I. Inflammatory response of microglia to prions is controlled by sialylation of PrPSc. Sci Rep. 2018;8:11326 pubmed publisher

Hsieh C, Lin C, He J, Chiang M, Wang Y, Tsai Y, et al. Administration of cytokine-induced myeloid-derived suppressor cells ameliorates renal fibrosis in diabetic mice. Stem Cell Res Ther. 2018;9:183 pubmed publisher

Esher S, Ost K, Kohlbrenner M, Pianalto K, Telzrow C, Campuzano A, et al. Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition. PLoS Pathog. 2018;14:e1007126 pubmed publisher

Rasheed A, Tsai R, Cummins C. Loss of the Liver X Receptors Disrupts the Balance of Hematopoietic Populations, With Detrimental Effects on Endothelial Progenitor Cells. J Am Heart Assoc. 2018;7: pubmed publisher

Kinsella S, Fichtner M, Watters O, König H, Prehn J. Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation. J Neuroinflammation. 2018;15:130 pubmed publisher

Nagase R, Inoue D, Pastore A, Fujino T, Hou H, Yamasaki N, et al. Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation. J Exp Med. 2018;215:1729-1747 pubmed publisher

Chu L, Indramohan M, Ratsimandresy R, Gangopadhyay A, Morris E, Monack D, et al. The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages. Nat Commun. 2018;9:996 pubmed publisher

Zhao Y, Wu X, Li X, Jiang L, Gui X, Liu Y, et al. TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function. Neuron. 2018;97:1023-1031.e7 pubmed publisher

Sun B, Zhu L, Tao Y, Sun H, Li Y, Wang P, et al. Characterization and allergic role of IL-33-induced neutrophil polarization. Cell Mol Immunol. 2018;15:782-793 pubmed publisher

Wang H, Bei L, Shah C, Huang W, Platanias L, Eklund E. The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia. Oncogene. 2018;37:2532-2544 pubmed publisher

Szpak D, Izem L, Verbovetskiy D, Soloviev D, Yakubenko V, Pluskota E. αMβ2 Is Antiatherogenic in Female but Not Male Mice. J Immunol. 2018;200:2426-2438 pubmed publisher

Nixon A, Neely E, Simpson I, Connor J. The role of HFE genotype in macrophage phenotype. J Neuroinflammation. 2018;15:30 pubmed publisher

O Sullivan S, O Sullivan C, Healy L, Dev K, Sheridan G. Sphingosine 1-phosphate receptors regulate TLR4-induced CXCL5 release from astrocytes and microglia. J Neurochem. 2018;144:736-747 pubmed publisher

Kim Y, Kim M, Lee K, Hong J, Oh M, Kim S, et al. Activated leucocyte cell adhesion molecule (ALCAM/CD166) regulates T cell responses in a murine model of food allergy. Clin Exp Immunol. 2018;192:151-164 pubmed publisher

Borriello F, Pietrasanta C, Lai J, Walsh L, Sharma P, O Driscoll D, et al. Identification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization. Front Immunol. 2017;8:1772 pubmed publisher

Zhang M, Chun L, Sandoval V, Graor H, Myers J, Nthale J, et al. Systemic administration of β-glucan of 200 kDa modulates melanoma microenvironment and suppresses metastatic cancer. Oncoimmunology. 2018;7:e1387347 pubmed publisher

Ahn J, Son S, Oliveira S, Barber G. STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis. Cell Rep. 2017;21:3873-3884 pubmed publisher

Westendorp B, Büller N, Karpus O, van Dop W, Koster J, Versteeg R, et al. Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response. Cell Mol Gastroenterol Hepatol. 2018;5:67-82.e1 pubmed publisher

Laiño J, Wangorsch A, Blanco F, Wolfheimer S, Krause M, Flaczyk A, et al. Targeting of Immune Cells by Dual TLR2/7 Ligands Suppresses Features of Allergic Th2 Immune Responses in Mice. J Immunol Res. 2017;2017:7983217 pubmed publisher

Floudas A, Cluxton C, Fahel J, Khan A, Saunders S, Amu S, et al. Composition of the Schistosoma mansoni worm secretome: Identification of immune modulatory Cyclophilin A. PLoS Negl Trop Dis. 2017;11:e0006012 pubmed publisher

Song C, Phuengkham H, Kim S, Lee M, Jeong J, Shin S, et al. Aminated nanomicelles as a designer vaccine adjuvant to trigger inflammasomes and multiple arms of the innate immune response in lymph nodes. Int J Nanomedicine. 2017;12:7501-7517 pubmed publisher

Parviainen L, Dihanich S, Anderson G, Wong A, Brooks H, Abeti R, et al. Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons. Acta Neuropathol Commun. 2017;5:74 pubmed publisher

Shrestha C, Assani K, Rinehardt H, Albastroiu F, Zhang S, Shell R, et al. Cysteamine-mediated clearance of antibiotic-resistant pathogens in human cystic fibrosis macrophages. PLoS ONE. 2017;12:e0186169 pubmed publisher

Schülke S, Kuttich K, Wolfheimer S, Duschek N, Wangorsch A, Reuter A, et al. Conjugation of wildtype and hypoallergenic mugwort allergen Art v 1 to flagellin induces IL-10-DC and suppresses allergen-specific TH2-responses in vivo. Sci Rep. 2017;7:11782 pubmed publisher

Kim S, Mun B, Lee S, Joh Y, Lee H, Ji K, et al. TREM2 promotes Aβ phagocytosis by upregulating C/EBPα-dependent CD36 expression in microglia. Sci Rep. 2017;7:11118 pubmed publisher

Chiu D, Tse A, Xu I, Di Cui J, Lai R, Li L, et al. Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma. Nat Commun. 2017;8:517 pubmed publisher

Sorgi C, Zarini S, Martin S, Sanchez R, Scandiuzzi R, Gijón M, et al. Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid. Sci Rep. 2017;7:10981 pubmed publisher

Antonios J, Soto H, Everson R, Moughon D, Wang A, Orpilla J, et al. Detection of immune responses after immunotherapy in glioblastoma using PET and MRI. Proc Natl Acad Sci U S A. 2017;114:10220-10225 pubmed publisher

Thornton P, Sevalle J, Deery M, Fraser G, Zhou Y, Ståhl S, et al. TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant. EMBO Mol Med. 2017;9:1366-1378 pubmed publisher

Schneider K, Watson N, Minchenberg S, Massa P. The influence of macrophage growth factors on Theiler's Murine Encephalomyelitis Virus (TMEV) infection and activation of macrophages. Cytokine. 2018;102:83-93 pubmed publisher

Kim S, Jang Y, Hyung K, Lee D, Hyun K, Park S, et al. Therapeutic Effects of Methanol Extract from Euphorbia kansui Radix on Imiquimod-Induced Psoriasis. J Immunol Res. 2017;2017:7052560 pubmed publisher

Okamoto N, Mizote K, Honda H, Saeki A, Watanabe Y, Yamaguchi Miyamoto T, et al. Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex. J Biol Chem. 2017;292:15378-15394 pubmed publisher

McDonough A, Lee R, Noor S, Lee C, Le T, Iorga M, et al. Ischemia/Reperfusion Induces Interferon-Stimulated Gene Expression in Microglia. J Neurosci. 2017;37:8292-8308 pubmed publisher

Savage A, Liang H, Locksley R. The Development of Steady-State Activation Hubs between Adult LTi ILC3s and Primed Macrophages in Small Intestine. J Immunol. 2017;199:1912-1922 pubmed publisher

Uchiyama R, Yonehara S, Taniguchi S, Ishido S, Ishii K, Tsutsui H. Inflammasome and Fas-Mediated IL-1? Contributes to Th17/Th1 Cell Induction in Pathogenic Bacterial Infection In Vivo. J Immunol. 2017;199:1122-1130 pubmed publisher

Szulc Dąbrowska L, Struzik J, Ostrowska A, Guzera M, Toka F, Bossowska Nowicka M, et al. Functional paralysis of GM-CSF-derived bone marrow cells productively infected with ectromelia virus. PLoS ONE. 2017;12:e0179166 pubmed publisher

Zhu J, Yao K, Guo J, Shi H, Ma L, Wang Q, et al. miR-181a and miR-150 regulate dendritic cell immune inflammatory responses and cardiomyocyte apoptosis via targeting JAK1-STAT1/c-Fos pathway. J Cell Mol Med. 2017;21:2884-2895 pubmed publisher

Ao J, Zhu X, Chai Z, Cai H, Zhang Y, Zhang K, et al. Colony-Stimulating Factor 1 Receptor Blockade Inhibits Tumor Growth by Altering the Polarization of Tumor-Associated Macrophages in Hepatocellular Carcinoma. Mol Cancer Ther. 2017;16:1544-1554 pubmed publisher

Wang J, Ye H, Zhang D, Cheng K, Hu Y, Yu X, et al. Cancer-derived Circulating MicroRNAs Promote Tumor Angiogenesis by Entering Dendritic Cells to Degrade Highly Complementary MicroRNAs. Theranostics. 2017;7:1407-1421 pubmed publisher

Son C, Bae J, Lee H, Yang K, Park Y. Enhancement of antitumor immunity by combination of anti-CTLA-4 antibody and radioimmunotherapy through the suppression of Tregs. Oncol Lett. 2017;13:3781-3786 pubmed publisher

Ma S, Wan X, Deng Z, Shi L, Hao C, Zhou Z, et al. Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs. J Exp Med. 2017;214:1471-1491 pubmed publisher

Fujiu K, Shibata M, Nakayama Y, Ogata F, Matsumoto S, Noshita K, et al. A heart-brain-kidney network controls adaptation to cardiac stress through tissue macrophage activation. Nat Med. 2017;23:611-622 pubmed publisher

Olson O, Kim H, Quail D, Foley E, Joyce J. Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents. Cell Rep. 2017;19:101-113 pubmed publisher

Zhang C, Wang S, Li J, Zhang W, Zheng L, Yang C, et al. The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury. Cell Death Dis. 2017;8:e2695 pubmed publisher

Solhjou Z, Uehara M, Bahmani B, Maarouf O, Ichimura T, Brooks C, et al. Novel Application of Localized Nanodelivery of Anti-Interleukin-6 Protects Organ Transplant From Ischemia-Reperfusion Injuries. Am J Transplant. 2017;17:2326-2337 pubmed publisher

Kostarnoy A, Gancheva P, Lepenies B, Tukhvatulin A, Dzharullaeva A, Polyakov N, et al. Receptor Mincle promotes skin allergies and is capable of recognizing cholesterol sulfate. Proc Natl Acad Sci U S A. 2017;114:E2758-E2765 pubmed publisher

Samarasinghe A, Melo R, Duan S, LeMessurier K, Liedmann S, Surman S, et al. Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus. J Immunol. 2017;198:3214-3226 pubmed publisher

Itoh Nakadai A, Matsumoto M, Kato H, Sasaki J, Uehara Y, Sato Y, et al. A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors. Cell Rep. 2017;18:2401-2414 pubmed publisher

Pu Q, Gan C, Li R, Li Y, Tan S, Li X, et al. Atg7 Deficiency Intensifies Inflammasome Activation and Pyroptosis in Pseudomonas Sepsis. J Immunol. 2017;198:3205-3213 pubmed publisher

Zheng Q, Li X, Cheng X, Cui T, Zhuo Y, Ma W, et al. Granulocyte-macrophage colony-stimulating factor increases tumor growth and angiogenesis directly by promoting endothelial cell function and indirectly by enhancing the mobilization and recruitment of proangiogenic granulocytes. Tumour Biol. 2017;39:1010428317692232 pubmed publisher

Watkins H, Rappazzo C, Higgins J, Sun X, Brock N, Chau A, et al. Safe Recombinant Outer Membrane Vesicles that Display M2e Elicit Heterologous Influenza Protection. Mol Ther. 2017;25:989-1002 pubmed publisher

Fang Y, Wang B, Zhao Y, Xiao Z, Li J, Cui Y, et al. Collagen scaffold microenvironments modulate cell lineage commitment for differentiation of bone marrow cells into regulatory dendritic cells. Sci Rep. 2017;7:42049 pubmed publisher

