Human TIMP-3 Antibody | R&D Systems MAB973-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TIMP-3 Antibody

catalog :

MAB973-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

439 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

183551

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 7

Reference
Varga A, Németh I, Kemeny L, Varga J, Tiszlavicz L, Kumar D, et al. Elevated Serum Gastrin Is Associated with Melanoma Progression: Putative Role in Increased Migration and Invasion of Melanoma Cells. Int J Mol Sci. 2023;24: pubmed publisher
Tonello R, Silveira Prudente A, Hoon Lee S, Faith Cohen C, Xie W, Paranjpe A, et al. Single-cell analysis of dorsal root ganglia reveals metalloproteinase signaling in satellite glial cells and pain. Brain Behav Immun. 2023;113:401-414 pubmed publisher
Hou T, Wu S, Kau H, Tsai C. JNK and p38 Inhibitors Prevent Transforming Growth Factor-β1-Induced Myofibroblast Transdifferentiation in Human Graves' Orbital Fibroblasts. Int J Mol Sci. 2021;22: pubmed publisher
Cassuto J, Folestad A, Göthlin J, Malchau H, Kärrholm J. Concerted actions by MMPs, ADAMTS and serine proteases during remodeling of the cartilage callus into bone during osseointegration of hip implants. Bone Rep. 2020;13:100715 pubmed publisher
Schubert K, Collins L, Green P, Nagase H, Troeberg L. LRP1 Controls TNF Release via the TIMP-3/ADAM17 Axis in Endotoxin-Activated Macrophages. J Immunol. 2019;202:1501-1509 pubmed publisher
Chanalaris A, Doherty C, Marsden B, Bambridge G, Wren S, Nagase H, et al. Suramin Inhibits Osteoarthritic Cartilage Degradation by Increasing Extracellular Levels of Chondroprotective Tissue Inhibitor of Metalloproteinases 3. Mol Pharmacol. 2017;92:459-468 pubmed publisher
Villeneuve J, Block A, Le Bousse Kerdiles M, Lepreux S, Nurden P, Ripoche J, et al. Tissue inhibitors of matrix metalloproteinases in platelets and megakaryocytes: a novel organization for these secreted proteins. Exp Hematol. 2009;37:849-56 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB973

SKU :

MAB973-100

product name :

Human TIMP-3 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human TIMP-3 Antibody from R&D Systems is a mouse monoclonal antibody to TIMP-3. This antibody reacts with human,mouse. The Human TIMP-3 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Neutralization,ELISA Detection,Immunocytochemistry,Immunoprecipitation,ELISA Capture (Matched Antibody Pair).

target :

TIMP-3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

183551

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Immunohistochemistry 8-25 ug/mL, Immunoprecipitation 25 ug/mL, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TIMP-3, Cys24-Pro211, Accession # P35625

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human TIMP-3 in ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human TIMP-1, -2, or -4 is observed.

gene symbol :

TIMP3

accessionNumbers :

P35625

applications :

Immunoprecipitation,ELISA Capture (Matched Antibody Pair),Immunohistochemistry,Western Blot,Neutralization,Immunocytochemistry,ELISA Detection

USD :

439 USD

alt names :

HSMRK222, K222, K222TA2, metalloproteinase inhibitor 3, MIG-5 protein, Protein MIG-5, pseudoinflammatory), SFD, TIMP metallopeptidase inhibitor 3, TIMP3, TIMP-3, tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, Tissue inhibitor of metalloproteinases 3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage