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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Rat IL-6 Quantikine ELISA Kit
catalog :
PR6000B
quantity :
1 Pack (50 Plates)
citations: 116
Reference
Ayuob N, Shaker S, Hawuit E, Al Abbas N, Shaer N, Al Jaouni S, et al. L. Cucurbita pepo Alleviates Chronic Unpredictable Mild Stress via Modulation of Apoptosis, Neurogenesis, and Gliosis in Rat Hippocampus. Oxid Med Cell Longev. 2021;2021:6662649 pubmed publisher
Castel T, Theron M, Pichavant Rafini K, Guernec A, Joublin Delavat A, Gueguen B, et al. Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals?. Physiol Rep. 2021;9:e14933 pubmed publisher
Bashandy S, Ebaid H, Al Tamimi J, Ahmed Farid O, Omara E, Alhazza I. Melatonin Alleviated Potassium Dichromate-Induced Oxidative Stress and Reprotoxicity in Male Rats. Biomed Res Int. 2021;2021:3565360 pubmed publisher
Shcherbitskaia A, Vasilev D, Milyutina Y, Tumanova N, Mikhel A, Zalozniaia I, et al. Prenatal Hyperhomocysteinemia Induces Glial Activation and Alters Neuroinflammatory Marker Expression in Infant Rat Hippocampus. Cells. 2021;10: pubmed publisher
Sun J, Xin K, Leng C, Ge J. Down-regulation of SNHG16 alleviates the acute lung injury in sepsis rats through miR-128-3p/HMGB3 axis. BMC Pulm Med. 2021;21:191 pubmed publisher
Xu X, Wang D, Han Z, Wang B, Gao W, Fan Y, et al. A novel rat model of chronic subdural hematoma: Induction of inflammation and angiogenesis in the subdural space mimicking human-like features of progressively expanding hematoma. Brain Res Bull. 2021;172:108-119 pubmed publisher
Belinchón Romero I, Bellot P, Romero Pérez D, Herraiz Romero I, Marco F, Francés R, et al. Non-alcoholic fatty liver disease is associated with bacterial translocation and a higher inflammation response in psoriatic patients. Sci Rep. 2021;11:8593 pubmed publisher
Lee M, Chung T, B Y, Lee H, Lee J, Yune C, et al. The Need of Enterococcal Coverage in Severe Intra-Abdominal Infection: Evidence from Animal Study. J Clin Med. 2021;10: pubmed publisher
Jackson E, Mi Z, Gillespie D, Cheng D, Tofovic S. Long-Term Dipeptidyl Peptidase 4 Inhibition Worsens Hypertension and Renal and Cardiac Abnormalities in Obese Spontaneously Hypertensive Heart Failure Rats. J Am Heart Assoc. 2021;10:e020088 pubmed publisher
Gao H, Ma H, Gao M, Chen A, Zha S, Yan J. Long non-coding RNA GAS5 aggravates myocardial depression in mice with sepsis via the microRNA-449b/HMGB1 axis and the NF-κB signaling pathway. Biosci Rep. 2021;41: pubmed publisher
Elshemy M, Asem M, Allemailem K, Uto K, Ebara M, Nabil A. Antioxidative Capacity of Liver- and Adipose-Derived Mesenchymal Stem Cell-Conditioned Media and Their Applicability in Treatment of Type 2 Diabetic Rats. Oxid Med Cell Longev. 2021;2021:8833467 pubmed publisher
Zgórzyńska E, Stulczewski D, Dziedzic B, Su K, Walczewska A. Docosahexaenoic fatty acid reduces the pro-inflammatory response induced by IL-1β in astrocytes through inhibition of NF-κB and AP-1 transcription factor activation. BMC Neurosci. 2021;22:4 pubmed publisher
Zhang L, Zhang X, Wu T, Pan X, Wang Z. Isoflurane reduces septic neuron injury by HO‑1‑mediated abatement of inflammation and apoptosis. Mol Med Rep. 2021;23: pubmed publisher