Daria A, Colombo A, Llovera G, Hampel H, Willem M, Liesz A, et al. Young microglia restore amyloid plaque clearance of aged microglia. EMBO J. 2017;36:583-603 pubmed publisher

Ceeraz S, Sergent P, Plummer S, Schned A, Pechenick D, Burns C, et al. VISTA Deficiency Accelerates the Development of Fatal Murine Lupus Nephritis. Arthritis Rheumatol. 2017;69:814-825 pubmed publisher

Pomeroy E, Lee L, Lee R, Schirm D, Temiz N, Ma J, et al. Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia. Oncogene. 2017;36:3263-3273 pubmed publisher

Yang L, Liu C, Zheng H, Kanekiyo T, Atagi Y, Jia L, et al. LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways. J Neuroinflammation. 2016;13:304 pubmed

Ge L, Vujanovic N. Soluble TNF Regulates TACE via AP-2? Transcription Factor in Mouse Dendritic Cells. J Immunol. 2017;198:417-427 pubmed

Lim Y, Yi M, Choi J, Lee J, Han J, Jo S, et al. Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections. Sci Rep. 2016;6:37211 pubmed publisher

Taguchi K, Okada A, Hamamoto S, Unno R, Moritoki Y, Ando R, et al. M1/M2-macrophage phenotypes regulate renal calcium oxalate crystal development. Sci Rep. 2016;6:35167 pubmed publisher

Diny N, Hou X, Barin J, Chen G, Talor M, Schaub J, et al. Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart. Eur J Immunol. 2016;46:2749-2760 pubmed publisher

Sato Kasai M, Kato T, Ohgidani M, Mizoguchi Y, Sagata N, Inamine S, et al. Aripiprazole inhibits polyI:C-induced microglial activation possibly via TRPM7. Schizophr Res. 2016;178:35-43 pubmed publisher

Nam S, Kang K, Cha J, Kim J, Lee H, Kim Y, et al. Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function. J Leukoc Biol. 2016;100:1273-1284 pubmed

Achuthan A, Cook A, Lee M, Saleh R, Khiew H, Chang M, et al. Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation. J Clin Invest. 2016;126:3453-66 pubmed publisher

Myles I, Zhao M, Nardone G, Olano L, Reckhow J, Saleem D, et al. CD8+ T cells produce a dialyzable antigen-specific activator of dendritic cells. J Leukoc Biol. 2017;101:307-320 pubmed publisher

Kim S, Lim E, Yoon Y, Ahn Y, Park E, Kim H, et al. Liver X receptor and STAT1 cooperate downstream of Gas6/Mer to induce anti-inflammatory arginase 2 expression in macrophages. Sci Rep. 2016;6:29673 pubmed publisher

Pfaender S, Grabski E, Detje C, Riebesehl N, Lienenklaus S, Steinmann E, et al. Hepatitis C Virus Stimulates Murine CD8α-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner. PLoS Pathog. 2016;12:e1005736 pubmed publisher

Schülke S, Vogel L, Junker A, Hanschmann K, Flaczyk A, Vieths S, et al. A Fusion Protein Consisting of the Vaccine Adjuvant Monophosphoryl Lipid A and the Allergen Ovalbumin Boosts Allergen-Specific Th1, Th2, and Th17 Responses In Vitro. J Immunol Res. 2016;2016:4156456 pubmed publisher

Ersching J, Basso A, Kalich V, Bortoluci K, Rodrigues M. A Human Trypanosome Suppresses CD8+ T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4+ Foxp3+ T Cells. PLoS Pathog. 2016;12:e1005698 pubmed publisher

Suzuki K, Tsunoda H, Omiya R, Matoba K, Baba T, Suzuki S, et al. Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies. PLoS ONE. 2016;11:e0156719 pubmed publisher

Maji M, Mazumder S, Bhattacharya S, Choudhury S, Sabur A, Shadab M, et al. A Lipid Based Antigen Delivery System Efficiently Facilitates MHC Class-I Antigen Presentation in Dendritic Cells to Stimulate CD8(+) T Cells. Sci Rep. 2016;6:27206 pubmed publisher

Elshikha A, Lu Y, Chen M, Akbar M, Zeumer L, Ritter A, et al. Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus. PLoS ONE. 2016;11:e0156583 pubmed publisher

Ding L, Liu T, Wu Z, Hu B, Nakashima T, Ullenbruch M, et al. Bone Marrow CD11c+ Cell-Derived Amphiregulin Promotes Pulmonary Fibrosis. J Immunol. 2016;197:303-12 pubmed publisher

Wirsdörfer F, Bangen J, Pastille E, Schmitz D, Flohe S, Schumak B, et al. Dendritic Cell-Like Cells Accumulate in Regenerating Murine Skeletal Muscle after Injury and Boost Adaptive Immune Responses Only upon a Microbial Challenge. PLoS ONE. 2016;11:e0155870 pubmed publisher

Zhao R, Liang D, Sun D. Blockade of Extracellular ATP Effect by Oxidized ATP Effectively Mitigated Induced Mouse Experimental Autoimmune Uveitis (EAU). PLoS ONE. 2016;11:e0155953 pubmed publisher

Tukhvatulin A, Dzharullaeva A, Tukhvatulina N, Shcheblyakov D, Shmarov M, Dolzhikova I, et al. Powerful Complex Immunoadjuvant Based on Synergistic Effect of Combined TLR4 and NOD2 Activation Significantly Enhances Magnitude of Humoral and Cellular Adaptive Immune Responses. PLoS ONE. 2016;11:e0155650 pubmed publisher

Slatter T, Wilson M, Tang C, Campbell H, Ward V, Young V, et al. Antitumor cytotoxicity induced by bone-marrow-derived antigen-presenting cells is facilitated by the tumor suppressor protein p53 via regulation of IL-12. Oncoimmunology. 2016;5:e1112941 pubmed

Shiraishi M, Shintani Y, Shintani Y, Ishida H, Saba R, Yamaguchi A, et al. Alternatively activated macrophages determine repair of the infarcted adult murine heart. J Clin Invest. 2016;126:2151-66 pubmed publisher

Ersching J, Vasconcelos J, Ferreira C, Caetano B, Machado A, Bruna Romero O, et al. The Combined Deficiency of Immunoproteasome Subunits Affects Both the Magnitude and Quality of Pathogen- and Genetic Vaccination-Induced CD8+ T Cell Responses to the Human Protozoan Parasite Trypanosoma cruzi. PLoS Pathog. 2016;12:e1005593 pubmed publisher

Torres D, Kohler A, Delbauve S, Caminschi I, Lahoud M, Shortman K, et al. IL-12p40/IL-10 Producing preCD8?/Clec9A+ Dendritic Cells Are Induced in Neonates upon Listeria monocytogenes Infection. PLoS Pathog. 2016;12:e1005561 pubmed publisher

Wortham B, Eppert B, Flury J, Garcia S, Donica W, Osterburg A, et al. Cutting Edge: CLEC5A Mediates Macrophage Function and Chronic Obstructive Pulmonary Disease Pathologies. J Immunol. 2016;196:3227-31 pubmed publisher

Wang Y, Su L, Morin M, Jones B, Whitby L, Surakattula M, et al. TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc Natl Acad Sci U S A. 2016;113:E884-93 pubmed publisher

Wertz I, Newton K, Seshasayee D, Kusam S, Lam C, Zhang J, et al. Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Nature. 2015;528:370-5 pubmed publisher

Chessa F, Mathow D, Wang S, Hielscher T, Atzberger A, Porubsky S, et al. The renal microenvironment modifies dendritic cell phenotype. Kidney Int. 2016;89:82-94 pubmed publisher

Talaei N, Yu T, Manion K, Bremner R, Wither J. Identification of the SLAM Adapter Molecule EAT-2 as a Lupus-Susceptibility Gene That Acts through Impaired Negative Regulation of Dendritic Cell Signaling. J Immunol. 2015;195:4623-31 pubmed publisher

Agrawal K, Kale S, Arora N. Protease activity of Per a 10 potentiates Th2 polarization by increasing IL-23 and OX40L. Eur J Immunol. 2015;45:3375-85 pubmed publisher

Sahin E, Brunner J, Kral J, Kuttke M, Hanzl L, Datler H, et al. Loss of Phosphatase and Tensin Homolog in APCs Impedes Th17-Mediated Autoimmune Encephalomyelitis. J Immunol. 2015;195:2560-70 pubmed publisher

Vashishta M, Khan N, Mehto S, Sehgal D, Natarajan K. Pneumococal Surface Protein A (PspA) Regulates Programmed Death Ligand 1 Expression on Dendritic Cells in a Toll-Like Receptor 2 and Calcium Dependent Manner. PLoS ONE. 2015;10:e0133601 pubmed publisher

Noman M, Janji B, Hu S, Wu J, Martelli F, Bronte V, et al. Tumor-Promoting Effects of Myeloid-Derived Suppressor Cells Are Potentiated by Hypoxia-Induced Expression of miR-210. Cancer Res. 2015;75:3771-87 pubmed publisher

Chen M, Liang D, Zuo A, Shao H, Kaplan H, Sun D. An A2B Adenosine Receptor Agonist Promotes Th17 Autoimmune Responses in Experimental Autoimmune Uveitis (EAU) via Dendritic Cell Activation. PLoS ONE. 2015;10:e0132348 pubmed publisher

Ptaschinski C, Mukherjee S, Moore M, Albert M, Helin K, Kunkel S, et al. RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo. PLoS Pathog. 2015;11:e1004978 pubmed publisher

Schumacher A, Denecke B, Braunschweig T, Stahlschmidt J, Ziegler S, Brandenburg L, et al. Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy. J Hematol Oncol. 2015;8:64 pubmed publisher

Pamir N, Liu N, Irwin A, Becker L, Peng Y, Ronsein G, et al. Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion. J Biol Chem. 2015;290:14656-67 pubmed publisher

Gao F, Liu C, Guo J, Sun W, Xian L, Bai D, et al. Radiation-driven lipid accumulation and dendritic cell dysfunction in cancer. Sci Rep. 2015;5:9613 pubmed publisher

Wang H, Bei L, Shah C, Hu L, Eklund E. HoxA10 Terminates Emergency Granulopoiesis by Increasing Expression of Triad1. J Immunol. 2015;194:5375-87 pubmed publisher

Lee J, Martinez N, West K, Kornfeld H. Differential adjuvant activities of TLR7 and TLR9 agonists inversely correlate with nitric oxide and PGE2 production. PLoS ONE. 2015;10:e0123165 pubmed publisher

Chen Y, Zhang J, Lu Y, Wang L. Immunosuppression in early postnatal days induces persistent and allergen-specific immune tolerance to asthma in adult mice. PLoS ONE. 2015;10:e0122990 pubmed publisher

Raïch Regué D, Rosborough B, Watson A, McGeachy M, Turnquist H, Thomson A. mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo. J Immunol. 2015;194:4767-76 pubmed publisher

Liang X, Liu Y, Mei S, Zhang M, Xin J, Zhang Y, et al. MicroRNA-22 impairs anti-tumor ability of dendritic cells by targeting p38. PLoS ONE. 2015;10:e0121510 pubmed publisher

Liu X, Ren S, Ge C, Cheng K, Zenke M, Keating A, et al. Sca-1+Lin-CD117- mesenchymal stem/stromal cells induce the generation of novel IRF8-controlled regulatory dendritic cells through Notch-RBP-J signaling. J Immunol. 2015;194:4298-308 pubmed publisher

Noh K, Son K, Jung I, Kang T, Choi C, Park Y. Glycogen Synthase Kinase-3β (GSK-3β) Inhibition Enhances Dendritic Cell-based Cancer Vaccine Potency via Suppression of Interferon-γ-induced Indoleamine 2,3-Dioxygenase Expression. J Biol Chem. 2015;290:12394-402 pubmed publisher

Shan C, Shi L, Ding M, Zhu Y, Li X, Xu B, et al. Cytokine-induced killer cells co-cultured with dendritic cells loaded with the protein lysate produced by radiofrequency ablation induce a specific antitumor response. Oncol Lett. 2015;9:1549-1556 pubmed

Park M, Kim Y, Ryu J, Woo S, Ryu K. Immune suppressive effects of tonsil-derived mesenchymal stem cells on mouse bone-marrow-derived dendritic cells. Stem Cells Int. 2015;2015:106540 pubmed publisher

Nakano H, Moran T, Nakano K, Gerrish K, Bortner C, Cook D. Complement receptor C5aR1/CD88 and dipeptidyl peptidase-4/CD26 define distinct hematopoietic lineages of dendritic cells. J Immunol. 2015;194:3808-19 pubmed publisher

Anthony S, Howard M, Hailemichael Y, Overwijk W, Schluns K. Soluble interleukin-15 complexes are generated in vivo by type I interferon dependent and independent pathways. PLoS ONE. 2015;10:e0120274 pubmed publisher

Arieta Kuksin C, González Pérez G, Minter L. CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia. Blood. 2015;125:2087-94 pubmed publisher

Kim J, Kang M, Kim W, Han S, Kim H, Kim H, et al. Essential engagement of Toll-like receptor 2 in initiation of early protective Th1 response against rough variants of Mycobacterium abscessus. Infect Immun. 2015;83:1556-67 pubmed publisher

Mierzejewska K, Borkowska S, Suszyńska E, Suszynska M, Poniewierska Baran A, Maj M, et al. Hematopoietic stem/progenitor cells express several functional sex hormone receptors-novel evidence for a potential developmental link between hematopoiesis and primordial germ cells. Stem Cells Dev. 2015;24:927-37 pubmed publisher

Sun C, Schattgen S, Pisitkun P, Jorgensen J, Hilterbrand A, Wang L, et al. Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection. J Immunol. 2015;194:1819-31 pubmed publisher

Yao Y, Matsushima H, Ohtola J, Geng S, Lu R, Takashima A. Neutrophil priming occurs in a sequential manner and can be visualized in living animals by monitoring IL-1β promoter activation. J Immunol. 2015;194:1211-24 pubmed publisher

Miyawaki K, Arinobu Y, Iwasaki H, Kohno K, Tsuzuki H, Iino T, et al. CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: redefinition of murine common myeloid progenitor. Stem Cells. 2015;33:976-87 pubmed publisher

Jacob W, Rosenzweig D, Vázquez Martin C, Duce S, Cohen P. Decreased adipogenesis and adipose tissue in mice with inactivated protein phosphatase 5. Biochem J. 2015;466:163-76 pubmed publisher

Rožman S, Yousefi S, Oberson K, Kaufmann T, Benarafa C, Simon H. The generation of neutrophils in the bone marrow is controlled by autophagy. Cell Death Differ. 2015;22:445-56 pubmed publisher

Ye C, Choi J, Abraham S, Shankar P, Manjunath N. Targeting DNA vaccines to myeloid cells using a small peptide. Eur J Immunol. 2015;45:82-8 pubmed publisher

Salama A, Fichou N, Allard M, Dubreil L, De Beaurepaire L, Viel A, et al. MicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunity. PLoS ONE. 2014;9:e106153 pubmed publisher

Pennati A, Deng J, Galipeau J. Maltose-binding protein fusion allows for high level bacterial expression and purification of bioactive mammalian cytokine derivatives. PLoS ONE. 2014;9:e106724 pubmed publisher

Ohm I, Alfsnes K, Belland Olsen M, Ranheim T, Sandanger Ø, Dahl T, et al. Toll-like receptor 9 mediated responses in cardiac fibroblasts. PLoS ONE. 2014;9:e104398 pubmed publisher

Sahin E, Haubenwallner S, Kuttke M, Kollmann I, Halfmann A, Dohnal A, et al. Macrophage PTEN regulates expression and secretion of arginase I modulating innate and adaptive immune responses. J Immunol. 2014;193:1717-27 pubmed publisher

Boettcher S, Gerosa R, Radpour R, Bauer J, Ampenberger F, Heikenwalder M, et al. Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis. Blood. 2014;124:1393-403 pubmed publisher

Jung I, Shin S, Lee M, Kang T, Han H, Lee S, et al. Enhancement of tumor-specific T cell-mediated immunity in dendritic cell-based vaccines by Mycobacterium tuberculosis heat shock protein X. J Immunol. 2014;193:1233-45 pubmed publisher

Lu H, Lu N, Weng L, Yuan B, Liu Y, Zhang Z. DHX15 senses double-stranded RNA in myeloid dendritic cells. J Immunol. 2014;193:1364-72 pubmed publisher

Ilett E, Kottke T, Donnelly O, Thompson J, Willmon C, Diaz R, et al. Cytokine conditioning enhances systemic delivery and therapy of an oncolytic virus. Mol Ther. 2014;22:1851-63 pubmed publisher

Satchidanandam V, Kumar N, Jumani R, Challu V, Elangovan S, Khan N. The glycosylated Rv1860 protein of Mycobacterium tuberculosis inhibits dendritic cell mediated TH1 and TH17 polarization of T cells and abrogates protective immunity conferred by BCG. PLoS Pathog. 2014;10:e1004176 pubmed publisher

Wu L, Ong S, Talor M, Barin J, Baldeviano G, Kass D, et al. Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy. J Exp Med. 2014;211:1449-64 pubmed publisher

Miller I, Didier S, Murray D, Turner T, Issaivanan M, Ruggieri R, et al. Semapimod sensitizes glioblastoma tumors to ionizing radiation by targeting microglia. PLoS ONE. 2014;9:e95885 pubmed publisher

Nagareddy P, Kraakman M, Masters S, Stirzaker R, Gorman D, Grant R, et al. Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity. Cell Metab. 2014;19:821-35 pubmed publisher

Noman M, Desantis G, Janji B, Hasmim M, Karray S, Dessen P, et al. PD-L1 is a novel direct target of HIF-1?, and its blockade under hypoxia enhanced MDSC-mediated T cell activation. J Exp Med. 2014;211:781-90 pubmed publisher

Spoerl S, Mathew N, Bscheider M, Schmitt Graeff A, Chen S, Mueller T, et al. Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease. Blood. 2014;123:3832-42 pubmed publisher

Tseng J, Yang C, Liang S, Liu R, Yang S, Lin J, et al. Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases. Clin Cancer Res. 2014;20:2885-97 pubmed publisher

Shibata T, Habiel D, Coelho A, Kunkel S, Lukacs N, Hogaboam C. Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma. J Immunol. 2014;192:3569-81 pubmed publisher

Park M, Cho M, Kang S, Park H, Kim D, Yu H. Acanthamoeba protease activity promotes allergic airway inflammation via protease-activated receptor 2. PLoS ONE. 2014;9:e92726 pubmed publisher

Moraes Vieira P, Yore M, Dwyer P, Syed I, Aryal P, Kahn B. RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance. Cell Metab. 2014;19:512-26 pubmed publisher

Macmillan C, Doucette C, Warford J, Furlong S, Hoskin D, Easton A. Murine experimental autoimmune encephalomyelitis is diminished by treatment with the angiogenesis inhibitors B20-4.1.1 and angiostatin (K1-3). PLoS ONE. 2014;9:e89770 pubmed publisher

Taguchi K, Okada A, Kitamura H, Yasui T, Naiki T, Hamamoto S, et al. Colony-stimulating factor-1 signaling suppresses renal crystal formation. J Am Soc Nephrol. 2014;25:1680-97 pubmed publisher

Vangundy Z, Guerau de Arellano M, Baker J, Strange H, Olivo Marston S, Muth D, et al. Continuous retinoic acid induces the differentiation of mature regulatory monocytes but fails to induce regulatory dendritic cells. BMC Immunol. 2014;15:8 pubmed publisher

Robertson S, Lubick K, Freedman B, Carmody A, Best S. Tick-borne flaviviruses antagonize both IRF-1 and type I IFN signaling to inhibit dendritic cell function. J Immunol. 2014;192:2744-55 pubmed publisher

Kim E, Miyake B, Aggarwal M, Voetlause R, Griffith M, Zavazava N. Embryonic stem cell-derived haematopoietic progenitor cells down-regulate the CD3 ? chain on T cells, abrogating alloreactive T cells. Immunology. 2014;142:421-30 pubmed publisher

Winkelmann E, Widman D, Xia J, Johnson A, Van Rooijen N, Mason P, et al. Subcapsular sinus macrophages limit dissemination of West Nile virus particles after inoculation but are not essential for the development of West Nile virus-specific T cell responses. Virology. 2014;450-451:278-89 pubmed publisher

Ko H, Brady J, Ryg Cornejo V, Hansen D, Vremec D, Shortman K, et al. GM-CSF-responsive monocyte-derived dendritic cells are pivotal in Th17 pathogenesis. J Immunol. 2014;192:2202-9 pubmed publisher

Han J, Wui S, Kim K, Cho Y, Cho W, Lee N. Characterization of the structure and immunostimulatory activity of a vaccine adjuvant, de-O-acylated lipooligosaccharide. PLoS ONE. 2014;9:e85838 pubmed publisher

Li X, Jiang L, Chen L, Ding M, Guo H, Zhang W, et al. RIG-I modulates Src-mediated AKT activation to restrain leukemic stemness. Mol Cell. 2014;53:407-19 pubmed publisher

Chang Y, Olson J, Beasley F, Tung C, Zhang J, Crocker P, et al. Group B Streptococcus engages an inhibitory Siglec through sialic acid mimicry to blunt innate immune and inflammatory responses in vivo. PLoS Pathog. 2014;10:e1003846 pubmed publisher

Mikyšková R, Indrova M, Vlková V, Bieblova J, Simova J, Parackova Z, et al. DNA demethylating agent 5-azacytidine inhibits myeloid-derived suppressor cells induced by tumor growth and cyclophosphamide treatment. J Leukoc Biol. 2014;95:743-753 pubmed

Sturrock A, Mir Kasimov M, Baker J, Rowley J, Paine R. Key role of microRNA in the regulation of granulocyte macrophage colony-stimulating factor expression in murine alveolar epithelial cells during oxidative stress. J Biol Chem. 2014;289:4095-105 pubmed publisher

Chung Y, Zhang N, Wooten R. Borrelia burgdorferi elicited-IL-10 suppresses the production of inflammatory mediators, phagocytosis, and expression of co-stimulatory receptors by murine macrophages and/or dendritic cells. PLoS ONE. 2013;8:e84980 pubmed publisher

Nacionales D, Gentile L, Vanzant E, Lopez M, Cuenca A, Cuenca A, et al. Aged mice are unable to mount an effective myeloid response to sepsis. J Immunol. 2014;192:612-22 pubmed publisher

Garg S, Delaney C, Toubai T, Ghosh A, Reddy P, Banerjee R, et al. Aging is associated with increased regulatory T-cell function. Aging Cell. 2014;13:441-8 pubmed publisher

Buchta C, Bishop G. TRAF5 negatively regulates TLR signaling in B lymphocytes. J Immunol. 2014;192:145-50 pubmed publisher

Dowty M, Jesson M, Ghosh S, Lee J, Meyer D, Krishnaswami S, et al. Preclinical to clinical translation of tofacitinib, a Janus kinase inhibitor, in rheumatoid arthritis. J Pharmacol Exp Ther. 2014;348:165-73 pubmed publisher

Shah C, Bei L, Wang H, Platanias L, Eklund E. The leukemia-associated Mll-Ell oncoprotein induces fibroblast growth factor 2 (Fgf2)-dependent cytokine hypersensitivity in myeloid progenitor cells. J Biol Chem. 2013;288:32490-505 pubmed publisher

Benasciutti E, Mariani E, Oliva L, Scolari M, Perilli E, Barras E, et al. MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity. J Bone Miner Res. 2014;29:290-303 pubmed publisher

Kim J, Kim W, Choi H, Jang B, Lee K, Park J, et al. Mycobacterium tuberculosis RpfB drives Th1-type T cell immunity via a TLR4-dependent activation of dendritic cells. J Leukoc Biol. 2013;94:733-49 pubmed publisher

