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company name :
R&D Systems
product type :
antibody
product name :
Human ERR gamma/NR3B3 Antibody
catalog :
PP-H6812-00
quantity :
100 ug
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H6812
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, chromatin immunoprecipitation
more info or order :
R&D Systems product webpage
citations: 15
Reference
Trevisan A, Han K, Chapman P, Kulkarni A, Hinton J, Ramirez C, et al. The transcriptomic landscape of spinal V1 interneurons reveals a role for En1 in specific elements of motor output. bioRxiv. 2024;: pubmed publisher
Jung Y, Radhakrishnan K, Hammad S, M xfc ller S, M xfc ller J, Noh J, et al. ERRγ-inducible FGF23 promotes alcoholic liver injury through enhancing CYP2E1 mediated hepatic oxidative stress. Redox Biol. 2024;71:103107 pubmed publisher
Jung Y, Radhakrishnan K, Kim H, Kim Y, Lee C, Choi H. Macrophage stimulating protein is a novel transcriptional target of estrogen related receptor gamma in alcohol-intoxicated mice. Cell Signal. 2024;116:111059 pubmed publisher
Singh T, Lee J, Son K, Lee B, Kim S, Gulwani D, et al. An Inverse Agonist of Estrogen-Related Receptor Gamma, GSK5182, Enhances Na+/I- Symporter Function in Radioiodine-Refractory Papillary Thyroid Cancer Cells. Cells. 2023;12: pubmed publisher
Na S, Kim K, Jung Y, Kim D, Kim J, Cho S, et al. An Inverse Agonist GSK5182 Increases Protein Stability of the Orphan Nuclear Receptor ERRγ via Inhibition of Ubiquitination. Int J Mol Sci. 2022;24: pubmed publisher
Khan M, Cherukuri P, Negro F, Rajput A, Fabrowski P, Bansal V, et al. ERR2 and ERR3 promote the development of gamma motor neuron functional properties required for proprioceptive movement control. PLoS Biol. 2022;20:e3001923 pubmed publisher
Soulard C, Salsac C, Mouzat K, Hilaire C, Roussel J, Mezghrani A, et al. Spinal Motoneuron TMEM16F Acts at C-boutons to Modulate Motor Resistance and Contributes to ALS Pathogenesis. Cell Rep. 2020;30:2581-2593.e7 pubmed publisher
Lunde A, Okaty B, Dymecki S, Glover J. Molecular Profiling Defines Evolutionarily Conserved Transcription Factor Signatures of Major Vestibulospinal Neuron Groups. Eneuro. 2019;6: pubmed publisher
Sweeney L, Bikoff J, Gabitto M, Brenner Morton S, Baek M, Yang J, et al. Origin and Segmental Diversity of Spinal Inhibitory Interneurons. Neuron. 2018;97:341-355.e3 pubmed publisher
Lee J, Kim E, Kim D, Lee J, Park S, Lee I, et al. Hypoxia induces PDK4 gene expression through induction of the orphan nuclear receptor ERR?. PLoS ONE. 2012;7:e46324 pubmed publisher
Kim D, Kim J, Koh M, Kim Y, Lee J, Chanda D, et al. Estrogen-related receptor ? (ERR?) is a novel transcriptional regulator of phosphatidic acid phosphatase, LIPIN1, and inhibits hepatic insulin signaling. J Biol Chem. 2011;286:38035-42 pubmed publisher
Berry R, Harewood L, Pei L, Fisher M, BROWNSTEIN D, Ross A, et al. Esrrg functions in early branch generation of the ureteric bud and is essential for normal development of the renal papilla. Hum Mol Genet. 2011;20:917-26 pubmed publisher
Xie Y, Park J, Kim D, Hwang J, Oh S, Park S, et al. Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. J Biol Chem. 2009;284:28762-74 pubmed publisher
Spector N, Yarden Y, Smith B, Lyass L, Trusk P, Pry K, et al. Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells. Proc Natl Acad Sci U S A. 2007;104:10607-12 pubmed
Yu S, Wang X, Ng C, Chen S, Chan F. ERRgamma suppresses cell proliferation and tumor growth of androgen-sensitive and androgen-insensitive prostate cancer cells and its implication as a therapeutic target for prostate cancer. Cancer Res. 2007;67:4904-14 pubmed
product information
master code :
PP-H6812-00
SKU :
PP-H6812-00
product name :
Human ERR gamma/NR3B3 Antibody
unit size :
100 ug
description :
The Human ERR gamma/NR3B3 Antibody from R&D Systems is a mouse monoclonal antibody to ERR gamma/NR3B3. This antibody reacts with human,mouse,transgenic mouse,xenopus. The Human ERR gamma/NR3B3 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunoprecipitation,Chromatin Immunoprecipitation (ChIP),Direct ELISA.
target :
ERR gamma/NR3B3
category :
Primary Antibodies
buffer :
A liquid formulation in physiologic saline with 0.1% NaN3.
clonality :
Monoclonal
clone :
H6812
conjugate :
Unconjugated
host :
Mouse
isotype :
IgG2a
species :
Human,Mouse,Transgenic Mouse,Xenopus
gene symbol :
ESRRG
applications :
Immunohistochemistry,Immunoprecipitation,Western Blot,Chromatin Immunoprecipitation (ChIP),Direct ELISA
USD :
479 USD
alt names :
DKFZp781L1617, ERR gamma-2, ERR3, ERRG2, ERRgamma, ESRRG, Estrogen receptor-related protein 3, estrogen-related receptor gamma, FLJ16023, KIAA0832, NR3B3, Nuclear receptor subfamily 3 group B member 3
storage :
Store the unopened product at -70 ░C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.