Mouse CX3CL1/Fractalkine Quantikine ELISA Kit | R&D Systems MCX310 product information

product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Mouse CX3CL1/Fractalkine Quantikine ELISA Kit

catalog :

MCX310

quantity :

1 Kit

price :

655 USD

more info or order :

R&D Systems product webpage

citations: 12

Reference
Gupta N, Somayajulu M, Gurdziel K, LoGrasso G, Aziz H, Rosati R, et al. The miR-183/96/182 cluster regulates sensory innervation, resident myeloid cells and functions of the cornea through cell type-specific target genes. Sci Rep. 2024;14:7676 pubmed publisher
Inoue K, Morimoto H, Ohgidani M, Ueki T. Modulation of inflammatory responses by fractalkine signaling in microglia. PLoS ONE. 2021;16:e0252118 pubmed publisher
Helmke A, Hüsing A, Gaedcke S, Brauns N, Balzer M, Reinhardt M, et al. Peritoneal dialysate-range hypertonic glucose promotes T-cell IL-17 production that induces mesothelial inflammation. Eur J Immunol. 2021;51:354-367 pubmed publisher
Fu R, Guo H, Janga S, Choi M, Klinngam W, Edman M, et al. Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren's syndrome murine model. Sci Rep. 2020;10:1455 pubmed publisher
Dorfman M, Krull J, Douglass J, Fasnacht R, Lara Lince F, Meek T, et al. Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice. Nat Commun. 2017;8:14556 pubmed publisher
He Z, Hua J, Qian D, Gong J, Lin S, Xu C, et al. Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-α Stimulated Gene/Protein 6. Sci Rep. 2016;6:38438 pubmed publisher
Reed J, Stone M, Beadnell T, Ryu Y, Griffin T, Schwertfeger K. Fibroblast growth factor receptor 1 activation in mammary tumor cells promotes macrophage recruitment in a CX3CL1-dependent manner. PLoS ONE. 2012;7:e45877 pubmed publisher
Tighe R, Li Z, Potts E, Frush S, Liu N, Gunn M, et al. Ozone inhalation promotes CX3CR1-dependent maturation of resident lung macrophages that limit oxidative stress and inflammation. J Immunol. 2011;187:4800-8 pubmed publisher
Ishida Y, Hayashi T, Goto T, Kimura A, Akimoto S, Mukaida N, et al. Essential involvement of CX3CR1-mediated signals in the bactericidal host defense during septic peritonitis. J Immunol. 2008;181:4208-18 pubmed
Trujillo G, O Connor E, Kunkel S, Hogaboam C. A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis. Am J Pathol. 2008;172:1209-21 pubmed publisher
Ren T, Chen Q, Tian Z, Wei H. Down-regulation of surface fractalkine by RNA interference in B16 melanoma reduced tumor growth in mice. Biochem Biophys Res Commun. 2007;364:978-84 pubmed
Laragione T, Yarlett N, Brenner M, Mello A, Sherry B, Miller E, et al. The arthritis severity quantitative trait loci Cia4 and Cia6 regulate neutrophil migration into inflammatory sites and levels of TNF-alpha and nitric oxide. J Immunol. 2007;178:2344-51 pubmed

image

image 1 :

Mouse CX3CL1/Fractalkine ELISA Standard Curve

product information

master code :

MCX310

SKU :

MCX310

product name :

Mouse CX3CL1/Fractalkine Quantikine ELISA Kit

unit size :

1 Kit

description :

The Mouse CX3CL1/Fractalkine Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies mouse CX3CL1/Fractalkine in cell culture supernates (50 ul), tissue homogenates (50 ul), serum (50 ul), edta plasma (50 ul), heparin plasma (50 ul).

target :

CX3CL1/Fractalkine

category :

ELISAs

species :

Mouse

specificity :

Natural and recombinant mouse Fractalkine (chemokine and extracellular domains)

gene symbol :

Cx3cl1

kit type :

Solid Phase Sandwich ELISA

assay length :

4.5 hours

elisaSampleTypes :

Cell Culture Supernates (50 uL), Tissue Homogenates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL)

elisaSensitivity :

0.32 ng/mL

elisaRange :

0.62 - 40 ng/mL

top caption :

Mouse CX3CL1/Fractalkine ELISA Standard Curve

applications :

ELISA

USD :

655 USD

product details :

The Quantikine Mouse Fractalkine Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse Fractalkine in cell culture supernates, tissue homogenates, mouse serum, and plasma. It contains E. coli -expressed recombinant mouse Fractalkine chemokine domain and antibodies raised against the recombinant protein. Results obtained for naturally occurring soluble mouse Fractalkine containing the chemokine domain and the mucin stalk domain showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse Fractalkine.

alt names :

ABCD-3, C3Xkine, chemokine (C-X3-C motif) ligand 1, CX3C membrane-anchored chemokine, CXC3, CXC3C, FKN, fractalkine, Neurotactin, neurotactin), NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, NTTSmall-inducible cytokine D1, SCYD1C-X3-C motif chemokine 1, small inducible cytokine subfamily D (Cys-X3-Cys), member-1

storage :

Store the unopened product at 2 - 8 ░C. Do not use past expiration date.

more info or order :

R&D Systems product webpage