Human PSGL-1/CD162 Antibody | R&D Systems MAB996 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human PSGL-1/CD162 Antibody

catalog :

MAB996

quantity :

500 ug (also 25 ug)

price :

549 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CHO131

reactivity :

human, mouse

application :

neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 3

Reference
Sun C, Feng S, Cao Z, Bei J, Chen Q, Zhao W, et al. Up-Regulated Expression of Matrix Metalloproteinases in Endothelial Cells Mediates Platelet Microvesicle-Induced Angiogenesis. Cell Physiol Biochem. 2017;41:2319-2332 pubmed publisher
Banks J, Herman C, Bailey R. Bromelain decreases neutrophil interactions with P-selectin, but not E-selectin, in vitro by proteolytic cleavage of P-selectin glycoprotein ligand-1. PLoS ONE. 2013;8:e78988 pubmed publisher
Santen S, Schramm R, Menger M, Wang Y, Jeppsson B, Thorlacius H. P-selectin glycoprotein ligand-1 regulates chemokine-dependent leukocyte recruitment in colonic ischemia-reperfusion. Inflamm Res. 2007;56:452-8 pubmed

product information

master code :

MAB996

SKU :

MAB996

product name :

Human PSGL-1/CD162 Antibody

unit size :

500 ug (also 25 ug)

description :

The Human PSGL-1/CD162 Antibody from R&D Systems is a mouse monoclonal antibody to PSGL-1/CD162. This antibody reacts with human,mouse. The Human PSGL-1/CD162 Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Adhesion Blockade,CyTOF-ready.

target :

PSGL-1/CD162

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

CHO131

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

CHO Chinese hamster ovary cell line transfected with human PSGL-1/CD162

isotype :

IgM

purity :

IgM-specific Affinity-purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human PSGL-1/CD162. Recognizes sLex-bearing core 2 O-glycan stuctures. It does not recognize sLex on an extended core 1 O-glycan. The sLex-bearing, core 2 O-glycan structure decorates the P-Selectin ligand PSGL-1, and the presence of this glycan structure is required for high affinity P-Selectin binding (1). This antibody stains human and canine leukocytes but does not recognize monkey, mouse, rabbit, porcine, feline or bovine leukocytes.

gene symbol :

SELPLG

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Human PSGL-1/CD162 by Flow Cytometry

applications :

Flow Cytometry,Neutralization,Adhesion Blockade,CyTOF-ready

USD :

549 USD

alt names :

CD162, CD162 antigen, P-selectin glycoprotein ligand 1, PSGL1, PSGL-1cutaneous lymphocyte-associated associated antigen, selectin P ligandCLA, SELPLG

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage