product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TR4/NR2C2 Antibody
catalog :
PP-H0107B-00
quantity :
100 ug
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H0107B
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1d
Xu M, Qin J, Wang L, Lee H, Kao C, Liu D, et al. Nuclear receptors regulate alternative lengthening of telomeres through a novel noncanonical FANCD2 pathway. Sci Adv. 2019;5:eaax6366 pubmed publisher
  • immunohistochemistry - paraffin section; human
  • western blot; human
Ding X, Yang D, Lee S, Chen Y, Xia L, Lin S, et al. TR4 nuclear receptor promotes prostate cancer metastasis via upregulation of CCL2/CCR2 signaling. Int J Cancer. 2015;136:955-64 pubmed publisher
Barroso Gonz xe1 lez J, Garc xed a Exp xf3 sito L, Galaviz P, Lynskey M, Allen J, Hoang S, et al. Anti-recombination function of MutSα restricts telomere extension by ALT-associated homology-directed repair. Cell Rep. 2021;37:110088 pubmed publisher
Porreca R, Herrera Moyano E, Skourti E, Law P, Gonzalez Franco R, Montoya A, et al. TRF1 averts chromatin remodelling, recombination and replication dependent-break induced replication at mouse telomeres. elife. 2020;9: pubmed publisher
Ding X, Yang D, Xia L, Chen B, Yu S, Niu Y, et al. Targeting TR4 nuclear receptor suppresses prostate cancer invasion via reduction of infiltrating macrophages with alteration of the TIMP-1/MMP2/MMP9 signals. Mol Cancer. 2015;14:16 pubmed publisher
product information
master code :
PP-H0107B-00
SKU :
PP-H0107B-00
product name :
Human TR4/NR2C2 Antibody
unit size :
100 ug
description :
The Human TR4/NR2C2 Antibody from R&D Systems is a mouse monoclonal antibody to TR4/NR2C2. This antibody reacts with human. The Human TR4/NR2C2 Antibody has been validated for the following applications: Immunohistochemistry-Paraffin,Immunohistochemistry,Immunoprecipitation,Western Blot,Direct ELISA.
target :
TR4/NR2C2
category :
Primary Antibodies
buffer :
A liquid formulation in physiologic saline with 0.1% NaN3.
clonality :
Monoclonal
clone :
H0107B
conjugate :
Unconjugated
host :
Mouse
immunogen :
Recombinant human TR4/NR2C2
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
This antibody specifically recognizes human TR4 and cross-reacts with mouse and rat TR4. Not yet tested in other species.
gene symbol :
NR2C2
Antibody validation :
Knockout/Knockdown
top caption :
Detection of Human TR4/NR2C2 by Immunocytochemistry/Immunofluorescence
applications :
Immunohistochemistry-Paraffin,Immunohistochemistry,Immunoprecipitation,Western Blot,Direct ELISA
USD :
469 USD
alt names :
hTAK1, NR2C2, Nuclear hormone receptor TR4, nuclear receptor subfamily 2 group C member 2, nuclear receptor subfamily 2, group C, member 2, Orphan nuclear receptor TAK1, Orphan nuclear receptor TR4, TAK1, TAK1TR4TR2R1, Testicular receptor 4, TR4 nuclear hormone receptor
storage :
This antibody is stable for greater than six months when held at -20 ░C in a manual defrost freezer or at -70 ░C. Upon thawing, the antibody can be stored at 2-8 ░C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.