product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Fibroblast Activation Protein alpha /FAP Antibody
catalog :
MAB9727-100
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
983802
reactivity :
human, mouse
application :
ELISA, immunocytochemistry, flow cytometry
more info or order :
citations: 5
Reference
Downton P, Dickson S, Ray D, Bechtold D, Gibbs J. Fibroblast-like synoviocytes orchestrate daily rhythmic inflammation in arthritis. Open Biol. 2024;14:240089 pubmed publisher
Glabman R, Olkowski C, Minor H, Bassel L, Kedei N, Choyke P, et al. Tumor Suppression by Anti-Fibroblast Activation Protein Near-Infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts. Cancers (Basel). 2024;16: pubmed publisher
Das S, Valton J, Duchateau P, Poirot L. Stromal depletion by TALEN-edited universal hypoimmunogenic FAP-CAR T cells enables infiltration and anti-tumor cytotoxicity of tumor antigen-targeted CAR-T immunotherapy. Front Immunol. 2023;14:1172681 pubmed publisher
Liu J, Wang Y, Mu C, Li M, Li K, Li S, et al. Pancreatic tumor eradication via selective Pin1 inhibition in cancer-associated fibroblasts and T lymphocytes engagement. Nat Commun. 2022;13:4308 pubmed publisher
Wormsbaecher C, Hindman A, Avendano A, Cortes Medina M, Jones C, Bushman A, et al. In utero estrogenic endocrine disruption alters the stroma to increase extracellular matrix density and mammary gland stiffness. Breast Cancer Res. 2020;22:41 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB9727
SKU :
MAB9727-100
product name :
Mouse Fibroblast Activation Protein alpha /FAP Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse Fibroblast Activation Protein alpha /FAP Antibody from R&D Systems is a rat monoclonal antibody to Fibroblast Activation Protein alpha/FAP. This antibody reacts with mouse,transgenic mouse. The Mouse Fibroblast Activation Protein alpha /FAP Antibody has been validated for the following applications: Flow Cytometry,ELISA,Immunocytochemistry.
target :
Fibroblast Activation Protein alpha/FAP
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
983802
conjugate :
Unconjugated
dilution :
Flow Cytometry 0.25 ug/10^6 cells, ELISA, Immunocytochemistry 8-25 ug/mL
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Fibroblast Activation Protein alpha /FAP, Leu26-Asp761, Accession # P97321
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse,Transgenic Mouse
specificity :
Detects mouse Fibroblast Activation Protein alpha /FAP in direct ELISAs.
top caption :
Detection of Fibroblast Activation Protein alpha/FAP antibody in C2C12 Mouse Cell Line antibody by Flow Cytometry.
accessionNumbers :
P97321
applications :
ELISA,Immunocytochemistry,Flow Cytometry
USD :
469 USD
alt names :
170 kDa melanoma membrane-bound gelatinase, DKFZp686G13158, DPPIV, EC 3.4.21.-, FAP, FAPA, Fibroblast activation protein alpha, fibroblast activation protein, alpha, Integral membrane serine protease, seprase, vibronectin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.