Mouse IL-12 p40 NonAllele-specific Quantikine ELISA | R&D Systems MP400 product information

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product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Mouse IL-12 p40 NonAllele-specific Quantikine ELISA

catalog :

MP400

quantity :

1 Kit (2 Plates) (also 1 Pack (50 Plates), 1 Pack (6 Plates))

price :

835 USD

citations: 17

Reference
Hagan N, Kane J, Grover D, Woodworth L, Madore C, Saleh J, et al. CSF1R signaling is a regulator of pathogenesis in progressive MS. Cell Death Dis. 2020;11:904 pubmed publisher
Ylostalo J, Bartosh T, Coble K, Prockop D. Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype. Stem Cells. 2012;30:2283-96 pubmed publisher
Gais P, Reim D, Jusek G, Rossmann Bloeck T, Weighardt H, Pfeffer K, et al. Cutting edge: Divergent cell-specific functions of MyD88 for inflammatory responses and organ injury in septic peritonitis. J Immunol. 2012;188:5833-7 pubmed publisher
Gottfries J, Melgar S, Michaëlsson E. Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease. PLoS ONE. 2012;7:e30005 pubmed publisher
Bondue B, Vosters O, de Nadai P, Glineur S, De Henau O, Luangsay S, et al. ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia. PLoS Pathog. 2011;7:e1002358 pubmed publisher
Li N, Ghia J, Wang H, McClemens J, Cote F, Suehiro Y, et al. Serotonin activates dendritic cell function in the context of gut inflammation. Am J Pathol. 2011;178:662-71 pubmed publisher
Fukui R, Saitoh S, Matsumoto F, Kozuka Hata H, Oyama M, Tabeta K, et al. Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing. J Exp Med. 2009;206:1339-50 pubmed publisher
Liu Q, Cheng L, Yi L, Zhu N, Wood A, Changpriroa C, et al. p47phox deficiency induces macrophage dysfunction resulting in progressive crystalline macrophage pneumonia. Am J Pathol. 2009;174:153-63 pubmed publisher
Divangahi M, Mostowy S, Coulombe F, Kozak R, Guillot L, Veyrier F, et al. NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity. J Immunol. 2008;181:7157-65 pubmed
Li Q, Guo Z, Xu X, Xia S, Cao X. Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation. Eur J Immunol. 2008;38:2751-61 pubmed publisher
Kang M, Lee C, Lee J, Dela Cruz C, Chen Z, Enelow R, et al. Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice. J Clin Invest. 2008;118:2771-84 pubmed publisher
Yamazaki T, Nagata K, Kobayashi Y. Cytokine production by M-CSF- and GM-CSF-induced mouse bone marrow-derived macrophages upon coculturing with late apoptotic cells. Cell Immunol. 2008;251:124-30 pubmed publisher
Vanhoutte F, Paget C, Breuilh L, Fontaine J, Vendeville C, Goriely S, et al. Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells. Immunol Lett. 2008;116:86-94 pubmed publisher
Takahashi N, Kitazawa H, Iwabuchi N, Xiao J, Miyaji K, Iwatsuki K, et al. Oral administration of an immunostimulatory DNA sequence from Bifidobacterium longum improves Th1/Th2 balance in a murine model. Biosci Biotechnol Biochem. 2006;70:2013-7 pubmed
Burch L, Yang I, Whitehead G, Chao F, Berman K, Schwartz D. The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment. Am J Physiol Lung Cell Mol Physiol. 2006;291:L677-82 pubmed
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product information

master code :

MP400

SKU :

MP400

product name :

Mouse IL-12 p40 NonAllele-specific Quantikine ELISA

unit size :

1 Kit (2 Plates) (also 1 Pack (50 Plates), 1 Pack (6 Plates))

description :

The Mouse IL-12 p40 NonAllele-specific Quantikine ELISA from R&D Systems is a Solid Phase Sandwich ELISA that quantifies mouse IL-12/IL-23 p40 in cell culture supernates (50 ul), serum (25 ul), edta plasma (25 ul), heparin plasma (25 ul).

target :

IL-12/IL-23 p40

category :

ELISAs

species :

Mouse

specificity :

Natural and recombinant mouse IL-12/IL-23 p40

gene symbol :

Il12b

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Serum (25 uL), EDTA Plasma (25 uL), Heparin Plasma (25 uL)

elisaSensitivity :

2.7 pg/mL

elisaRange :

11.70 - 750 pg/mL

top caption :

Mouse IL-12/IL-23 p40 Non Allele-specific ELISA Standard Curve

applications :

ELISA

USD :

835 USD

product details :

The Quantikine Mouse IL-12/IL-23 p40 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse p40 subunit in IL-12 p70, IL-23, p40 homodimer, and p40 monomer in cell culture supernates, mouse serum, and plasma. It contains recombinant mouse IL-12/23 p40 homodimer and antibodies raised against the p40 subunit of recombinant mouse IL-12 p70. This immunoassay has been shown to accurately quantitate the recombinant mouse IL-12/IL-23 p40. Results obtained using natural mouse IL-12/IL-23 p40 showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-12/IL-23 p40.

alt names :

CLMF, CLMF p40, CLMF2, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL12 p40, IL-12 subunit p40, IL12B, IL-12B, IL-12BNK cell stimulatory factor chain 2, interleukin 12, p40, interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocytematuration factor 2, p40), interleukin-12 beta chain, interleukin-12 subunit beta, natural killer cell stimulatory factor, 40 kD subunit, NKSF, NKSF2, NKSF2IL12, subunit p40

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.