Mouse VEGFR1/Flt-1 Quantikine ELISA Kit | R&D Systems MVR100 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Mouse VEGFR1/Flt-1 Quantikine ELISA Kit

catalog :

MVR100

quantity :

1 Kit

price :

655 USD

citations: 38

Reference
Alhasan M, Landa M, Garc xed a S, Gerlach R, Harb H, Fahlbusch F, et al. Distinct gut microbial signature and altered short chain fatty acid metabolism at disease onset in a rat preclinical model of superimposed preeclampsia. Sci Rep. 2024;14:32137 pubmed publisher
Yang Z, Jia X, Deng Q, Luo M, Hou Y, Yue J, et al. Human umbilical cord mesenchymal stem cell-derived extracellular vesicles loaded with TFCP2 activate Wnt/β-catenin signaling to alleviate preeclampsia. Int Immunopharmacol. 2023;115:109732 pubmed publisher
Liu X, Li Z, Sun J, Zhang Z, Li W. Interaction between PD-L1 and soluble VEGFR1 in glioblastoma-educated macrophages. BMC Cancer. 2023;23:259 pubmed publisher
Lu S, Omori H, Zhou Y, Lin Y, Liu C, Wu J, et al. VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes. MBio. 2022;13:e0123322 pubmed publisher
Jones Muhammad M, Shao Q, Cain Shields L, Shaffery J, Warrington J. Acid Sensing Ion Channel 2a Is Reduced in the Reduced Uterine Perfusion Pressure Mouse Model and Increases Seizure Susceptibility in Pregnant Mice. Cells. 2021;10: pubmed publisher
Shin Y, An S, Jeong J, Yang S, Lee G, Hong E, et al. Comparison of steroid hormones in three different preeclamptic models. Mol Med Rep. 2021;23: pubmed publisher
Parchem J, Kanasaki K, Lee S, Kanasaki M, Yang J, Xu Y, et al. STOX1 deficiency is associated with renin-mediated gestational hypertension and placental defects. JCI Insight. 2021;6: pubmed publisher
Dijkstra D, Verkaik Schakel R, Eskandar S, Limonciel A, Stojanovska V, Scherjon S, et al. Mid-gestation low-dose LPS administration results in female-specific excessive weight gain upon a western style diet in mouse offspring. Sci Rep. 2020;10:19618 pubmed publisher
Erlandsson L, Ducat A, Castille J, Zia I, Kalapotharakos G, Hedstrom E, et al. Alpha-1 microglobulin as a potential therapeutic candidate for treatment of hypertension and oxidative stress in the STOX1 preeclampsia mouse model. Sci Rep. 2019;9:8561 pubmed publisher
Cunningham M, Castillo J, Ibrahim T, Cornelius D, Campbell N, Amaral L, et al. AT1-AA (Angiotensin II Type 1 Receptor Agonistic Autoantibody) Blockade Prevents Preeclamptic Symptoms in Placental Ischemic Rats. Hypertension. 2018;71:886-893 pubmed publisher
Beharry K, Cai C, Ahmad T, Guzel S, Valencia G, Aranda J. Impact of Chronic Neonatal Intermittent Hypoxia on Severity of Retinal Damage in a Rat Model of Oxygen-Induced Retinopathy. J Nat Sci. 2018;4: pubmed
Reijnders D, Liu C, Xu X, Zhao A, Olson K, Butler S, et al. Celecoxib restores angiogenic factor expression at the maternal-fetal interface in the BPH/5 mouse model of preeclampsia. Physiol Genomics. 2018;50:385-392 pubmed publisher
Blois S, Freitag N, Tirado Gonzalez I, Cheng S, Heimesaat M, Bereswill S, et al. NK cell-derived IL-10 is critical for DC-NK cell dialogue at the maternal-fetal interface. Sci Rep. 2017;7:2189 pubmed publisher
Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti H, et al. Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun. 2017;8:14583 pubmed publisher
Erpenbeck L, Chowdhury C, Zsengellér Z, Gallant M, Burke S, Cifuni S, et al. PAD4 Deficiency Decreases Inflammation and Susceptibility to Pregnancy Loss in a Mouse Model. Biol Reprod. 2016;95:132 pubmed publisher
Denney J, Bird C, Gendron Fitzpatrick A, Sampene E, Bird I, Shah D. Renin-angiotensin system transgenic mouse model recapitulates pathophysiology similar to human preeclampsia with renal injury that may be mediated through VEGF. Am J Physiol Renal Physiol. 2017;312:F445-F455 pubmed publisher
Fushima T, Sekimoto A, Minato T, Ito T, Oe Y, Kisu K, et al. Reduced Uterine Perfusion Pressure (RUPP) Model of Preeclampsia in Mice. PLoS ONE. 2016;11:e0155426 pubmed publisher
Venditti C, Casselman R, Young I, Karumanchi S, Smith G. Carbon monoxide prevents hypertension and proteinuria in an adenovirus sFlt-1 preeclampsia-like mouse model. PLoS ONE. 2014;9:e106502 pubmed publisher
Ayala de la Peña F, Kanasaki K, Kanasaki M, Vong S, Rovira C, Kalluri R. Specific activation of K-RasG12D allele in the bladder urothelium results in lung alveolar and vascular defects. PLoS ONE. 2014;9:e95888 pubmed publisher
Luo Y, Kumar P, Chen C, Latham J, Wang L, Tudela C, et al. Estrogen-related receptor ? serves a role in blood pressure homeostasis during pregnancy. Mol Endocrinol. 2014;28:965-75 pubmed publisher
Craici I, Wagner S, Weissgerber T, Grande J, Garovic V. Advances in the pathophysiology of pre-eclampsia and related podocyte injury. Kidney Int. 2014;86:275-85 pubmed publisher
Justiniano S, Elavazhagan S, Fatehchand K, Shah P, Mehta P, Roda J, et al. Fc? receptor-induced soluble vascular endothelial growth factor receptor-1 (VEGFR-1) production inhibits angiogenesis and enhances efficacy of anti-tumor antibodies. J Biol Chem. 2013;288:26800-9 pubmed publisher
Suryawanshi A, Mulik S, Sharma S, Reddy P, Sehrawat S, Rouse B. Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor. J Immunol. 2011;186:3653-65 pubmed publisher
Kalkunte S, Boij R, Norris W, Friedman J, Lai Z, Kurtis J, et al. Sera from preeclampsia patients elicit symptoms of human disease in mice and provide a basis for an in vitro predictive assay. Am J Pathol. 2010;177:2387-98 pubmed publisher
Tam Tam K, LaMarca B, Arany M, Cockrell K, Fournier L, Murphy S, et al. Role of reactive oxygen species during hypertension in response to chronic antiangiogenic factor (sFlt-1) excess in pregnant rats. Am J Hypertens. 2011;24:110-3 pubmed publisher
Mazzone M, Dettori D, de Oliveira R, Loges S, Schmidt T, Jonckx B, et al. Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization. Cell. 2009;136:839-851 pubmed publisher
Satofuka S, Ichihara A, Nagai N, Noda K, Ozawa Y, Fukamizu A, et al. (Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system. Am J Pathol. 2008;173:1911-8 pubmed publisher
Poesen K, Lambrechts D, Van Damme P, Dhondt J, Bender F, Frank N, et al. Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration. J Neurosci. 2008;28:10451-9 pubmed publisher
Zhou C, Zhang Y, Irani R, Zhang H, Mi T, Popek E, et al. Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice. Nat Med. 2008;14:855-62 pubmed publisher
Izumi Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, et al. Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin. Invest Ophthalmol Vis Sci. 2008;49:1679-85 pubmed publisher
Xie B, Shen J, Dong A, Swaim M, Hackett S, Wyder L, et al. An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization. FASEB J. 2008;22:2775-83 pubmed publisher
Tsao P, Chan F, Wei S, Hsieh W, Chou H, Su Y, et al. Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis. Crit Care Med. 2007;35:1955-60 pubmed
Shimojo N, Jesmin S, Zaedi S, Otsuki T, Maeda S, Yamaguchi N, et al. Contributory role of VEGF overexpression in endothelin-1-induced cardiomyocyte hypertrophy. Am J Physiol Heart Circ Physiol. 2007;293:H474-81 pubmed
Hara A, Wada T, Furuichi K, Sakai N, Kawachi H, Shimizu F, et al. Blockade of VEGF accelerates proteinuria, via decrease in nephrin expression in rat crescentic glomerulonephritis. Kidney Int. 2006;69:1986-95 pubmed
Iemitsu M, Maeda S, Jesmin S, Otsuki T, Miyauchi T. Exercise training improves aging-induced downregulation of VEGF angiogenic signaling cascade in hearts. Am J Physiol Heart Circ Physiol. 2006;291:H1290-8 pubmed
Nagai N, Noda K, Urano T, Kubota Y, Shinoda H, Koto T, et al. Selective suppression of pathologic, but not physiologic, retinal neovascularization by blocking the angiotensin II type 1 receptor. Invest Ophthalmol Vis Sci. 2005;46:1078-84 pubmed
Sako A, Kitayama J, Koyama H, Ueno H, Uchida H, Hamada H, et al. Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer. Cancer Res. 2004;64:3624-8 pubmed
Maynard S, Min J, Merchan J, Lim K, Li J, Mondal S, et al. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest. 2003;111:649-58 pubmed

product information

master code :

MVR100

SKU :

MVR100

product name :

Mouse VEGFR1/Flt-1 Quantikine ELISA Kit

unit size :

1 Kit

description :

The Mouse VEGFR1/Flt-1 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies mouse VEGFR1/Flt-1 in cell culture supernates (50 ul), serum (25 ul), edta plasma (25 ul).

target :

VEGFR1/Flt-1

category :

ELISAs

species :

Mouse

specificity :

Natural and recombinant mouse sVEGF R1

gene symbol :

Flt1

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Serum (25 uL), EDTA Plasma (25 uL)

elisaSensitivity :

15.2 pg/mL

elisaRange :

125.00 - 8000 pg/mL

top caption :

Mouse VEGF R1/Flt-1 ELISA Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Mouse soluble VEGF R1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse sVEGF R1 in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant mouse VEGF R1 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural mouse sVEGF R1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring mouse sVEGF R1.

alt names :

EC 2.7.10, EC 2.7.10.1, FLT, FLT1, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.