product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human LXR beta/NR1H2 Antibody (Clone K8917)
catalog :
PP-K8917-00
quantity :
100 ug
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
K8917
reactivity :
human
application :
western blot, ELISA, immunoprecipitation
more info or order :
R&D Systems product webpage
citations: 5
Reference
Premaratne A, Basu S, Bagchi A, Zhou T, Feng Q, Lin C. Liver X Receptor Ligand GAC0001E5 Downregulates Antioxidant Capacity and ERBB2/HER2 Expression in HER2-Positive Breast Cancer Cells. Cancers (Basel). 2024;16: pubmed publisher
Premaratne A, Ho C, Basu S, Khan A, Bawa Khalfe T, Lin C. Liver X Receptor Inverse Agonist GAC0001E5 Impedes Glutaminolysis and Disrupts Redox Homeostasis in Breast Cancer Cells. Biomolecules. 2023;13: pubmed publisher
Fan Q, Nørgaard R, Grytten I, Ness C, Lucas C, Vekterud K, et al. LXRα Regulates ChREBPα Transactivity in a Target Gene-Specific Manner through an Agonist-Modulated LBD-LID Interaction. Cells. 2020;9: pubmed publisher
Dong B, Kan C, Singh A, Liu J. High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway. J Lipid Res. 2013;54:1241-54 pubmed publisher
Wu M, Dong B, Cao A, Li H, Liu J. Delineation of molecular pathways that regulate hepatic PCSK9 and LDL receptor expression during fasting in normolipidemic hamsters. Atherosclerosis. 2012;224:401-10 pubmed publisher
product information
master code :
PP-K8917-00
SKU :
PP-K8917-00
product name :
Human LXR beta/NR1H2 Antibody (Clone K8917)
unit size :
100 ug
description :
The Human LXR beta/NR1H2 Antibody (Clone K8917) from R&D Systems is a mouse monoclonal antibody to LXR beta/NR1H2. This antibody reacts with hamster,human. The Human LXR beta/NR1H2 Antibody (Clone K8917) has been validated for the following applications: Western Blot,Immunoprecipitation,Direct ELISA.
target :
LXR beta/NR1H2
category :
Primary Antibodies
buffer :
A liquid formulation in physiologic saline with 0.1% NaN3.
clonality :
Monoclonal
clone :
K8917
conjugate :
Unconjugated
host :
Mouse
isotype :
IgG2a
species :
Hamster,Human
gene symbol :
NR1H2
applications :
Western Blot,Immunoprecipitation,Direct ELISA
USD :
479 USD
alt names :
Liver X receptor beta, LXR-b, NER-I, NERliver X receptor-beta, NR1H2, nuclear orphan receptor LXR-beta, Nuclear receptor NER, Nuclear receptor subfamily 1 group H member 2, nuclear receptor subfamily 1, group H, member 2, oxysterols receptor LXR-beta, RIP15, steroid hormone-nuclear receptor NER, Ubiquitously-expressed nuclear receptorLXRB, UNR, UNRLX receptor beta
storage :
Store the unopened product at -70 ░C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.