product summary
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company name :
R&D Systems
product type :
ELISA/assay
product name :
Mouse CXCL4/PF4 Quantikine ELISA Kit
catalog :
MCX400
quantity :
1 Kit
price :
655 USD
more info or order :
R&D Systems product webpage
citations: 9
Reference
Gaur K, Asuru T, Srivastava M, Singh N, Purushotham N, Poojary B, et al. 7D, a small molecule inhibits dengue infection by increasing interferons and neutralizing-antibodies via CXCL4:CXCR3:p38:IRF3 and Sirt1:STAT3 axes respectively. EMBO Mol Med. 2024;16:2376-2401 pubmed publisher
Luis T, Barkas N, Carrelha J, Giustacchini A, Mazzi S, Norfo R, et al. Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner. Nat Commun. 2023;14:6062 pubmed publisher
Schroer A, Ventura P, Sucharov J, Misra R, Chui M, Bieri G, et al. Platelet factors attenuate inflammation and rescue cognition in ageing. Nature. 2023;620:1071-1079 pubmed publisher
Graça F, Stephan A, Minden Birkenmaier B, Shirinifard A, Wang Y, Demontis F, et al. Platelet-derived chemokines promote skeletal muscle regeneration by guiding neutrophil recruitment to injured muscles. Nat Commun. 2023;14:2900 pubmed publisher
Heazlewood S, Ahmad T, Cao B, Cao H, Domingues M, Sun X, et al. High ploidy large cytoplasmic megakaryocytes are hematopoietic stem cells regulators and essential for platelet production. Nat Commun. 2023;14:2099 pubmed publisher
Joseph R, Soundararajan R, Vasaikar S, Yang F, Allton K, Tian L, et al. CD8+ T cells inhibit metastasis and CXCL4 regulates its function. Br J Cancer. 2021;125:176-189 pubmed publisher
Lu W, Jia D, An S, Mu M, Qiao X, Liu Y, et al. Calf Spleen Extractive Injection protects mice against cyclophosphamide-induced hematopoietic injury through G-CSF-mediated JAK2/STAT3 signaling. Sci Rep. 2017;7:8402 pubmed publisher
Zhi H, Dai J, Liu J, Zhu J, Newman D, Gao C, et al. Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase. PLoS ONE. 2015;10:e0135738 pubmed publisher
Zheng Y, Adams T, Zhi H, Yu M, Wen R, Newman P, et al. Restoration of responsiveness of phospholipase Cγ2-deficient platelets by enforced expression of phospholipase Cγ1. PLoS ONE. 2015;10:e0119739 pubmed publisher
image
image 1 :
R&D Systems MCX400 image 1
Mouse CXCL4/PF4 ELISA Standard Curve
product information
master code :
MCX400
SKU :
MCX400
product name :
Mouse CXCL4/PF4 Quantikine ELISA Kit
unit size :
1 Kit
description :
The Mouse CXCL4/PF4 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies mouse CXCL4/PF4 in cell culture supernates (50 ul), serum (10 ul), platelet-poor edta plasma (10 ul), platelet-poor heparin plasma (10 ul).
target :
CXCL4/PF4
category :
ELISAs
species :
Mouse
specificity :
Natural and recombinant mouse PF4
gene symbol :
Pf4
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Serum (10 uL), Platelet-poor EDTA Plasma (10 uL), Platelet-poor Heparin Plasma (10 uL)
elisaSensitivity :
0.01 ng/mL
elisaRange :
0.08 - 5 ng/mL
top caption :
Mouse CXCL4/PF4 ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Mouse PF4 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse PF4 in cell culture supernates, serum, and platelet-poor plasma. It contains E. coli -expressed recombinant mouse PF4 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant factor accurately. Results obtained using natural mouse PF4 showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse PF4.
alt names :
chemokine (C-X-C motif) ligand 4, C-X-C motif chemokine 4, CXCL4iroplact, Iroplact, MGC138298, Oncostatin-A, PF4, PF-4, platelet factor 4, SCYB4oncostatin-A
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.