Recombinant Human Ubiquitin Rhodamine 110 Protein, CF | R&D Systems U-555-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Ubiquitin Rhodamine 110 Protein, CF

catalog :

U-555-050

quantity :

50 ug

price :

410 USD

more info or order :

R&D Systems product webpage

citations: 12

Reference
Mali S, Silva R, Gong Z, Cronce M, Vo U, Vuong C, et al. SARS-CoV-2 papain-like protease activates nociceptors to drive sneeze and pain. bioRxiv. 2024;: pubmed publisher
Zhang X, Feng N, Liu Y, Guo Q, Wang J, Bai Y, et al. Neuroinflammation inhibition by small-molecule targeting USP7 noncatalytic domain for neurodegenerative disease therapy. Sci Adv. 2022;8:eabo0789 pubmed publisher
Hewitt C, Das C, Flaherty D. Rational Development and Characterization of a Ubiquitin Variant with Selectivity for Ubiquitin C-Terminal Hydrolase L3. Biomolecules. 2022;12: pubmed publisher
Tsefou E, Walker A, Clark E, Hicks A, Luft C, Takeda K, et al. Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches. Biochem J. 2021;478:4099-4118 pubmed publisher
Selvaraju K, Mofers A, Pellegrini P, Salomonsson J, Ahlner A, Morad V, et al. Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system. Sci Rep. 2019;9:9841 pubmed publisher
Teyra J, Singer A, Schmitges F, Jaynes P, Kit Leng Lui S, Polyak M, et al. Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure. 2019;27:590-605.e5 pubmed publisher
Abu El Rub E, Sequiera G, Sareen N, Yan W, Moudgil M, Sabbir M, et al. Hypoxia-induced 26S proteasome dysfunction increases immunogenicity of mesenchymal stem cells. Cell Death Dis. 2019;10:90 pubmed publisher
Haahr P, Borgermann N, Guo X, Typas D, Achuthankutty D, Hoffmann S, et al. ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability. Mol Cell. 2018;70:165-174.e6 pubmed publisher
Hewings D, Heideker J, Ma T, AhYoung A, El Oualid F, Amore A, et al. Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes. Nat Commun. 2018;9:1162 pubmed publisher
Turnbull A, Ioannidis S, Krajewski W, Pinto Fernandez A, Heride C, Martin A, et al. Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature. 2017;550:481-486 pubmed publisher
Zhang W, Sartori M, Makhnevych T, Federowicz K, Dong X, Liu L, et al. Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10. J Mol Biol. 2017;429:3546-3560 pubmed publisher
Lee J, Lee M. Isolation and Characterization of RNA Aptamers against a Proteasome-Associated Deubiquitylating Enzyme UCH37. Chembiochem. 2017;18:171-175 pubmed publisher

product information

master code :

U-555

SKU :

U-555-050

product name :

Recombinant Human Ubiquitin Rhodamine 110 Protein, CF

unit size :

50 ug

description :

The Recombinant Human Ubiquitin Rhodamine 110 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Ubiquitin Rhodamine 110 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Ubiquitin

category :

Proteins and Enzymes

buffer :

Supplied as a solution in DMSO.

conjugate :

Rhodamine 110

species :

Human

theoretical molecular weight :

8.9 kDa

gene symbol :

UBB

details of functionality :

Recombinant Human Ubiquitin-Rhodamine110 (R110) is ideal for use in assays requiring fluorescent detection. Optimal fluorescence at pH 8.0 is monitored with an excitation wavelength of 485 nM and an emission wavelength of 535 nM. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human Ubiquitin-Rhodamine110 (R110) concentration of 0.1-1 ╡M.

accessionNumbers :

P0CG47.1

applications :

Enzyme Activity

source long :

E. coli -derived human Ubiquitin protein Contains a C-terminal Rhodamine 110 (R110)

source short :

E. coli

USD :

410 USD

alt names :

RPS27A, UBA52, UBB, UBB ubiquitin B, UBC

storage :

Protect from light. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage