product summary
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company name :
R&D Systems
product type :
ELISA/assay
product name :
Mouse MFG-E8 Quantikine ELISA Kit
catalog :
MFGE80
quantity :
1 Kit
price :
655 USD
more info or order :
citations: 9
Reference
Sokolova D, Ghansah S, Puletti F, Georgiades T, De Schepper S, Zheng Y, et al. Astrocyte-derived MFG-E8 facilitates microglial synapse elimination in Alzheimer's disease mouse models. bioRxiv. 2024;: pubmed publisher
Chaung W, Zhang F, Ma G, Yen H, Jacob A, Brenner M, et al. Development of human cell-expressed tag-free rhMFG-E8 as a radiation mitigator and a therapeutic for acute kidney injury. Res Sq. 2023;: pubmed publisher
Han D, Lu D, Huang S, Pang J, Wu Y, Hu J, et al. Small extracellular vesicles from Ptpn1-deficient macrophages alleviate intestinal inflammation by reprogramming macrophage polarization via lactadherin enrichment. Redox Biol. 2022;58:102558 pubmed publisher
Ikemoto Uezumi M, Zhou H, Kurosawa T, Yoshimoto Y, Toyoda M, Kanazawa N, et al. Increased MFG-E8 at neuromuscular junctions is an exacerbating factor for sarcopenia-associated denervation. Aging Cell. 2022;21:e13536 pubmed publisher
Lu Y, Liu L, Pan J, Luo B, Zeng H, Shao Y, et al. MFG-E8 regulated by miR-99b-5p protects against osteoarthritis by targeting chondrocyte senescence and macrophage reprogramming via the NF-κB pathway. Cell Death Dis. 2021;12:533 pubmed publisher
Bu H, Subramanian S, Geng H, Wang X, Liu F, Chou P, et al. MFG-E8 Plays an Important Role in Attenuating Cerulein-Induced Acute Pancreatitis in Mice. Cells. 2021;10: pubmed publisher
Brelstaff J, Tolkovsky A, Ghetti B, Goedert M, Spillantini M. Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia. Cell Rep. 2018;24:1939-1948.e4 pubmed publisher
Uchiyama A, Yamada K, Ogino S, Yokoyama Y, Takeuchi Y, Udey M, et al. MFG-E8 regulates angiogenesis in cutaneous wound healing. Am J Pathol. 2014;184:1981-90 pubmed publisher
Li E, Noda M, Doi Y, Parajuli B, Kawanokuchi J, Sonobe Y, et al. The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid ? toxicity. J Neuroinflammation. 2012;9:148 pubmed publisher
image
image 1 :
R&D Systems MFGE80 image 1
Mouse MFG-E8 ELISA Standard Curve
product information
master code :
MFGE80
SKU :
MFGE80
product name :
Mouse MFG-E8 Quantikine ELISA Kit
unit size :
1 Kit
description :
The Mouse MFG-E8 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies mouse MFG-E8 in cell culture supernates (25 ul), serum (10 ul), heparin plasma (10 ul).
target :
MFG-E8
category :
ELISAs
species :
Mouse
specificity :
Natural and recombinant mouse MFG-E8
gene symbol :
Mfge8
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (25 uL), Serum (10 uL), Heparin Plasma (10 uL)
elisaSensitivity :
0.02 ng/mL
elisaRange :
0.13 - 8 ng/mL
top caption :
Mouse MFG-E8 ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Mouse MFG-E8 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse MFG-E8 in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant mouse MFG-E8 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant factor accurately. Results obtained using natural mouse MFG-E8 showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse MFG-E8.
alt names :
BA46, Breast epithelial antigen BA46, EDIL1, hP47, HsT19888, lactadherin, Lactahedrin, Medin, MFG1, MFGE8, MFG-E8, MFGM, Milk fat globule-EGF factor 8, milk fat globule-EGF factor 8 protein, O-acetyl disialoganglioside synthase, OAcGD3S, SED1, SPAG10, sperm associated antigen 10, sperm surface protein hP47
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.