product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human CAR/NR1I3 Antibody
catalog :
PP-N4111-00
quantity :
100 ug
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N4111
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 8
Reference
Bwayi M, García Maldonado E, Chai S, Xie B, Chodankar S, Huber A, et al. Molecular basis of crosstalk in nuclear receptors: heterodimerization between PXR and CAR and the implication in gene regulation. Nucleic Acids Res. 2022;50:3254-3275 pubmed publisher
Pan C, Kang J, Hwang J, Li J, Boese A, Wang X, et al. Cisplatin-mediated activation of glucocorticoid receptor induces platinum resistance via MAST1. Nat Commun. 2021;12:4960 pubmed publisher
Milkiewicz M, Klak M, Kempińska Podhorodecka A, Wiechowska Kozlowska A, Urasinska E, Blatkiewicz M, et al. Impaired Hepatic Adaptation to Chronic Cholestasis induced by Primary Sclerosing Cholangitis. Sci Rep. 2016;6:39573 pubmed publisher
Chen T, Laurenzana E, Coslo D, Chen F, Omiecinski C. Proteasomal interaction as a critical activity modulator of the human constitutive androstane receptor. Biochem J. 2014;458:95-107 pubmed publisher
Ou Z, Shi X, Gilroy R, Kirisci L, Romkes M, Lynch C, et al. Regulation of the human hydroxysteroid sulfotransferase (SULT2A1) by RORα and RORγ and its potential relevance to human liver diseases. Mol Endocrinol. 2013;27:106-15 pubmed publisher
Mebis L, Eerdekens A, Guiza F, Princen L, Derde S, Vanwijngaerden Y, et al. Contribution of nutritional deficit to the pathogenesis of the nonthyroidal illness syndrome in critical illness: a rabbit model study. Endocrinology. 2012;153:973-84 pubmed publisher
Sueyoshi T, Green W, Vinal K, Woodrum T, Moore R, Negishi M. Garlic extract diallyl sulfide (DAS) activates nuclear receptor CAR to induce the Sult1e1 gene in mouse liver. PLoS ONE. 2011;6:e21229 pubmed publisher
Surapureddi S, Rana R, Reddy J, Goldstein J. Nuclear receptor coactivator 6 mediates the synergistic activation of human cytochrome P-450 2C9 by the constitutive androstane receptor and hepatic nuclear factor-4alpha. Mol Pharmacol. 2008;74:913-23 pubmed publisher
product information
brand :
R&D Systems
master code :
PP-N4111-00
SKU :
PP-N4111-00
product name :
Human CAR/NR1I3 Antibody
unit size :
100 ug
seo description :
The Human CAR/NR1I3 Antibody from R&D Systems is a mouse monoclonal antibody to CAR/NR1I3. This antibody reacts with human,mouse,primate - chlorocebus aethiops (african green monkey),rabbit,transgenic mouse. The Human CAR/NR1I3 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry,Immunoprecipitation.
target :
CAR/NR1I3
category :
Primary Antibodies
buffer :
A liquid formulation in physiologic saline with 0.1% NaN3.
clonality :
Monoclonal
clone :
N4111
conjugate :
Unconjugated
dilution :
Western Blot, Immunohistochemistry, Immunoprecipitation
host :
Mouse
isotype :
IgG1
species :
Human,Mouse,Primate - Chlorocebus aethiops (African Green Monkey),Rabbit,Transgenic Mouse
gene symbol :
NR1I3
applications :
Immunoprecipitation,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry
USD :
469 USD
alt names :
CARCAR1, Constitutive activator of retinoid response, constitutive active receptor, Constitutive active response, Constitutive androstane receptor, MB67, MGC150433, MGC97144, MGC97209, NR1I3, nuclear receptor subfamily 1 group I member 3, nuclear receptor subfamily 1, group I, member 3, orphan nuclear hormone receptor, Orphan nuclear receptor MB67
storage :
Store the unopened product at -70 ░C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.