This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Mouse SCF Quantikine ELISA Kit
catalog :
MCK00
quantity :
1 Kit
price :
655 USD
citations: 27
Reference
Takeishi S, Marchand T, Koba W, Borger D, Xu C, Guha C, et al. Haematopoietic stem cell numbers are not solely determined by niche availability. bioRxiv. 2023;: pubmed publisher
Molfetta R, Lecce M, Milito N, Putro E, Pietropaolo G, Marangio C, et al. SCF and IL-33 regulate mouse mast cell phenotypic and functional plasticity supporting a pro-inflammatory microenvironment. Cell Death Dis. 2023;14:616 pubmed publisher
Lee H, Lee J, Yang M, Kim Y, Hong S, Kim J, et al. Endothelial cell-derived stem cell factor promotes lipid accumulation through c-Kit-mediated increase of lipogenic enzymes in brown adipocytes. Nat Commun. 2023;14:2754 pubmed publisher
Heazlewood S, Ahmad T, Cao B, Cao H, Domingues M, Sun X, et al. High ploidy large cytoplasmic megakaryocytes are hematopoietic stem cells regulators and essential for platelet production. Nat Commun. 2023;14:2099 pubmed publisher
Shah M, Kumar H, Qiu S, Li H, Harris M, He J, et al. Low c-Kit expression identifies primitive, therapy-resistant CML stem cells. JCI Insight. 2023;8: pubmed publisher
Huang J, Chen S, Chang W, Hung W, Wu P, Wu L, et al. KITLG Promotes Glomerular Endothelial Cell Injury in Diabetic Nephropathy by an Autocrine Effect. Int J Mol Sci. 2022;23: pubmed publisher
Omatsu Y, Aiba S, Maeta T, Higaki K, Aoki K, Watanabe H, et al. Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells. Nat Commun. 2022;13:2654 pubmed publisher
Foster B, Langsten K, Mansour A, Shi L, Kerr B. Tissue distribution of stem cell factor in adults. Exp Mol Pathol. 2021;122:104678 pubmed publisher
Hastreiter A, Dos Santos G, Makiyama E, Santos E, Borelli P, Fock R. Effects of protein malnutrition on hematopoietic regulatory activity of bone marrow mesenchymal stem cells. J Nutr Biochem. 2021;93:108626 pubmed publisher
Sinha S, Biswas M, Chatterjee S, Kumar S, Sengupta A. Pbrm1 Steers Mesenchymal Stromal Cell Osteolineage Differentiation by Integrating PBAF-Dependent Chromatin Remodeling and BMP/TGF-β Signaling. Cell Rep. 2020;31:107570 pubmed publisher
Fonseca W, Rasky A, Ptaschinski C, Morris S, Best S, Phillips M, et al. Group 2 innate lymphoid cells (ILC2) are regulated by stem cell factor during chronic asthmatic disease. Mucosal Immunol. 2019;12:445-456 pubmed publisher
Mastri M, Lee C, Tracz A, Kerbel R, Dolan M, Shi Y, et al. Tumor-Independent Host Secretomes Induced By Angiogenesis and Immune-Checkpoint Inhibitors. Mol Cancer Ther. 2018;17:1602-1612 pubmed publisher
Bertin E, Piccoli M, Franzin C, Spiro G, Dona S, Dedja A, et al. First steps to define murine amniotic fluid stem cell microenvironment. Sci Rep. 2016;6:37080 pubmed publisher
Cunha M, Lima F, Vinolo M, Hastreiter A, Curi R, Borelli P, et al. Protein malnutrition induces bone marrow mesenchymal stem cells commitment to adipogenic differentiation leading to hematopoietic failure. PLoS ONE. 2013;8:e58872 pubmed publisher
Arcangeli M, Frontera V, Bardin F, Obrados E, Adams S, Chabannon C, et al. JAM-B regulates maintenance of hematopoietic stem cells in the bone marrow. Blood. 2011;118:4609-19 pubmed publisher
Horiuchi K, Morioka H, Takaishi H, Akiyama H, Blobel C, Toyama Y. Ectodomain shedding of FLT3 ligand is mediated by TNF-alpha converting enzyme. J Immunol. 2009;182:7408-14 pubmed publisher
Suh H, Ji M, Gooya J, Lee M, Klarmann K, Keller J. Cell-nonautonomous function of Id1 in the hematopoietic progenitor cell niche. Blood. 2009;114:1186-95 pubmed publisher
Schroeter M, Humboldt T, Schafer K, Konstantinides S. Rosuvastatin reduces atherosclerotic lesions and promotes progenitor cell mobilisation and recruitment in apolipoprotein E knockout mice. Atherosclerosis. 2009;205:63-73 pubmed publisher
Higuchi K, Ayach B, Sato T, Chen M, Devine S, Rasaiah V, et al. Direct injection of kit ligand-2 lentivirus improves cardiac repair and rescues mice post-myocardial infarction. Mol Ther. 2009;17:262-8 pubmed publisher
Huang B, Lei Z, Zhang G, Li D, Song C, Li B, et al. SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment. Blood. 2008;112:1269-79 pubmed publisher
Zhang P, Nelson S, Bagby G, Siggins R, Shellito J, Welsh D. The lineage-c-Kit+Sca-1+ cell response to Escherichia coli bacteremia in Balb/c mice. Stem Cells. 2008;26:1778-86 pubmed publisher
Ebos J, Lee C, Christensen J, Mutsaers A, Kerbel R. Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy. Proc Natl Acad Sci U S A. 2007;104:17069-74 pubmed
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Wang C, Verma S, Hsieh I, Chen Y, Kuo L, Yang N, et al. Enalapril increases ischemia-induced endothelial progenitor cell mobilization through manipulation of the CD26 system. J Mol Cell Cardiol. 2006;41:34-43 pubmed
Liao H, Chen Y, Yang Y. A novel polysaccharide of black soybean promotes myelopoiesis and reconstitutes bone marrow after 5-flurouracil- and irradiation-induced myelosuppression. Life Sci. 2005;77:400-13 pubmed
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product information
master code :
MCK00
SKU :
MCK00
product name :
Mouse SCF Quantikine ELISA Kit
unit size :
1 Kit
description :
The Mouse SCF Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies mouse SCF/c-kit Ligand in cell culture supernates (50 ul), serum (25 ul), edta plasma (25 ul).
target :
SCF/c-kit Ligand
category :
ELISAs
species :
Mouse
specificity :
Natural and recombinant mouse SCF
gene symbol :
Kitl
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Serum (25 uL), EDTA Plasma (25 uL)
elisaSensitivity :
5 pg/mL
elisaRange :
31.20 - 2000 pg/mL
top caption :
Mouse SCF/c-kit Ligand ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Mouse SCF Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse SCF levels in cell culture supernates, serum, and EDTA plasma. It contains E. coli -expressed recombinant mouse SCF and antibodies raised against the recombinant protein. Results obtained for naturally occurring mouse SCF showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of natural mouse SCF.
alt names :
c-kit Ligand, DCUA, DFNA69, DKFZp686F2250, familial progressive hyperpigmentation 2, FPH2, FPHH, KIT ligand, Kitl, KITLG, KL-1, Mast cell growth factor, MGF, MGFSHEP7, SCFStem cell factor, SFc-Kit ligand, SHEP7, SLF, steel factor
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.