Mouse Amphiregulin Antibody | R&D Systems MAB989-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Amphiregulin Antibody

catalog :

MAB989-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

206220

reactivity :

human, mouse

application :

western blot, neutralization, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 7

Reference
Uddin M, Thompson B, Leslie J, Fishman C, Sol Church K, Kumar P, et al. Investigating the impact of antibiotic-induced dysbiosis on protection from Clostridium difficile colitis by mouse colonic innate lymphoid cells. MBio. 2024;15:e0333823 pubmed publisher
Sun R, Zhao H, Gao D, Ni A, Li H, Chen L, et al. Amphiregulin couples IL1RL1+ regulatory T cells and cancer-associated fibroblasts to impede antitumor immunity. Sci Adv. 2023;9:eadd7399 pubmed publisher
Schnell A, Huang L, Singer M, Singaraju A, Barilla R, Regan B, et al. Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity. Cell. 2021;184:6281-6298.e23 pubmed publisher
Ko J, Kim H, Jeong H, Lee H, Oh J. Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis. Cell Rep. 2020;30:3806-3820.e6 pubmed publisher
Monticelli L, Osborne L, Noti M, Tran S, Zaiss D, Artis D. IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin-EGFR interactions. Proc Natl Acad Sci U S A. 2015;112:10762-7 pubmed publisher
Harada M, Kamimura D, Arima Y, Kohsaka H, Nakatsuji Y, Nishida M, et al. Temporal expression of growth factors triggered by epiregulin regulates inflammation development. J Immunol. 2015;194:1039-46 pubmed publisher
Nautiyal J, Steel J, Mane M, Oduwole O, Poliandri A, Alexi X, et al. The transcriptional co-factor RIP140 regulates mammary gland development by promoting the generation of key mitogenic signals. Development. 2013;140:1079-89 pubmed publisher

product information

master code :

MAB989

SKU :

MAB989-100

product name :

Mouse Amphiregulin Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Mouse Amphiregulin Antibody from R&D Systems is a rat monoclonal antibody to Amphiregulin. This antibody reacts with mouse,transgenic mouse. The Mouse Amphiregulin Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Immunohistochemistry-Paraffin,In vivo assay,Western Blot.

target :

Amphiregulin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

206220

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse Amphiregulin, Ser94-Lys191, Accession # P31955

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse,Transgenic Mouse

specificity :

Detects mouse Amphiregulin in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) Amphiregulin, rhEGF, rhHB-EGF, rhNRG-1 alpha , rhNRG-1┐▀1, rhTGF-alpha , recombinant mouse (rm) BTC, rmEpigen, or rmEpiregulin.

gene symbol :

AREG

accessionNumbers :

P31955

applications :

Flow Cytometry,Neutralization,Immunohistochemistry-Paraffin,In vivo assay,Western Blot

USD :

459 USD

alt names :

amphiregulin, AR, AREG, AREGB, Colorectum cell-derived growth factor, CRDGF, MGC13647, schwannoma-derived growth factor, SDGF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage