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product summary
company name :
R&D Systems
product type :
ELISA/assay
product name :
Mouse/Rat Angiopoietin-2 Quantikine ELISA Kit
catalog :
MANG20
quantity :
1 Kit
price :
655 USD
citations: 25
Reference
Wang L, Lin B, Zhai M, Hull L, Cui W, Xiao M. Endothelial Dysfunction and Impaired Wound Healing Following Radiation Combined Skin Wound Injury. Int J Mol Sci. 2024;25: pubmed publisher
Tian R, Li R, Chen Y, Liu D, Li Y, He S, et al. Shenfu injection ameliorates endotoxemia-associated endothelial dysfunction and organ injury via inhibiting PI3K/Akt-mediated glycolysis. J Ethnopharmacol. 2024;335:118634 pubmed publisher
Meder L, Orschel C, Otto C, Koker M, Br xe4 gelmann J, Ercanoglu M, et al. Blocking the angiopoietin-2-dependent integrin β-1 signaling axis abrogates small cell lung cancer invasion and metastasis. JCI Insight. 2024;9: pubmed publisher
Allam R, El Kerdawy A, Gouda A, Ahmed K, Abdel Mohsen H. Benzimidazole-oxindole hybrids as multi-kinase inhibitors targeting melanoma. Bioorg Chem. 2024;146:107243 pubmed publisher
van Leeuwen A, Beijer E, Ibelings R, Dekker N, van der Steen M, Roelofs J, et al. Female sex protects against renal edema, but not lung edema, in mice with partial deletion of the endothelial barrier regulator Tie2 compared to male sex. PLoS ONE. 2023;18:e0293673 pubmed publisher
Wideman S, Frost J, Richter F, Naylor C, Lopes J, Viveiros N, et al. Cellular iron governs the host response to malaria. PLoS Pathog. 2023;19:e1011679 pubmed publisher
Lin Y, McClennan A, Hoffman L. Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice. Biomedicines. 2023;11: pubmed publisher
Atreya M, Cvijanovich N, Fitzgerald J, Weiss S, Bigham M, Jain P, et al. Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1. Res Sq. 2023;: pubmed publisher
Himmels P, Nguyen T, Mitzner M, Arrazate A, Yeung S, Burton J, et al. T cell-dependent bispecific antibodies alter organ-specific endothelial cell-T cell interaction. EMBO Rep. 2023;24:e55532 pubmed publisher
Karabid N, Wiedemann T, Gulde S, Mohr H, Segaran R, Geppert J, et al. Angpt2/Tie2 autostimulatory loop controls tumorigenesis. EMBO Mol Med. 2022;14:e14364 pubmed publisher
Tran V, Weckman A, Crowley V, Cahill L, Zhong K, Cabrera A, et al. The Angiopoietin-Tie2 axis contributes to placental vascular disruption and adverse birth outcomes in malaria in pregnancy. EBioMedicine. 2021;73:103683 pubmed publisher
Bogatcheva N, Coleman M. Concentrated Secretome of Adipose Stromal Cells Limits Influenza A Virus-Induced Lung Injury in Mice. Cells. 2021;10: pubmed publisher
Nahrendorf W, Ivens A, Spence P. Inducible mechanisms of disease tolerance provide an alternative strategy of acquired immunity to malaria. elife. 2021;10: pubmed publisher
Zhang T, Shibamoto T, Tanida M, Taniguchi M, Kuda Y, Yang W, et al. Angiopoietin-2 is released during anaphylactic hypotension in anesthetized and unanesthetized rats. PLoS ONE. 2020;15:e0242026 pubmed publisher
Cornelius D, Travis O, Tramel R, Borges Rodriguez M, Baik C, Greer M, et al. NLRP3 inflammasome inhibition attenuates sepsis-induced platelet activation and prevents multi-organ injury in cecal-ligation puncture. PLoS ONE. 2020;15:e0234039 pubmed publisher
Bae H, Hong K, Lee C, Jang C, Lee S, Choe K, et al. Angiopoietin-2-integrin α5β1 signaling enhances vascular fatty acid transport and prevents ectopic lipid-induced insulin resistance. Nat Commun. 2020;11:2980 pubmed publisher
Wolf A, Herb M, Schramm M, Langmann T. The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye. Nat Commun. 2020;11:2709 pubmed publisher
Li Z, Korhonen E, Merlini A, Strauss J, Wihuri E, Nurmi H, et al. Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS. J Clin Invest. 2020;130:1977-1990 pubmed publisher
Zhang J, Li S, Zhang S, Wang Y, Jin S, Zhao C, et al. Effect of Icariside II and Metformin on Penile Erectile Function, Histological Structure, Mitochondrial Autophagy, Glucose-Lipid Metabolism, Angiotensin II and Sex Hormone in Type 2 Diabetic Rats With Erectile Dysfunction. Sex Med. 2020;8:168-177 pubmed publisher
Pedrosa A, Bodrug N, Gómez Escudero J, Carter E, Reynolds L, Georgiou P, et al. Tumor angiogenesis is differentially regulated by phosphorylation of endothelial cell focal adhesion kinase tyrosines-397 and -861. Cancer Res. 2019;: pubmed publisher
Cornelius D, Baik C, Travis O, White D, Young C, Austin Pierce W, et al. NLRP3 inflammasome activation in platelets in response to sepsis. Physiol Rep. 2019;7:e14073 pubmed publisher
Kim J, Park J, Choi J, Park I, Hwang Y, Bae H, et al. Tie2 activation promotes choriocapillary regeneration for alleviating neovascular age-related macular degeneration. Sci Adv. 2019;5:eaau6732 pubmed publisher
Kim B, Jang C, Dharaneeswaran H, Li J, Bhide M, Yang S, et al. Endothelial pyruvate kinase M2 maintains vascular integrity. J Clin Invest. 2018;128:4543-4556 pubmed publisher
Crowley V, Ayi K, Lu Z, Liby K, Sporn M, Kain K. Synthetic oleanane triterpenoids enhance blood brain barrier integrity and improve survival in experimental cerebral malaria. Malar J. 2017;16:463 pubmed publisher
Jenny Zhou H, Qin L, Zhang H, Tang W, Ji W, He Y, et al. Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med. 2016;22:1033-1042 pubmed publisher
product information
master code :
MANG20
SKU :
MANG20
product name :
Mouse/Rat Angiopoietin-2 Quantikine ELISA Kit
unit size :
1 Kit
description :
The Mouse/Rat Angiopoietin-2 Quantikine ELISA Kit from R&D Systems is a Solid Phase Sandwich ELISA that quantifies mouse, rat Angiopoietin-2 in cell culture supernates (50 ul), tissue lysates (10 ul), serum (10 ul), edta plasma (10 ul), heparin plasma (10 ul).
target :
Angiopoietin-2
category :
ELISAs
species :
Mouse, Rat
specificity :
Natural and recombinant mouse and rat Angiopoietin-2.
gene symbol :
Angpt2
kit type :
Solid Phase Sandwich ELISA
assay length :
4.5 hours
elisaSampleTypes :
Cell Culture Supernates (50 uL), Tissue Lysates (10 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL)
elisaSensitivity :
4.98 pg/mL
elisaRange :
39.10 - 2500 pg/mL
top caption :
Mouse/Rat Angiopoietin-2 ELISA Standard Curve
applications :
ELISA
USD :
655 USD
product details :
The Quantikine Mouse/Rat Angiopoietin-2 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse and rat Angiopoietin-2 in cell culture supernates, tissue lysates, serum, and plasma. It contains CHO cell-expressed recombinant mouse Angiopoietin-2 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant factor accurately. Results obtained using natural Angiopoietin-2 showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural Angiopoietin-2.
alt names :
AGPT2, ANG2, ANG-2, angiopoietin 2, angiopoietin-2, angiopoietin-2a, angiopoietin-2B, angiopoitin 2, ANGPT2, Tie2-ligand
storage :
Store the unopened product at 2 - 8 ░C. Do not use past expiration date.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.