product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ERR beta/NR3B2 Antibody
catalog :
PP-H6705-00
quantity :
100 ug
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H6705
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
more info or order :
citations: 27
Reference
Li Q, Zheng P. ESRRB inhibits the TGF-β signaling pathway to drive cell proliferation in cervical cancer. Cancer Res. 2023;: pubmed publisher
Zhu Z, Chen X, Guo A, Manzano T, Walsh P, Wills K, et al. Mitotic bookmarking by SWI/SNF subunits. Nature. 2023;618:180-187 pubmed publisher
Yelagandula R, Stecher K, Novatchkova M, Michetti L, Michlits G, Wang J, et al. ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers. Nat Cell Biol. 2023;25:42-55 pubmed publisher
Khan M, Cherukuri P, Negro F, Rajput A, Fabrowski P, Bansal V, et al. ERR2 and ERR3 promote the development of gamma motor neuron functional properties required for proprioceptive movement control. PLoS Biol. 2022;20:e3001923 pubmed publisher
Herchcovici Levy S, Feldman Cohen S, Arnon L, Lahav S, Awawdy M, Alajem A, et al. Esrrb is a cell-cycle-dependent associated factor balancing pluripotency and XEN differentiation. Stem Cell Reports. 2022;17:1334-1350 pubmed publisher
Suzuki D, Okura K, Nagakura S, Ogawa H. CDX2 downregulation in mouse mural trophectoderm during peri-implantation is heteronomous, dependent on the YAP-TEAD pathway and controlled by estrogen-induced factors. Reprod Med Biol. 2022;21:e12446 pubmed publisher
Jin K, Zuo R, Anastassiadis K, Klungland A, Marr C, Filipczyk A. N6-methyladenosine (m6A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Bayerl J, Ayyash M, Shani T, Manor Y, Gafni O, Massarwa R, et al. Principles of signaling pathway modulation for enhancing human naive pluripotency induction. Cell Stem Cell. 2021;: pubmed publisher
Fan R, Kim Y, Wu J, Chen R, Zeuschner D, Mildner K, et al. Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause. Nat Commun. 2020;11:5499 pubmed publisher
Lasman L, Krupalnik V, Viukov S, Mor N, Aguilera Castrejon A, Schneir D, et al. Context-dependent functional compensation between Ythdf m6A reader proteins. Genes Dev. 2020;34:1373-1391 pubmed publisher
Huyghe A, Furlan G, Ozmadenci D, Galonska C, Charlton J, Gaume X, et al. Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling. Nat Cell Biol. 2020;22:389-400 pubmed publisher
Fernandez A, Geng X, Chaldekas K, Harris B, Duttargi A, Berry V, et al. The orphan nuclear receptor estrogen-related receptor beta (ERRβ) in triple-negative breast cancer. Breast Cancer Res Treat. 2020;179:585-604 pubmed publisher
Garland W, Comet I, Wu M, Radzisheuskaya A, Rib L, Vitting Seerup K, et al. A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2. Cell Rep. 2019;29:1800-1811.e6 pubmed publisher
Stuart H, Stirparo G, Lohoff T, Bates L, Kinoshita M, Lim C, et al. Distinct Molecular Trajectories Converge to Induce Naive Pluripotency. Cell Stem Cell. 2019;25:388-406.e8 pubmed publisher
Bahat A, Goldman A, Zaltsman Y, Khan D, Halperin C, Amzallag E, et al. MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells. Nat Commun. 2018;9:5132 pubmed publisher
Sardina J, Collombet S, Tian T, Gomez A, Di Stefano B, Berenguer C, et al. Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate. Cell Stem Cell. 2018;23:727-741.e9 pubmed publisher
Andersson Rolf A, Mustata R, Merenda A, Kim J, Perera S, Grego T, et al. One-step generation of conditional and reversible gene knockouts. Nat Methods. 2017;14:287-289 pubmed publisher
Yang Y, Jiang Z, Bolnick A, Dai J, Puscheck E, Rappolee D. Departure from optimal O2 level for mouse trophoblast stem cell proliferation and potency leads to most rapid AMPK activation. J Reprod Dev. 2017;63:87-94 pubmed publisher
Heckler M, Zeleke T, Divekar S, Fernandez A, Tiek D, Woodrick J, et al. Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer. Oncotarget. 2016;7:47201-47220 pubmed publisher
Lu Y, Li J, Cheng J, Lubahn D. Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells. BMC Mol Biol. 2015;16:21 pubmed publisher
Lu Y, Li J, Cheng J, Lubahn D. Genes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen related receptor β. BMC Mol Biol. 2015;16:19 pubmed publisher
Heckler M, Riggins R. ERRβ splice variants differentially regulate cell cycle progression. Cell Cycle. 2015;14:31-45 pubmed publisher
Kumar R, Cahan P, Shalek A, Satija R, DaleyKeyser A, Li H, et al. Deconstructing transcriptional heterogeneity in pluripotent stem cells. Nature. 2014;516:56-61 pubmed publisher
Leroy F, Lamotte D Incamps B, Imhoff Manuel R, Zytnicki D. Early intrinsic hyperexcitability does not contribute to motoneuron degeneration in amyotrophic lateral sclerosis. elife. 2014;3: pubmed publisher
Radzisheuskaya A, Chia G, Dos Santos R, Theunissen T, Castro L, Nichols J, et al. A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages. Nat Cell Biol. 2013;15:579-90 pubmed publisher
Percharde M, Lavial F, Ng J, Kumar V, Tomaz R, Martin N, et al. Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming. Genes Dev. 2012;26:2286-98 pubmed publisher
van den Berg D, Zhang W, Yates A, Engelen E, Takacs K, Bezstarosti K, et al. Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression. Mol Cell Biol. 2008;28:5986-95 pubmed publisher
product information
brand :
R&D Systems
master code :
PP-H6705-00
SKU :
PP-H6705-00
product name :
Human ERR beta/NR3B2 Antibody
unit size :
100 ug
seo description :
The Human ERR beta/NR3B2 Antibody from R&D Systems is a mouse monoclonal antibody to ERR beta/NR3B2. This antibody reacts with human,mouse. The Human ERR beta/NR3B2 Antibody has been validated for the following applications: Immunocytochemistry,Bioassay,Immunoprecipitation,Western Blot,Immunohistochemistry,Chromatin Immunoprecipitation (ChIP).
target :
ERR beta/NR3B2
category :
Primary Antibodies
buffer :
A liquid formulation in physiologic saline with 0.1% NaN3.
clonality :
Monoclonal
clone :
H6705
conjugate :
Unconjugated
dilution :
Western Blot, Immunohistochemistry 5-15 ug/mL, Immunoprecipitation
host :
Mouse
isotype :
IgG2a
species :
Human,Mouse
gene symbol :
ESRRB
top caption :
Detection of Mouse ERR beta/NR3B2 by Immunocytochemistry/Immunofluorescence
applications :
Bioassay,Immunohistochemistry,Immunoprecipitation,Western Blot,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry
USD :
479 USD
alt names :
ERR2, ESRL2, ESRRB, estrogen-related receptor beta, NR3B2
storage :
Store the unopened product at -70 ░C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.