Yao Z, Liu N, Zhu X, Wang L, Zhao Y, Liu Q, et al. Subanesthetic isoflurane abates ROS-activated MAPK/NF-κB signaling to repress ischemia-induced microglia inflammation and brain injury. Aging (Albany NY). 2020;12:26121-26139 pubmed publisher
Yaghouby F, Jang K, Hoang U, Asgari S, Vasudevan S. Sex Differences in Vagus Nerve Stimulation Effects on Rat Cardiovascular and Immune Systems. Front Neurosci. 2020;14:560668 pubmed publisher
Jia L, Xue K, Liu J, Habotta O, Hu L, Abdel Moneim A. Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways. Mediators Inflamm. 2020;2020:9419085 pubmed publisher
Li H, Fan L, Zhang Y, Cao Y, Liu X. SNHG16 aggravates chronic constriction injury-induced neuropathic pain in rats via binding with miR-124-3p and miR-141-3p to upregulate JAG1. Brain Res Bull. 2020;165:228-237 pubmed publisher
Wang X, Jiang M, He X, Zhang B, Peng W, Guo L. N‑acetyl cysteine inhibits the lipopolysaccharide‑induced inflammatory response in bone marrow mesenchymal stem cells by suppressing the TXNIP/NLRP3/IL‑1β signaling pathway. Mol Med Rep. 2020;22:3299-3306 pubmed publisher
Jiang M, Wang X, Wang P, Peng W, Zhang B, Guo L. Inhibitor of RAGE and glucose‑induced inflammation in bone marrow mesenchymal stem cells: Effect and mechanism of action. Mol Med Rep. 2020;22:3255-3262 pubmed publisher
Wang X. Inhibition of HtrA2 alleviates inflammatory response and cell apoptosis in lipopolysaccharide‑induced acute pneumonia in rats. Mol Med Rep. 2020;22:3127-3134 pubmed publisher
Sun W, Li A, Wang Z, Sun X, Dong M, Qi F, et al. Tetramethylpyrazine alleviates acute kidney injury by inhibiting NLRP3/HIF‑1α and apoptosis. Mol Med Rep. 2020;22:2655-2664 pubmed publisher
Huang C, Zhang W, Sun A, Zhang X, Guo J, Ji R, et al. Methane Ameliorates Lipopolysaccharide-Induced Acute Orchitis by Anti-inflammatory, Antioxidative, and Antiapoptotic Effects via Regulation of the PK2/PKR1 Pathway. Oxid Med Cell Longev. 2020;2020:7075836 pubmed publisher
Ming T, Yuan M, Kong Q, Huang Q, Xia Z, Wu X. Dexmedetomidine alleviates blunt chest trauma and hemorrhagic shock‑resuscitation‑induced acute lung injury through inhibiting the NLRP3 inflammasome. Mol Med Rep. 2020;22:2507-2515 pubmed publisher
Casanova Vallve N, Constantin Teodosiu D, Filer A, Hardy R, Greenhaff P, Chapman V. Skeletal muscle dysregulation in rheumatoid arthritis: Metabolic and molecular markers in a rodent model and patients. PLoS ONE. 2020;15:e0235702 pubmed publisher
Yuan F, Xie J, Liu K, Shan J, Sun Y, Ying W. Xanthan gum protects temporomandibular chondrocytes from IL‑1β through Pin1/NF‑κB signaling pathway. Mol Med Rep. 2020;22:1129-1136 pubmed publisher
Zhou B, Li L, Qiu X, Wu J, Xu L, Shao W. Long non-coding RNA ANRIL knockdown suppresses apoptosis and pro-inflammatory cytokines while enhancing neurite outgrowth via binding microRNA-125a in a cellular model of Alzheimer's disease. Mol Med Rep. 2020;22:1489-1497 pubmed publisher
Selim A, Nooh M, El Sawalhi M, Ismail N. Amelioration of age-related alterations in rat liver: Effects of curcumin C3 complex, Astragalus membranaceus and blueberry. Exp Gerontol. 2020;137:110982 pubmed publisher
Rohn F, Kordes C, Buschmann T, Reichert D, Wammers M, Poschmann G, et al. Impaired integrin α5 /β1 -mediated hepatocyte growth factor release by stellate cells of the aged liver. Aging Cell. 2020;19:e13131 pubmed publisher
Billah M, Ridiandries A, Allahwala U, Mudaliar H, Dona A, Hunyor S, et al. Remote Ischemic Preconditioning induces Cardioprotective Autophagy and Signals through the IL-6-Dependent JAK-STAT Pathway. Int J Mol Sci. 2020;21: pubmed publisher
Rahman T, Weickert C, Harms L, Meehan C, Schall U, Todd J, et al. Effect of Immune Activation during Early Gestation or Late Gestation on Inhibitory Markers in Adult Male Rats. Sci Rep. 2020;10:1982 pubmed publisher
Wang S, Zhou S, Xie X, Zhao L, Fu Y, Cai G, et al. Comparison of the acute toxicity, analgesic and anti-inflammatory activities and chemical composition changes in Rhizoma anemones Raddeanae caused by vinegar processing. BMC Complement Med Ther. 2020;20:7 pubmed publisher
van Waveren A, Duncan M, Coulson F, Fenning A. Moderate-intensity physical activity reduces systemic inflammation and maintains cardiorespiratory function following chronic particulate matter2.5 exposure in rats. Toxicol Rep. 2020;7:93-100 pubmed publisher
Zhang L, Ni S, Zhou X, Zhao Y. Hemorrhagic Shock Sensitized the Diaphragm to Ventilator-Induced Dysfunction through the Activation of IL-6/JAK/STAT Signaling-Mediated Autophagy in Rats. Mediators Inflamm. 2019;2019:3738409 pubmed publisher
Kuwabara W, Andrade Silva J, Pereira J, Scialfa J, Cipolla Neto J. Neutrophil activation causes tumor regression in Walker 256 tumor-bearing rats. Sci Rep. 2019;9:16524 pubmed publisher
El Agamy D, Naguib Y. CoQ10 ameliorates monosodium glutamate-induced alteration in detrusor activity and responsiveness in rats via anti-inflammatory, anti-oxidant and channel inhibiting mechanisms. BMC Urol. 2019;19:103 pubmed publisher
Hsiao C, Lin C, Hou Y, Ko J, Wang C. Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model. Int J Mol Sci. 2019;20: pubmed publisher
Hsiao C, Huang W, Cheng K, Lee C. Low-Energy Extracorporeal Shock Wave Therapy Ameliorates Kidney Function in Diabetic Nephropathy. Oxid Med Cell Longev. 2019;2019:8259645 pubmed publisher
Jedrzejewski T, Piotrowski J, Pawlikowska M, Wrotek S, Kozak W. Extract from Coriolus versicolor fungus partially prevents endotoxin tolerance development by maintaining febrile response and increasing IL-6 generation. J Therm Biol. 2019;83:69-79 pubmed publisher
Yang H, Kim M, Qiu J, Zhang T, Wu X, Jang D, et al. Rice Porridge Containing Welsh Onion Root Water Extract Alleviates Osteoarthritis-Related Pain Behaviors, Glucose Levels, and Bone Metabolism in Osteoarthritis-Induced Ovariectomized Rats. Nutrients. 2019;11: pubmed publisher
Zhao Q, Yang J, Liu B, Huang F, Li Y. Exosomes derived from mangiferin‑stimulated perivascular adipose tissue ameliorate endothelial dysfunction. Mol Med Rep. 2019;19:4797-4805 pubmed publisher
Kong Y, Gao Y, Lan D, Zhang Y, Zhan R, Liu M, et al. Trans-repression of NFκB pathway mediated by PPARγ improves vascular endothelium insulin resistance. J Cell Mol Med. 2019;23:216-226 pubmed publisher
Wang J, Li H, Ren Y, Yao Y, Hu J, Zheng M, et al. Local Delivery of β-Elemene Improves Locomotor Functional Recovery by Alleviating Endoplasmic Reticulum Stress and Reducing Neuronal Apoptosis in Rats with Spinal Cord Injury. Cell Physiol Biochem. 2018;49:595-609 pubmed publisher
Dutra M, Feliciano R, Jacinto K, Gouveia T, Brigidio E, Serra A, et al. Protective Role of UCP2 in Oxidative Stress and Apoptosis during the Silent Phase of an Experimental Model of Epilepsy Induced by Pilocarpine. Oxid Med Cell Longev. 2018;2018:6736721 pubmed publisher
Haihua C, Wei W, Kun H, Yuanli L, Fei L. Cobra Venom Factor-induced complement depletion protects against lung ischemia reperfusion injury through alleviating blood-air barrier damage. Sci Rep. 2018;8:10346 pubmed publisher
Chakraborty S, Islam S, Saha S, Ain R. Dexamethasone-induced Intra-Uterine Growth Restriction impacts NOSTRIN and its downstream effector genes in the rat mesometrial uterus. Sci Rep. 2018;8:8342 pubmed publisher
García Miguel M, Riquelme J, Norambuena Soto I, Morales P, Sanhueza Olivares F, Núñez Soto C, et al. Autophagy mediates tumor necrosis factor-α-induced phenotype switching in vascular smooth muscle A7r5 cell line. PLoS ONE. 2018;13:e0197210 pubmed publisher
Cavigelli S, Bao A, Bourne R, Caruso M, Caulfield J, Chen M, et al. Timing matters: the interval between acute stressors within chronic mild stress modifies behavioral and physiologic stress responses in male rats. Stress. 2018;21:453-463 pubmed publisher
Ahmed M, Kumar G, Gourevitch S, Levchenko T, Galun E, Torchilin V, et al. Radiofrequency ablation (RFA)-induced systemic tumor growth can be reduced by suppression of resultant heat shock proteins. Int J Hyperthermia. 2018;34:934-942 pubmed publisher
Hagan S, Fyfe M, Ofori Frimpong B, Oliver K, Foster M, Sirohi S, et al. Narrow Spectrum Kinase Inhibitors Demonstrate Promise for the Treatment of Dry Eye Disease and Other Ocular Inflammatory Disorders. Invest Ophthalmol Vis Sci. 2018;59:1443-1453 pubmed publisher
Baiyila B, He B, He G, Long T. Anti-inflammatory effect of Mongolian drug Naru-3 on traumatic spinal cord injury and its mechanism of action. J Int Med Res. 2018;46:2346-2358 pubmed publisher
Koerner J, Markova D, Schroeder G, Calio B, Shah A, Brooks C, et al. The local cytokine and growth factor response to recombinant human bone morphogenetic protein-2 (rhBMP-2) after spinal fusion. Spine J. 2018;18:1424-1433 pubmed publisher
Plaschke K, Do T, Uhle F, Brenner T, Weigand M, Kopitz J. Ablation of the Right Cardiac Vagus Nerve Reduces Acetylcholine Content without Changing the Inflammatory Response during Endotoxemia. Int J Mol Sci. 2018;19: pubmed publisher
Allam H, Masri A. The Potential Therapeutic Role of Peroxisome ProliferatorActivated Receptors Agonist in Preeclamptic Pregnant Rats. J Coll Physicians Surg Pak. 2018;28:31-35 pubmed publisher
Wu D, Lee S, Luo J, Xia H, Gushchina S, Richardson P, et al. Intraneural Injection of ATP Stimulates Regeneration of Primary Sensory Axons in the Spinal Cord. J Neurosci. 2018;38:1351-1365 pubmed publisher
Lania B, Morari J, Souza A, Silva M, de Almeida A, Veira Damiani G, et al. Topical use and systemic action of green and roasted coffee oils and ground oils in a cutaneous incision model in rats (Rattus norvegicus albinus). PLoS ONE. 2017;12:e0188779 pubmed publisher
Jeong J, Lee H, Kim J, Choi E, Hwang Bo H, Kim H, et al. Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate?induced osteoarthritis rats. Mol Med Rep. 2017;16:3841-3848 pubmed publisher
Chang J, Kim H, Jheon S, Lim C. Protective effects of GV1001 on myocardial ischemia‑reperfusion injury. Mol Med Rep. 2017;16:7315-7320 pubmed publisher
Fahrner R, Möller A, Press A, Kortgen A, Kiehntopf M, Rauchfuss F, et al. Short-term treatment with taurolidine is associated with liver injury. BMC Pharmacol Toxicol. 2017;18:61 pubmed publisher
Yan K, Shen Y. Aliskiren has chondroprotective efficacy in a rat model of osteoarthritis through suppression of the local renin-angiotensin system. Mol Med Rep. 2017;16:3965-3973 pubmed publisher
Ho D, Leong J, Crew R, Norret M, House M, Mark P, et al. Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation. Sci Rep. 2017;7:2866 pubmed publisher
Ahn M, Kim B, Kim H, Hwang J, Jung Y, Park K. Anti-aging effect and gene expression profiling of dung beetle glycosaminoglycan in aged rats. Biomater Res. 2017;21:5 pubmed publisher
Zhang X, Dong Y, Dong H, Zhang W, Li F. Investigation of the effect of phlomisoside F on complete Freund's adjuvant-induced arthritis. Exp Ther Med. 2017;13:710-716 pubmed publisher
Tan E, Shuh M, Francois Vaughan H, Sanders J, Cohen A. Negligible Oval Cell Proliferation Following Ischemia-Reperfusion Injury With and Without Partial Hepatectomy. Ochsner J. 2017;17:31-37 pubmed
Lu W, Albalawi F, Beckel J, Lim J, Laties A, Mitchell C. The P2X7 receptor links mechanical strain to cytokine IL-6 up-regulation and release in neurons and astrocytes. J Neurochem. 2017;141:436-448 pubmed publisher
Seo K, Choi J, Jung H, Yoo H, Joo J. The Effects of Remifentanil on Expression of High Mobility Group Box 1 in Septic Rats. J Korean Med Sci. 2017;32:542-551 pubmed publisher
Guo C, Bai L, Wu H, Yang J, Cai G, Wang X, et al. The analgesic effect of rolipram is associated with the inhibition of the activation of the spinal astrocytic JNK/CCL2 pathway in bone cancer pain. Int J Mol Med. 2016;38:1433-1442 pubmed publisher
Rosero O, Onody P, Kovacs T, Molnar D, Fülöp A, Lotz G, et al. Postconditioning: "Toll-erating" mesenteric ischemia-reperfusion injury?. Surgery. 2017;161:1004-1015 pubmed publisher
Sun J, Zhang S, Zhang X, Zhang X, Dong H, Qian Y. IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation. J Neuroinflammation. 2015;12:165 pubmed publisher
Shimizu S, Shimizu T, Tsounapi P, Higashi Y, Martin D, Nakamura K, et al. Effect of Silodosin, an Alpha1A-Adrenoceptor Antagonist, on Ventral Prostatic Hyperplasia in the Spontaneously Hypertensive Rat. PLoS ONE. 2015;10:e0133798 pubmed publisher
Ahmed M, Kumar G, Navarro G, Wang Y, Gourevitch S, Moussa M, et al. Systemic siRNA Nanoparticle-Based Drugs Combined with Radiofrequency Ablation for Cancer Therapy. PLoS ONE. 2015;10:e0128910 pubmed publisher
Garrido P, Ribeiro S, Fernandes J, Vala H, Bronze da Rocha E, Rocha Pereira P, et al. Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model. PLoS ONE. 2015;10:e0124048 pubmed publisher
Boittin F, Denis J, Mayol J, Martigne P, Raffin F, Coulon D, et al. The extent of irradiation-induced long-term visceral organ damage depends on cranial/brain exposure. PLoS ONE. 2015;10:e0122900 pubmed publisher
Chuffa L, Fioruci Fontanelli B, Mendes L, Ferreira Seiva F, Martinez M, Fávaro W, et al. Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer. BMC Cancer. 2015;15:34 pubmed publisher
Xiao W, Yin G, Fan Y, Qiu L, Cang X, Yu G, et al. Catalpol ameliorates sodium taurocholate-induced acute pancreatitis in rats via inhibiting activation of nuclear factor kappa B. Int J Mol Sci. 2014;15:11957-72 pubmed publisher
Shinozaki Y, Nomura M, Iwatsuki K, Moriyama Y, Gachet C, Koizumi S. Microglia trigger astrocyte-mediated neuroprotection via purinergic gliotransmission. Sci Rep. 2014;4:4329 pubmed publisher
Wang Z, Huang W, Zuo Z. Perioperative aspirin improves neurological outcome after focal brain ischemia possibly via inhibition of Notch 1 in rat. J Neuroinflammation. 2014;11:56 pubmed publisher
Bustamante M, Fernández Verdejo R, Jaimovich E, Buvinic S. Electrical stimulation induces IL-6 in skeletal muscle through extracellular ATP by activating Ca(2+) signals and an IL-6 autocrine loop. Am J Physiol Endocrinol Metab. 2014;306:E869-82 pubmed publisher
Wilson C, Mann J, Walsh M, Perrugoria M, Oakley F, Wright M, et al. Quiescent hepatic stellate cells functionally contribute to the hepatic innate immune response via TLR3. PLoS ONE. 2014;9:e83391 pubmed publisher
Ding N, Wang F, Xiao H, Xu L, She S. Mechanical ventilation enhances HMGB1 expression in an LPS-induced lung injury model. PLoS ONE. 2013;8:e74633 pubmed publisher
Nunes S, Soares E, Fernandes J, Viana S, Carvalho E, Pereira F, et al. Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker. Cardiovasc Diabetol. 2013;12:44 pubmed publisher
Leone E, Morelli E, Di Martino M, Amodio N, Foresta U, Gullà A, et al. Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth. Clin Cancer Res. 2013;19:2096-106 pubmed publisher
Aslami H, Beurskens C, de Beer F, Kuipers M, Roelofs J, Hegeman M, et al. A short course of infusion of a hydrogen sulfide-donor attenuates endotoxemia induced organ injury via stimulation of anti-inflammatory pathways, with no additional protection from prolonged infusion. Cytokine. 2013;61:614-21 pubmed publisher
Francque S, Laleman W, Verbeke L, Van Steenkiste C, Casteleyn C, Kwanten W, et al. Increased intrahepatic resistance in severe steatosis: endothelial dysfunction, vasoconstrictor overproduction and altered microvascular architecture. Lab Invest. 2012;92:1428-39 pubmed publisher
Wei T, Guo T, Li W, Hou S, Kingery W, Clark J. Keratinocyte expression of inflammatory mediators plays a crucial role in substance P-induced acute and chronic pain. J Neuroinflammation. 2012;9:181 pubmed
Frolkis I, Klein Y, Locker C, Adi N, Dahan E, Uretzsky G, et al. Vipera aspis venom reduces lethality and down-regulates tumor necrosis factor-alpha in a rat model of LPS-induced sepsis. Cytokine. 2010;49:319-24 pubmed publisher
Costello J, Higgins B, Contreras M, Chonghaile M, Hassett P, O Toole D, et al. Hypercapnic acidosis attenuates shock and lung injury in early and prolonged systemic sepsis. Crit Care Med. 2009;37:2412-20 pubmed publisher
Sánchez Lemus E, Benicky J, Pavel J, Saavedra J. In vivo Angiotensin II AT1 receptor blockade selectively inhibits LPS-induced innate immune response and ACTH release in rat pituitary gland. Brain Behav Immun. 2009;23:945-57 pubmed publisher
Yang S, Hu S, Chen J, Choudhry M, Rue L, Bland K, et al. Mechanism of hepatoprotection in proestrus female rats following trauma-hemorrhage: heme oxygenase-1-derived normalization of hepatic inflammatory responses. J Leukoc Biol. 2009;85:1015-26 pubmed publisher
Dominguez E, Rivat C, Pommier B, Mauborgne A, Pohl M. JAK/STAT3 pathway is activated in spinal cord microglia after peripheral nerve injury and contributes to neuropathic pain development in rat. J Neurochem. 2008;107:50-60 pubmed publisher
Wojcikowski J, Gołembiowska K, Daniel W. Regulation of liver cytochrome P450 by activation of brain dopaminergic system: physiological and pharmacological implications. Biochem Pharmacol. 2008;76:258-67 pubmed publisher
Johnson J, Cortez V, Kennedy S, Foley T, Hanson H, Fleshner M. Role of central beta-adrenergic receptors in regulating proinflammatory cytokine responses to a peripheral bacterial challenge. Brain Behav Immun. 2008;22:1078-86 pubmed publisher
Sanchez E, Singru P, Fekete C, Lechan R. Induction of type 2 iodothyronine deiodinase in the mediobasal hypothalamus by bacterial lipopolysaccharide: role of corticosterone. Endocrinology. 2008;149:2484-93 pubmed publisher
Xu J, Kim H, Ma Y, Zhao L, Zhai L, Kokorina N, et al. Trauma and hemorrhage-induced acute hepatic insulin resistance: dominant role of tumor necrosis factor-alpha. Endocrinology. 2008;149:2369-82 pubmed publisher
Choi G, Hofstra J, Roelofs J, Rijneveld A, Bresser P, van der Zee J, et al. Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats. Crit Care Med. 2008;36:204-10 pubmed
Wösten van Asperen R, Lutter R, Haitsma J, Merkus M, van Woensel J, van der Loos C, et al. ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin. Eur Respir J. 2008;31:363-71 pubmed
Stevenson C, Docx C, Webster R, Battram C, Hynx D, Giddings J, et al. Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation. Am J Physiol Lung Cell Mol Physiol. 2007;293:L1183-93 pubmed
Yu H, Hsieh Y, Suzuki T, Choudhry M, Schwacha M, Bland K, et al. Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway. J Leukoc Biol. 2007;82:774-80 pubmed
Choi G, Vlaar A, Schouten M, Van T Veer C, van der Poll T, Levi M, et al. Natural anticoagulants limit lipopolysaccharide-induced pulmonary coagulation but not inflammation. Eur Respir J. 2007;30:423-8 pubmed
Sheikh N, Dudas J, Ramadori G. Changes of gene expression of iron regulatory proteins during turpentine oil-induced acute-phase response in the rat. Lab Invest. 2007;87:713-25 pubmed
McCarter S, Mei S, Lai P, Zhang Q, Parker C, Suen R, et al. Cell-based angiopoietin-1 gene therapy for acute lung injury. Am J Respir Crit Care Med. 2007;175:1014-26 pubmed
Yang S, Hu S, Choudhry M, Rue L, Bland K, Chaudry I. Anti-rat soluble IL-6 receptor antibody down-regulates cardiac IL-6 and improves cardiac function following trauma-hemorrhage. J Mol Cell Cardiol. 2007;42:620-30 pubmed
Barkho B, Song H, Aimone J, Smrt R, Kuwabara T, Nakashima K, et al. Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation. Stem Cells Dev. 2006;15:407-21 pubmed
Holly M, Dear J, Hu X, Schechter A, Gladwin M, Hewitt S, et al. Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure. Kidney Int. 2006;70:496-506 pubmed
Satofuka S, Ichihara A, Nagai N, Yamashiro K, Koto T, Shinoda H, et al. Suppression of ocular inflammation in endotoxin-induced uveitis by inhibiting nonproteolytic activation of prorenin. Invest Ophthalmol Vis Sci. 2006;47:2686-92 pubmed
Yang S, Zou L, Bounelis P, Chaudry I, Chatham J, Marchase R. Glucosamine administration during resuscitation improves organ function after trauma hemorrhage. Shock. 2006;25:600-7 pubmed
Cao Z, Gao Y, Bryson J, Hou J, Chaudhry N, Siddiq M, et al. The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth. J Neurosci. 2006;26:5565-73 pubmed
