product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human PPAR alpha /NR1C1 Antibody
catalog :
PP-H0723-00
quantity :
100 ug
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H0723
reactivity :
human, mouse
application :
western blot, ELISA, immunoprecipitation, chromatin immunoprecipitation
more info or order :
R&D Systems product webpage
citations: 5
Reference
Wang F, Cao C, Han K, Zhao Y, Cai M, Xiang Z, et al. APC-activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exosome production. J Clin Invest. 2019;129:727-743 pubmed publisher
Thomas M, Winter S, Klumpp B, Turpeinen M, Klein K, Schwab M, et al. Peroxisome proliferator-activated receptor alpha, PPARα, directly regulates transcription of cytochrome P450 CYP2C8. Front Pharmacol. 2015;6:261 pubmed publisher
Lien S, Wei S, Chang S, Chang M, Chang J, Chiu J. Activation of PPAR-? induces cell cycle arrest and inhibits transforming growth factor-?1 induction of smooth muscle cell phenotype in 10T1/2 mesenchymal cells. Cell Signal. 2013;25:1252-63 pubmed publisher
Zhou J, Wang K, Wu W, Subramaniam S, Shyy J, Chiu J, et al. MicroRNA-21 targets peroxisome proliferators-activated receptor-alpha in an autoregulatory loop to modulate flow-induced endothelial inflammation. Proc Natl Acad Sci U S A. 2011;108:10355-60 pubmed publisher
Huang W, Rha G, Han M, Eum S, Andras I, Zhong Y, et al. PPARalpha and PPARgamma effectively protect against HIV-induced inflammatory responses in brain endothelial cells. J Neurochem. 2008;107:497-509 pubmed publisher
product information
master code :
PP-H0723-00
SKU :
PP-H0723-00
product name :
Human PPAR alpha /NR1C1 Antibody
unit size :
100 ug
description :
The Human PPAR alpha /NR1C1 Antibody from R&D Systems is a mouse monoclonal antibody to PPAR alpha/NR1C1. This antibody reacts with human,mouse. The Human PPAR alpha /NR1C1 Antibody has been validated for the following applications: Chromatin Immunoprecipitation (ChIP),Western Blot,Immunoprecipitation,Direct ELISA,Gel Supershift Assay.
target :
PPAR alpha/NR1C1
category :
Primary Antibodies
buffer :
A liquid formulation in physiologic saline with 0.1% NaN3.
clonality :
Monoclonal
clone :
H0723
conjugate :
Unconjugated
host :
Mouse
immunogen :
Recombinant human PPAR alpha/NR1C1, aa 4-96
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
This antibody specifically recognizes human PPAR alpha and cross-reacts with mouse PPAR alpha . This antibody does not cross-react with human PPAR gamma or PPAR delta . Not yet tested in other species.
gene symbol :
PPARA
applications :
Western Blot,Chromatin Immunoprecipitation (ChIP),Immunoprecipitation,Direct ELISA,Gel Supershift Assay
USD :
479 USD
alt names :
alpha, hPPAR, NR1C1, NR1C1MGC2237, Nuclear receptor subfamily 1 group C member 1, peroxisome proliferator-activated receptor alpha, PPARA, PPARalpha, PPAR-alpha, PPARMGC2452
storage :
This antibody is stable for greater than six months when held at -20 ░C in a manual defrost freezer or at -70 ░C. Upon thawing, the antibody can be stored at 2-8 ░C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.