Mouse IGFBP-3 Quantikine ELISA Kit | R&D Systems MGB300 product information

product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Mouse IGFBP-3 Quantikine ELISA Kit

catalog :

MGB300

quantity :

1 Kit

price :

655 USD

more info or order :

R&D Systems product webpage

citations: 12

Reference
D Addio F, Maestroni A, Assi E, Ben Nasr M, Amabile G, Usuelli V, et al. The IGFBP3/TMEM219 pathway regulates beta cell homeostasis. Nat Commun. 2022;13:684 pubmed publisher
Sia K, Gan S, Mohd Rodhi S, Fu Z, Kopchick J, Waters M, et al. First use of gene therapy to treat growth hormone resistant dwarfism in a mouse model. Gene Ther. 2022;29:346-356 pubmed publisher
Thiebaut A, Buendia I, Ginet V, Lemarchand E, Boudjadja M, Hommet Y, et al. Thrombolysis by PLAT/tPA increases serum free IGF1 leading to a decrease of deleterious autophagy following brain ischemia. Autophagy. 2021;:1-21 pubmed publisher
Seo J, Kang M, Yang W, Hwang W, Kim S, Hong S, et al. Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity. Nat Commun. 2020;11:2024 pubmed publisher
Lu J, Lu L, Yu Y, Cluette Brown J, Martin C, Claud E. Effects of Intestinal Microbiota on Brain Development in Humanized Gnotobiotic Mice. Sci Rep. 2018;8:5443 pubmed publisher
Linder M, Hecking M, Glitzner E, Zwerina K, Holcmann M, Bakiri L, et al. EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation. Cell Death Differ. 2018;25:1094-1106 pubmed publisher
Nguyen K, Yao X, Erickson A, Mishra S, Nyomba B. Glucose intolerance in aging male IGFBP-3 transgenic mice: differential effects of human IGFBP-3 and its mutant IGFBP-3 devoid of IGF binding ability. Endocrinology. 2015;156:462-74 pubmed publisher
Eren M, Boe A, Murphy S, Place A, Nagpal V, Morales Nebreda L, et al. PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice. Proc Natl Acad Sci U S A. 2014;111:7090-5 pubmed publisher
Lloyd J, Masko E, Wu C, Keenan M, Pilla D, Aronson W, et al. Fish oil slows prostate cancer xenograft growth relative to other dietary fats and is associated with decreased mitochondrial and insulin pathway gene expression. Prostate Cancer Prostatic Dis. 2013;16:285-91 pubmed publisher
Pierroz D, Bonnet N, Bianchi E, Bouxsein M, Baldock P, Rizzoli R, et al. Deletion of ?-adrenergic receptor 1, 2, or both leads to different bone phenotypes and response to mechanical stimulation. J Bone Miner Res. 2012;27:1252-62 pubmed publisher
De Lorenzo M, Baljinnyam E, Vatner D, ABARZUA P, Vatner S, Rabson A. Caloric restriction reduces growth of mammary tumors and metastases. Carcinogenesis. 2011;32:1381-7 pubmed publisher
Callewaert F, Venken K, Kopchick J, Torcasio A, Van Lenthe G, Boonen S, et al. Sexual dimorphism in cortical bone size and strength but not density is determined by independent and time-specific actions of sex steroids and IGF-1: evidence from pubertal mouse models. J Bone Miner Res. 2010;25:617-26 pubmed publisher

image

image 1 :

Mouse IGFBP-3 ELISA Standard Curve

product information

master code :

MGB300

SKU :

MGB300

product name :

Mouse IGFBP-3 Quantikine ELISA Kit

unit size :

1 Kit

description :

The Mouse IGFBP-3 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies mouse IGFBP-3 in cell culture supernates (50 ul), edta plasma (10 ul).

target :

IGFBP-3

category :

ELISAs

species :

Mouse

specificity :

Natural and recombinant mouse IGFBP-3. This kit detects full-length and fragmented mouse IGFBP-3. It also detects IGF-I, IGF-II, IGF-I/ALS, and IGF-II/ALS complexed IGFBP-3.

gene symbol :

Igfbp3

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), EDTA Plasma (10 uL)

elisaSensitivity :

16 pg/mL

elisaRange :

78.10 - 5000 pg/mL

top caption :

Mouse IGFBP-3 ELISA Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Mouse IGFBP-3 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse IGFBP-3 in cell culture supernates and plasma. It contains NS0-expressed recombinant mouse IGFBP-3 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural mouse IGFBP-3 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring mouse IGFBP-3.

alt names :

acid stable subunit of the 140 K IGF complex, binding protein 29, binding protein 53, growth hormone-dependent binding protein, IBP-3, IBP3BP-53, IGF-binding protein 3, IGFBP3, IGFBP-3, insulin-like growth factor binding protein 3, insulin-like growth factor-binding protein 3

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.

more info or order :

R&D Systems product webpage