Recombinant Human SUMO1 AMC Protein, CF | R&D Systems UL-551-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human SUMO1 AMC Protein, CF

catalog :

UL-551-050

quantity :

50 ug

price :

335 USD

citations: 5

Reference
Paudel P, Zhang Q, Leung C, Greenberg H, Guo Y, Chern Y, et al. Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X. Proc Natl Acad Sci U S A. 2019;116:7288-7297 pubmed publisher
Rodriguez Castaneda F, Lemma R, Cuervo I, Bengtsen M, Moen L, Ledsaak M, et al. The SUMO protease SENP1 and the chromatin remodeler CHD3 interact and jointly affect chromatin accessibility and gene expression. J Biol Chem. 2018;293:15439-15454 pubmed publisher
Lapaquette P, Fritah S, Lhocine N, Andrieux A, Nigro G, Mounier J, et al. Shigella entry unveils a calcium/calpain-dependent mechanism for inhibiting sumoylation. elife. 2017;6: pubmed publisher
Urbanus M, Quaile A, Stogios P, Morar M, Rao C, Di Leo R, et al. Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Mol Syst Biol. 2016;12:893 pubmed publisher
Liang Q, Dexheimer T, Zhang P, Rosenthal A, Villamil M, You C, et al. A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. Nat Chem Biol. 2014;10:298-304 pubmed publisher

product information

brand :

R&D Systems

master code :

UL-551

SKU :

UL-551-050

product name :

Recombinant Human SUMO1 AMC Protein, CF

description :

The Recombinant Human SUMO1 AMC Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human SUMO1 AMC Protein, CF has been validated for the following applications: Enzyme Activity.

target :

SUMO1

category :

Proteins and Enzymes

sizes available :

50 ug

buffer :

1.13 mg/ml (100 µM) in 50 mM HEPES pH 7.5, 100 mM NaCl

conjugate :

7-Amino-4-Methyl Coumarin

purity :

>95%, by HPLC.

species :

Human

theoretical molecular weight :

11 kDa

gene symbol :

SUMO1

details of functionality :

Recombinant Human SUMO1 AMC is a fluorogenic substrate for some SUMO-specific isopeptidases. Release of AMC fluorescence can be monitored with an excitation wavelength of 345 nM and an emission wavelength of 445 nM. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human SUMO1 AMC concentration of 0.1-1 µM.

accessionNumbers :

P63165

applications :

Enzyme Activity

extended description :

This item is in process of being discontinued.

source :

E. coli-derived Recombinant Human SUMO1 AMC Protein, CF

USD :

319

USD 2023 :

335 USD

product details :

This item is in process of being discontinued.

alt names :

DAP1, GAP modifying protein 1, GAP-modifying protein 1, GMP1SMT3CSMT3H3OFC10UBL1PIC1, PIC1, SENP2, sentrin, small ubiquitin-related modifier 1, SMT3, SMT3 homolog 3, SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae), SMT3 suppressor of mif two 3 homolog 1 (yeast), Smt3C, SMT3H3, SUMO-1, Ubiquitin-homology domain protein PIC1, ubiquitin-like 1 (sentrin), Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1, UBL1

storage :

Protect from light. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.