AQUApure Tetra-Ub Chains (K11-linked) Protein, CF | R&D Systems UC-45-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

AQUApure Tetra-Ub Chains (K11-linked) Protein, CF

catalog :

UC-45-025

quantity :

25 ug

more info or order :

R&D Systems product webpage

citations: 5

Reference
Bolhuis D, Fleifel D, Bonacci T, Wang X, Mouery B, Cook J, et al. USP37 prevents unscheduled replisome unloading through MCM complex deubiquitination. bioRxiv. 2024;: pubmed publisher
Deng M, Lin J, Nowsheen S, Liu T, Zhao Y, Villalta P, et al. Extracellular matrix stiffness determines DNA repair efficiency and cellular sensitivity to genotoxic agents. Sci Adv. 2020;6: pubmed publisher
Yang S, Liu L, Cao C, Song N, Wang Y, Ma S, et al. USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization. Nat Commun. 2018;9:1285 pubmed publisher
Haahr P, Borgermann N, Guo X, Typas D, Achuthankutty D, Hoffmann S, et al. ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability. Mol Cell. 2018;70:165-174.e6 pubmed publisher
Park J, Kwon M, Kim E, Lee H, Song E. USP35 regulates mitotic progression by modulating the stability of Aurora B. Nat Commun. 2018;9:688 pubmed publisher

image

image 1 :

product information

master code :

UC-45

SKU :

UC-45-025

product name :

AQUApure Tetra-Ub Chains (K11-linked) Protein, CF

unit size :

25 ug

description :

The AQUApure Tetra-Ub Chains (K11-linked) Protein, CF from R&D Systems is derived from E. coli. The AQUApure Tetra-Ub Chains (K11-linked) Protein, CF has been validated for the following applications: Bioactivity.

target :

Tetra-Ubiquitin

category :

Proteins and Enzymes

buffer :

Supplied as a solution in deionized water.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain.

species :

Human

theoretical molecular weight :

34 kDa

gene symbol :

UBB

details of functionality :

Reaction conditions will need to be optimized for each specific application. IMPORTANT: Heating this product in SDS-PAGE buffer or terminating reactions containing this product with heated SDS-PAGE buffer could lead to unexpected, high apparent molecular weight banding or smearing on gels that is not representative of product purity. For optimal results, we recommend incubation in SDS-PAGE buffer + DTT at 40 ░C for 20 minutes prior to gel electrophoresis.

accessionNumbers :

P0CG47.1

applications :

Bioactivity

source long :

E. coli -derived human Tetra-Ubiquitin protein Met1 - Gly76

source short :

E. coli

extended description :

Will be discontinued when existing inventory is gone.

product details :

Will be discontinued when existing inventory is gone.

alt names :

HEL-S-50, TetraUbiquitin, Ub4, UBB, ubiquitin B

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage