This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Ubiquitin Aldehyde Protein, CF
catalog :
U-201-050
quantity :
50 ug
price :
159 USD
citations: 17
Reference
Lee S, Garofano L, Ko A, D Angelo F, Frangaj B, Sommer D, et al. Regulated interaction of ID2 with the anaphase-promoting complex links progression through mitosis with reactivation of cell-type-specific transcription. Nat Commun. 2022;13:2089 pubmed publisher
Collins G, Sha Z, Kuo C, Erbil B, Goldberg A. Mammalian Ddi2 is a shuttling factor containing a retroviral protease domain that influences binding of ubiquitylated proteins and proteasomal degradation. J Biol Chem. 2022;298:101875 pubmed publisher
Shen C, Nayak A, Neitzel L, Adams A, Silver Isenstadt M, Sawyer L, et al. The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling. Nat Commun. 2021;12:5263 pubmed publisher
Simoneschi D, Róna G, Zhou N, Jeong Y, Jiang S, Milletti G, et al. CRL4AMBRA1 is a master regulator of D-type cyclins. Nature. 2021;592:789-793 pubmed publisher
Cathcart A, Bird G, Wales T, Herce H, Harvey E, Hauseman Z, et al. Targeting a helix-in-groove interaction between E1 and E2 blocks ubiquitin transfer. Nat Chem Biol. 2020;16:1218-1226 pubmed publisher
Xu W, Hua H, Chiu Y, Li G, Zhi H, Yu Z, et al. CD146 Regulates Growth Factor-Induced mTORC2 Activity Independent of the PI3K and mTORC1 Pathways. Cell Rep. 2019;29:1311-1322.e5 pubmed publisher
Lu G, Yi J, Gubas A, Wang Y, Wu Y, Ren Y, et al. Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation. Autophagy. 2019;:1-18 pubmed publisher
Schuyler S, Wu Y, Chen H, Ding Y, Lin C, Chu Y, et al. Peptide inhibitors of the anaphase promoting-complex that cause sensitivity to microtubule poison. PLoS ONE. 2018;13:e0198930 pubmed publisher
Lobanova E, Finkelstein S, Li J, Travis A, Hao Y, Klingeborn M, et al. Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration. Nat Commun. 2018;9:1738 pubmed publisher
de Moura T, Mozaffari Jovin S, Szabó C, Schmitzová J, Dybkov O, Cretu C, et al. Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol Cell. 2018;69:979-992.e6 pubmed publisher
Kuo C, Goldberg A. Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c. Proc Natl Acad Sci U S A. 2017;114:E3404-E3413 pubmed publisher
Houston K, Melvin A, Woss G, Fayer E, Waters M, Allbritton N. Development of β-Hairpin Peptides for the Measurement of SCF-Family E3 Ligase Activity in Vitro via Ornithine Ubiquitination. ACS Omega. 2017;2:1198-1206 pubmed publisher
Luo D, de Morrée A, Boutet S, Quach N, Natu V, Rustagi A, et al. Deltex2 represses MyoD expression and inhibits myogenic differentiation by acting as a negative regulator of Jmjd1c. Proc Natl Acad Sci U S A. 2017;114:E3071-E3080 pubmed publisher
Malonis R, Fu W, Jelcic M, Thompson M, Canter B, Tsikitis M, et al. RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling. J Biol Chem. 2017;292:7435-7451 pubmed publisher
Braganza A, Li J, Zeng X, Yates N, Dey N, Andrews J, et al. UBE3B Is a Calmodulin-regulated, Mitochondrion-associated E3 Ubiquitin Ligase. J Biol Chem. 2017;292:2470-2484 pubmed publisher
Chmura J, HEROLD K, Ruffin A, Atuobi T, Fabiyi Y, Mitchell A, et al. The Itch ubiquitin ligase is required for KSHV RTA induced vFLIP degradation. Virology. 2017;501:119-126 pubmed publisher
Wang R, Nan Y, Yu Y, Zhang Y. Porcine reproductive and respiratory syndrome virus Nsp1? inhibits interferon-activated JAK/STAT signal transduction by inducing karyopherin-?1 degradation. J Virol. 2013;87:5219-28 pubmed publisher
product information
brand :
R&D Systems
master code :
U-201
SKU :
U-201-050
product name :
Recombinant Human Ubiquitin Aldehyde Protein, CF
description :
The Recombinant Human Ubiquitin Aldehyde Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Ubiquitin Aldehyde Protein, CF has been validated for the following applications: Enzyme Activity.
target :
Ubiquitin
category :
Proteins and Enzymes
sizes available :
50 ug
buffer :
X mg/ml (X µM) as a solution in 50 mM HCl
conjugate :
Aldehyde
purity :
>96%, by HPLC.
species :
Human
theoretical molecular weight :
8.6 kDa
gene symbol :
UBB
details of functionality :
Add Recombinant Human Ubiquitin Aldehyde to in vitro assays to inhibit deubiquitinating enzymes. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human Ubiquitin Aldehyde concentration of 2-5 µM.
accessionNumbers :
P0CG47
applications :
Enzyme Activity
extended description :
This item is in process of being discontinued.
source :
E. coli-derived Recombinant Human Ubiquitin Aldehyde Protein, CF
USD :
151
USD 2023 :
159 USD
product details :
This item is in process of being discontinued.
alt names :
RPS27A, UBA52, UBB, UBB ubiquitin B, UBC
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.