Chen C, Wang S, Tsay S, Lee F, Lu R, Chang F, et al. Effects of gabexate mesilate on serum inflammatory cytokines in rats with acute necrotizing pancreatitis. Cytokine. 2006;33:95-9 pubmed
Hofstetter C, Flondor M, Hoegl S, Muhl H, Zwissler B. Interleukin-10 aerosol reduces proinflammatory mediators in bronchoalveolar fluid of endotoxemic rat. Crit Care Med. 2005;33:2317-22 pubmed
Robinson S, Petelenz K, Li Q, Cohen M, Dechant A, Tabrizi N, et al. Developmental changes induced by graded prenatal systemic hypoxic-ischemic insults in rats. Neurobiol Dis. 2005;18:568-81 pubmed
Holguin A, O Connor K, Biedenkapp J, Campisi J, Wieseler Frank J, Milligan E, et al. HIV-1 gp120 stimulates proinflammatory cytokine-mediated pain facilitation via activation of nitric oxide synthase-I (nNOS). Pain. 2004;110:517-30 pubmed
Klein D, Schubert T, Horch R, Jauch K, Jeschke M. Insulin treatment improves hepatic morphology and function through modulation of hepatic signals after severe trauma. Ann Surg. 2004;240:340-9 pubmed
Nishida T, Miyata S, Itoh Y, Mizuki N, Ohgami K, Shiratori K, et al. Anti-inflammatory effects of alpha-melanocyte-stimulating hormone against rat endotoxin-induced uveitis and the time course of inflammatory agents in aqueous humor. Int Immunopharmacol. 2004;4:1059-66 pubmed
Jeschke M, Klein D, Bolder U, Einspanier R. Insulin attenuates the systemic inflammatory response in endotoxemic rats. Endocrinology. 2004;145:4084-93 pubmed
O Connor K, Holguin A, Hansen M, Maier S, Watkins L. A method for measuring multiple cytokines from small samples. Brain Behav Immun. 2004;18:274-80 pubmed
Long J, Tong H, Shannon P, DeMaria T. Differential expression of cytokine genes and inducible nitric oxide synthase induced by opacity phenotype variants of Streptococcus pneumoniae during acute otitis media in the rat. Infect Immun. 2003;71:5531-40 pubmed
Castellanos M, Puig N, Carbonell T, Castillo J, Martinez J, Rama R, et al. Iron intake increases infarct volume after permanent middle cerebral artery occlusion in rats. Brain Res. 2002;952:1-6 pubmed
product information
brand :
R&D Systems
master code :
R6000B
SKU :
PR6000B
product name :
Rat IL-6 Quantikine ELISA Kit
description :
The Rat IL-6 Quantikine ELISA Kit from R&D Systems quantifies rat IL-6 in cell culture supernates (50 ul), serum (50 ul), edta plasma (50 ul).
target :
IL-6
category :
ELISAs
unit size :
1 Pack (50 Plates)
species :
Rat
specificity :
Natural and recombinant rat IL-6
gene symbol :
Il6
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Serum (50 uL), EDTA Plasma (50 uL)
elisaSensitivity :
36 pg/mL
elisaRange :
62.50 - 4000 pg/mL
applications :
ELISA
product details :
The Quantikine Rat IL-6 Immunoassay is a 4.5 hour solid phase ELISA designed to measure rat IL-6 in cell culture supernates, rat serum, and plasma. It contains E. coli -expressed recombinant rat IL-6 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant protein. Results obtained using natural rat IL-6 showed dose-response curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural rat IL-6.
alt name :
B-cell differentiation factor, B-cell stimulatory factor 2, BSF2, BSF-2, CDF, CTL differentiation factor, HSF, hybridoma growth factor, IFNB2, IFN-beta-2, IL6, IL-6, Interferon beta-2, interleukin 6 (interferon, beta 2), interleukin BSF-2, interleukin-6, MGI-2A
storage :
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.