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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Mouse/Rat PDGF-BB Quantikine ELISA Kit
catalog :
MBB00
quantity :
1 Kit
price :
655 USD
citations: 22
Reference
Abu Helal R, Muturi H, Lee A, Li W, Ghadieh H, Najjar S. Aortic Fibrosis in Insulin-Sensitive Mice with Endothelial Cell-Specific Deletion of Ceacam1 Gene. Int J Mol Sci. 2022;23: pubmed publisher
Feng Y, Yang X, Huang J, Shen M, Wang L, Chen X, et al. Pharmacological Inhibition of Glutaminase 1 Attenuates Alkali-Induced Corneal Neovascularization by Modulating Macrophages. Oxid Med Cell Longev. 2022;2022:1106313 pubmed publisher
Tillie R, Theelen T, van Kuijk K, Temmerman L, de Bruijn J, Gijbels M, et al. A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis. Cells. 2021;10: pubmed publisher
Isozaki S, Konishi H, Fujiya M, Tanaka H, Murakami Y, Kashima S, et al. Probiotic-Derived Polyphosphate Accelerates Intestinal Epithelia Wound Healing through Inducing Platelet-Derived Mediators. Mediators Inflamm. 2021;2021:5582943 pubmed publisher
Yu Y, Dai K, Gao Z, Tang W, Shen T, Yuan Y, et al. Sulfated polysaccharide directs therapeutic angiogenesis via endogenous VEGF secretion of macrophages. Sci Adv. 2021;7: pubmed publisher
El Bakly W, Medhat M, Shafei M, Tash R, ElRefai M, Shoukry Y, et al. Optimized platelet rich plasma releasate (O-rPRP) repairs galactosemia-induced ovarian follicular loss in rats by activating mTOR signaling and inhibiting apoptosis. Heliyon. 2020;6:e05006 pubmed publisher
Hosaka K, Yang Y, Seki T, Du Q, Jing X, He X, et al. Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors. Nat Commun. 2020;11:3704 pubmed publisher
Poh K, Lee P, Djohan A, Galupo M, Songco G, Yeo T, et al. Transplantation of Endothelial Progenitor Cells in Obese Diabetic Rats Following Myocardial Infarction: Role of Thymosin Beta-4. Cells. 2020;9: pubmed publisher
Kuo T, Cheng K, Shan Y, Chen L, Hung W. β-catenin-activated autocrine PDGF/Src signaling is a therapeutic target in pancreatic cancer. Theranostics. 2019;9:324-336 pubmed publisher
Zhou X, Franklin R, Adler M, JACOX J, Bailis W, Shyer J, et al. Circuit Design Features of a Stable Two-Cell System. Cell. 2018;172:744-757.e17 pubmed publisher
El Lakkany N, El Maadawy W, Seif El Din S, Hammam O, Mohamed S, Ezzat S, et al. Rosmarinic acid attenuates hepatic fibrogenesis via suppression of hepatic stellate cell activation/proliferation and induction of apoptosis. Asian Pac J Trop Med. 2017;10:444-453 pubmed publisher
Urello M, Kiick K, Sullivan M. Integration of growth factor gene delivery with collagen-triggered wound repair cascades using collagen-mimetic peptides. Bioeng Transl Med. 2016;1:207-219 pubmed
Shiga Y, Orita S, Kubota G, Kamoda H, Yamashita M, Matsuura Y, et al. Freeze-Dried Platelet-Rich Plasma Accelerates Bone Union with Adequate Rigidity in Posterolateral Lumbar Fusion Surgery Model in Rats. Sci Rep. 2016;6:36715 pubmed publisher
Ueno K, Takeuchi Y, Samura M, Tanaka Y, Nakamura T, Nishimoto A, et al. Treatment of refractory cutaneous ulcers with mixed sheets consisting of peripheral blood mononuclear cells and fibroblasts. Sci Rep. 2016;6:28538 pubmed publisher
Yang Y, Andersson P, Hosaka K, Zhang Y, Cao R, Iwamoto H, et al. The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages. Nat Commun. 2016;7:11385 pubmed publisher
Re S, Giordano G, Yakoub Y, Devosse R, Uwambayinema F, Couillin I, et al. Uncoupling between inflammatory and fibrotic responses to silica: evidence from MyD88 knockout mice. PLoS ONE. 2014;9:e99383 pubmed publisher
Glinskii O, Huxley V, Glinskii V, Rubin L, Glinsky V. Pulsed estrogen therapy prevents post-OVX porcine dura mater microvascular network weakening via a PDGF-BB-dependent mechanism. PLoS ONE. 2013;8:e82900 pubmed publisher
Ma W, Han W, Greer P, Tuder R, Toque H, Wang K, et al. Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease. J Clin Invest. 2011;121:4548-66 pubmed publisher
Fujii T, Onimaru M, Yonemitsu Y, Kuwano H, Sueishi K. Statins restore ischemic limb blood flow in diabetic microangiopathy via eNOS/NO upregulation but not via PDGF-BB expression. Am J Physiol Heart Circ Physiol. 2008;294:H2785-91 pubmed publisher
He M, Kubo H, Ishizawa K, Hegab A, Yamamoto Y, Yamamoto H, et al. The role of the receptor for advanced glycation end-products in lung fibrosis. Am J Physiol Lung Cell Mol Physiol. 2007;293:L1427-36 pubmed
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Koyanagi T, Noguchi K, Ootani A, Inagaki K, Robbins R, Mochly Rosen D. Pharmacological inhibition of epsilon PKC suppresses chronic inflammation in murine cardiac transplantation model. J Mol Cell Cardiol. 2007;43:517-22 pubmed
product information
master code :
MBB00
SKU :
MBB00
product name :
Mouse/Rat PDGF-BB Quantikine ELISA Kit
unit size :
1 Kit
description :
The Mouse/Rat PDGF-BB Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies mouse, rat PDGF-BB in cell culture supernates (50 ul), serum (10 ul), edta plasma (25 ul), heparin plasma (25 ul).
target :
PDGF-BB
category :
ELISAs
species :
Mouse, Rat
specificity :
Natural and recombinant mouse and rat PDGF-BB. This assay cross-reacts 10.2% with recombinant Rat PDGF-AB, 5.3% with recombinant Human PDGF-AB, 64.7% with recombinant Human PDGF-BB, 38.1% with natural Human PDGF and 65.2% with natural Porcine PDGF.
gene symbol :
Pdgfb
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Serum (10 uL), EDTA Plasma (25 uL), Heparin Plasma (25 uL)
elisaSensitivity :
19.3 pg/mL
elisaRange :
31.20 - 2000 pg/mL
top caption :
Mouse/Rat PDGF-BB ELISA Cell Culture Supernate Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Mouse/Rat PDGF-BB Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse/rat PDGF-BB in cell culture supernates, serum, and plasma. It contains E. coli -expressed recombinant rat PDGF-BB and antibodies raised against recombinant human PDGF-BB. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural mouse/rat PDGF-BB showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring mouse/rat PDGF-BB.
alt names :
c-sis;IBGC5;PDGF2;PDGF-2;PDGFB;Platelet-derived growth factor subunit B;SIS;SSV, PDGFBB
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.