Jachetti E, Mazzoleni S, Grioni M, Ricupito A, Brambillasca C, Generoso L, et al. Prostate cancer stem cells are targets of both innate and adaptive immunity and elicit tumor-specific immune responses. Oncoimmunology. 2013;2:e24520 pubmed

Casella C, Mitchell T. Inefficient TLR4/MD-2 heterotetramerization by monophosphoryl lipid A. PLoS ONE. 2013;8:e62622 pubmed publisher

Toki S, Goleniewska K, Huckabee M, Zhou W, Newcomb D, Fitzgerald G, et al. PGI? signaling inhibits antigen uptake and increases migration of immature dendritic cells. J Leukoc Biol. 2013;94:77-88 pubmed publisher

Elcombe S, Naqvi S, Van Den Bosch M, MacKenzie K, Cianfanelli F, Brown G, et al. Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers. PLoS ONE. 2013;8:e60086 pubmed publisher

Ichihashi T, Satoh T, Sugimoto C, Kajino K. Emulsified phosphatidylserine, simple and effective peptide carrier for induction of potent epitope-specific T cell responses. PLoS ONE. 2013;8:e60068 pubmed publisher

Han W, Li H, Cai J, Gleaves L, Polosukhin V, Segal B, et al. NADPH oxidase limits lipopolysaccharide-induced lung inflammation and injury in mice through reduction-oxidation regulation of NF-?B activity. J Immunol. 2013;190:4786-94 pubmed publisher

Huang W, Bei L, Eklund E. Fas-associated phosphatase 1 (Fap1) influences ?catenin activity in myeloid progenitor cells expressing the Bcr-abl oncogene. J Biol Chem. 2013;288:12766-76 pubmed publisher

Lapid K, Itkin T, D Uva G, Ovadya Y, Ludin A, Caglio G, et al. GSK3? regulates physiological migration of stem/progenitor cells via cytoskeletal rearrangement. J Clin Invest. 2013;123:1705-17 pubmed publisher

Huang Q, Koessler R, Birkett R, Perlman H, Xing L, Pope R. TLR2 deletion promotes arthritis through reduction of IL-10. J Leukoc Biol. 2013;93:751-9 pubmed publisher

Napolitano A, Pittoni P, Beaudoin L, Lehuen A, Voehringer D, MacDonald H, et al. Functional education of invariant NKT cells by dendritic cell tuning of SHP-1. J Immunol. 2013;190:3299-308 pubmed publisher

Gartlan K, Wee J, Demaria M, Nastovska R, Chang T, Jones E, et al. Tetraspanin CD37 contributes to the initiation of cellular immunity by promoting dendritic cell migration. Eur J Immunol. 2013;43:1208-19 pubmed publisher

Kumar M, Roe K, Orillo B, Muruve D, Nerurkar V, Gale M, et al. Inflammasome adaptor protein Apoptosis-associated speck-like protein containing CARD (ASC) is critical for the immune response and survival in west Nile virus encephalitis. J Virol. 2013;87:3655-67 pubmed publisher

Jang S, Smit J, Kallal L, Lukacs N. Respiratory syncytial virus infection modifies and accelerates pulmonary disease via DC activation and migration. J Leukoc Biol. 2013;94:5-15 pubmed publisher

Vermeer D, Spanos W, Vermeer P, Bruns A, Lee K, Lee J. Radiation-induced loss of cell surface CD47 enhances immune-mediated clearance of human papillomavirus-positive cancer. Int J Cancer. 2013;133:120-9 pubmed publisher

Xu Q, Chai S, Qian Y, Zhang M, Wang K. Breast regression protein-39 (BRP-39) promotes dendritic cell maturation in vitro and enhances Th2 inflammation in murine model of asthma. Acta Pharmacol Sin. 2012;33:1525-32 pubmed publisher

Munich S, Sobo Vujanovic A, Buchser W, Beer Stolz D, Vujanovic N. Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands. Oncoimmunology. 2012;1:1074-1083 pubmed

Jacome Galarza C, Lee S, Lorenzo J, Aguila H. Identification, characterization, and isolation of a common progenitor for osteoclasts, macrophages, and dendritic cells from murine bone marrow and periphery. J Bone Miner Res. 2013;28:1203-13 pubmed publisher

Charles J, Hsu L, Niemi E, Weiss A, Aliprantis A, Nakamura M. Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function. J Clin Invest. 2012;122:4592-605 pubmed publisher

Umeshappa C, Nanjundappa R, Xie Y, Freywald A, Xu Q, Xiang J. Differential requirements of CD4(+) T-cell signals for effector cytotoxic T-lymphocyte (CTL) priming and functional memory CTL development at higher CD8(+) T-cell precursor frequency. Immunology. 2013;138:298-306 pubmed publisher

Hou J, Liu Y, Liu Y, Shao Y. The MSHA strain of Pseudomonas aeruginosa activated TLR pathway and enhanced HIV-1 DNA vaccine immunoreactivity. PLoS ONE. 2012;7:e47724 pubmed publisher

Mun S, Won H, Hernandez P, Aguila H, Lee S. Deletion of CD74, a putative MIF receptor, in mice enhances osteoclastogenesis and decreases bone mass. J Bone Miner Res. 2013;28:948-59 pubmed publisher

Domingos Pereira S, Decrausaz L, Derré L, Bobst M, Romero P, Schiller J, et al. Intravaginal TLR agonists increase local vaccine-specific CD8 T cells and human papillomavirus-associated genital-tumor regression in mice. Mucosal Immunol. 2013;6:393-404 pubmed publisher

Freeman B, Hammarlund E, Raué H, Slifka M. Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A. 2012;109:9971-6 pubmed publisher

Noh K, Son K, Jung I, Kang H, Hwang S, Lee W, et al. Protein kinase C ? (PKC?)-extracellular signal-regulated kinase 1/2 (ERK1/2) signaling cascade regulates glycogen synthase kinase-3 (GSK-3) inhibition-mediated interleukin-10 (IL-10) expression in lipopolysaccharide (LPS)-induced endotoxemia. J Biol Chem. 2012;287:14226-33 pubmed publisher

