product summary
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company name :
R&D Systems
product type :
antibody
product name :
Neuron-specific ▀-III Tubulin NorthernLightsÖ NL557-conjugated Antibody
catalog :
NL1195R
quantity :
0.5 mL
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
TuJ-1
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 12
Reference
Surico P, Narimatsu A, Forouzanfar K, Singh R, Shoushtari S, Dana R, et al. Effects of Diabetes Mellitus on Corneal Immune Cell Activation and the Development of Keratopathy. Cells. 2024;13: pubmed publisher
Yuan K, Zheng J, Shen X, Wu Y, Han Y, Jin X, et al. Sensory nerves promote corneal inflammation resolution via CGRP mediated transformation of macrophages to the M2 phenotype through the PI3K/AKT signaling pathway. Int Immunopharmacol. 2022;102:108426 pubmed publisher
Okada Y, Zhang Y, Zhang L, Yeh L, Wang Y, Saika S, et al. Shp2-mediated MAPK pathway regulates ΔNp63 in epithelium to promote corneal innervation and homeostasis. Lab Invest. 2019;: pubmed publisher
Wu M, Liu J, Li F, Huang S, He J, Xue Y, et al. Antibiotic-induced dysbiosis of gut microbiota impairs corneal development in postnatal mice by affecting CCR2 negative macrophage distribution. Mucosal Immunol. 2020;13:47-63 pubmed publisher
Ahlfors J, Azimi A, El Ayoubi R, Velumian A, Vonderwalde I, Boscher C, et al. Examining the fundamental biology of a novel population of directly reprogrammed human neural precursor cells. Stem Cell Res Ther. 2019;10:166 pubmed publisher
LEE P, Gao N, Dike M, Shkilnyy O, Me R, Zhang Y, et al. Opposing Effects of Neuropilin-1 and -2 on Sensory Nerve Regeneration in Wounded Corneas: Role of Sema3C in Ameliorating Diabetic Neurotrophic Keratopathy. Diabetes. 2019;68:807-818 pubmed publisher
Liu J, Wu M, He J, Xiao C, Xue Y, Fu T, et al. Antibiotic-Induced Dysbiosis of Gut Microbiota Impairs Corneal Nerve Regeneration by Affecting CCR2-Negative Macrophage Distribution. Am J Pathol. 2018;188:2786-2799 pubmed publisher
Harris D, Yamaguchi T, Hamrah P. A Novel Murine Model of Radiation Keratopathy. Invest Ophthalmol Vis Sci. 2018;59:3889-3896 pubmed publisher
Paschalis E, Lei F, Zhou C, Kapoulea V, Thanos A, Dana R, et al. The Role of Microglia and Peripheral Monocytes in Retinal Damage after Corneal Chemical Injury. Am J Pathol. 2018;188:1580-1596 pubmed publisher
Wang H, Xiao C, Dong D, Lin C, Xue Y, Liu J, et al. Epothilone B Speeds Corneal Nerve Regrowth and Functional Recovery through Microtubule Stabilization and Increased Nerve Beading. Sci Rep. 2018;8:2647 pubmed publisher
Paschalis E, Zhou C, Lei F, Scott N, Kapoulea V, Robert M, et al. Mechanisms of Retinal Damage after Ocular Alkali Burns. Am J Pathol. 2017;187:1327-1342 pubmed publisher
Guo C, Li M, Qi X, Lin G, Cui F, Li F, et al. Intranasal delivery of nanomicelle curcumin promotes corneal epithelial wound healing in streptozotocin-induced diabetic mice. Sci Rep. 2016;6:29753 pubmed publisher
product information
master code :
NL1195R
SKU :
NL1195R
product name :
Neuron-specific ▀-III Tubulin NorthernLightsÖ NL557-conjugated Antibody
unit size :
0.5 mL
description :
The Neuron-specific ß-III Tubulin NorthernLights™ NL557-conjugated Antibody from R&D Systems is a mouse monoclonal antibody to beta-III Tubulin. This antibody reacts with human,mouse,multi-species,rabbit,transgenic mouse. The Neuron-specific ß-III Tubulin NorthernLights™ NL557-conjugated Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
beta-III Tubulin
category :
Primary Antibodies
buffer :
Supplied as a 10X solution of antibody in PBS containing sodium azide.
clonality :
Monoclonal
clone :
TuJ-1
conjugate :
NL557
host :
Mouse
immunogen :
Rat brain-derived microtubules
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Multi-Species,Rabbit,Transgenic Mouse
specificity :
Detects mammalian and chicken neuron-specific ▀-III tubulin but not other ▀-tubulin isotypes in Western blots.
gene symbol :
TUBB3
top caption :
ss-III Tubulin antibody in Rat Cortical Stem Cells by Immunocytochemistry (ICC).
applications :
Immunohistochemistry,Flow Cytometry,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
439 USD
alt names :
Beta3-tubulin, beta-4, betaIII Tubulin, beta-Tubulin III, Class III beta-tubulin, TUBB3, TUBB4 CFEOM3A, Tubulin Beta 3, tubulin beta-3 chain, Tubulin beta-4, Tubulin beta-4 chain, Tubulin beta-III, tubulin, beta 3, TUJ1 antigen, TUJ-1 antigen
storage :
Protect from light. 12 months from date of receipt, 2 to 8 ░C as supplied.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.