Barin J, Baldeviano G, Talor M, Wu L, Ong S, Quader F, et al. Macrophages participate in IL-17-mediated inflammation. Eur J Immunol. 2012;42:726-36 pubmed publisher

Chen M, Forrester J, Xu H. Dysregulation in retinal para-inflammation and age-related retinal degeneration in CCL2 or CCR2 deficient mice. PLoS ONE. 2011;6:e22818 pubmed publisher

Kinzfogl J, Hangoc G, Broxmeyer H. Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells. Blood. 2011;118:565-75 pubmed publisher

Cook B, Liu S, Evans T. Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment. Blood. 2011;117:6489-97 pubmed publisher

Jung I, Noh K, Lee C, Chun S, Jeong S, Park J, et al. Oncostatin M induces dendritic cell maturation and Th1 polarization. Biochem Biophys Res Commun. 2010;394:272-8 pubmed publisher

Kallal L, Schaller M, Lindell D, Lira S, Lukacs N. CCL20/CCR6 blockade enhances immunity to RSV by impairing recruitment of DC. Eur J Immunol. 2010;40:1042-52 pubmed publisher

Fukui R, Saitoh S, Matsumoto F, Kozuka Hata H, Oyama M, Tabeta K, et al. Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing. J Exp Med. 2009;206:1339-50 pubmed publisher

Claudio E, Sønder S, Saret S, Carvalho G, Ramalingam T, Wynn T, et al. The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation. J Immunol. 2009;182:1617-30 pubmed

Beck J, Preston A, Wilcoxen S, Morris S, Sturrock A, Paine R. Critical roles of inflammation and apoptosis in improved survival in a model of hyperoxia-induced acute lung injury in Pneumocystis murina-infected mice. Infect Immun. 2009;77:1053-60 pubmed publisher

Liu Q, Cheng L, Yi L, Zhu N, Wood A, Changpriroa C, et al. p47phox deficiency induces macrophage dysfunction resulting in progressive crystalline macrophage pneumonia. Am J Pathol. 2009;174:153-63 pubmed publisher

Novitskiy S, Ryzhov S, Zaynagetdinov R, Goldstein A, Huang Y, Tikhomirov O, et al. Adenosine receptors in regulation of dendritic cell differentiation and function. Blood. 2008;112:1822-31 pubmed publisher

Guo B, Chang E, Cheng G. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J Clin Invest. 2008;118:1680-90 pubmed publisher

Lau A, Biester S, Cornall R, Forrester J. Lipopolysaccharide-activated IL-10-secreting dendritic cells suppress experimental autoimmune uveoretinitis by MHCII-dependent activation of CD62L-expressing regulatory T cells. J Immunol. 2008;180:3889-99 pubmed

Shojaei F, Wu X, ZHONG C, Yu L, Liang X, Yao J, et al. Bv8 regulates myeloid-cell-dependent tumour angiogenesis. Nature. 2007;450:825-31 pubmed

Matsumoto K, Fukuyama S, Eguchi Tsuda M, Nakano T, Matsumoto T, Matsumura M, et al. B7-DC induced by IL-13 works as a feedback regulator in the effector phase of allergic asthma. Biochem Biophys Res Commun. 2008;365:170-5 pubmed

Tian F, Grimaldo S, Fujita M, Fugita M, Cutts J, Vujanovic N, et al. The endothelial cell-produced antiangiogenic cytokine vascular endothelial growth inhibitor induces dendritic cell maturation. J Immunol. 2007;179:3742-51 pubmed

Gaudreau S, Guindi C, Ménard M, Besin G, Dupuis G, Amrani A. Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells. J Immunol. 2007;179:3638-47 pubmed

Perri S, Annabi B, Galipeau J. Angiostatin inhibits monocyte/macrophage migration via disruption of actin cytoskeleton. FASEB J. 2007;21:3928-36 pubmed

Fritz J, Le Bourhis L, Sellge G, Magalhaes J, Fsihi H, Kufer T, et al. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity. 2007;26:445-59 pubmed

Koya R, Kimura T, Ribas A, Rozengurt N, Lawson G, Faure Kumar E, et al. Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines. Mol Ther. 2007;15:971-80 pubmed

Sugiyama K, Shirai R, Mukae H, Ishimoto H, Nagata T, Sakamoto N, et al. Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells. Clin Exp Immunol. 2007;147:540-6 pubmed

Kurooka M, Kaneda Y. Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells. Cancer Res. 2007;67:227-36 pubmed

Rafei M, Wu J, Annabi B, Lejeune L, Francois M, Galipeau J. A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex. Blood. 2007;109:2234-42 pubmed

Kim S, Nguyen A, Gao J, Murphy P, Mansfield B, Chou J. Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions. J Biol Chem. 2006;281:28794-801 pubmed

Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, et al. Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation. Biochem Biophys Res Commun. 2006;345:1122-30 pubmed

Reed J, Clegg D, Smith K, Tolod Richer E, Matter E, Picard L, et al. GM-CSF action in the CNS decreases food intake and body weight. J Clin Invest. 2005;115:3035-44 pubmed

Wada A, Tada Y, Shimozato O, Takiguchi Y, Tatsumi K, Kuriyama T, et al. Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines. Anticancer Res. 2005;25:299-303 pubmed

Dikov M, Ohm J, Ray N, Tchekneva E, Burlison J, Moghanaki D, et al. Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation. J Immunol. 2005;174:215-22 pubmed

Borg C, Jalil A, Laderach D, Maruyama K, Wakasugi H, Charrier S, et al. NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs. Blood. 2004;104:3267-75 pubmed

Abedi M, Greer D, Colvin G, Demers D, Dooner M, Harpel J, et al. Robust conversion of marrow cells to skeletal muscle with formation of marrow-derived muscle cell colonies: a multifactorial process. Exp Hematol. 2004;32:426-34 pubmed

Bouis D, Popova T, Takashima A, Norgard M. Dendritic cells phagocytose and are activated by Treponema pallidum. Infect Immun. 2001;69:518-28 pubmed

Gabrilovich D, Ishida T, Nadaf S, Ohm J, Carbone D. Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function. Clin Cancer Res. 1999;5:2963-70 pubmed