product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse Cathepsin B Antibody
catalog :
MAB965
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
173317
reactivity :
human, mouse
application :
western blot, immunocytochemistry
more info or order :
citations: 5
Reference
Stewart T, Hughes K, Stevenson A, Marino N, Ju A, Morehead M, et al. Mammary mechanobiology - investigating roles for mechanically activated ion channels in lactation and involution. J Cell Sci. 2021;134: pubmed publisher
Alarcon Vila C, Baroja Mazo A, de Torre Minguela C, Martinez C, Martinez Garcia J, Martinez Banaclocha H, et al. CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis. elife. 2020;9: pubmed publisher
Shao Q, Yang M, Liang C, Ma L, Zhang W, Jiang Z, et al. C9orf72 and smcr8 mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis. Autophagy. 2019;:1-16 pubmed publisher
Bronger H, Karge A, Dreyer T, Zech D, Kraeft S, Avril S, et al. Induction of cathepsin B by the CXCR3 chemokines CXCL9 and CXCL10 in human breast cancer cells. Oncol Lett. 2017;13:4224-4230 pubmed publisher
Wendt W, Schulten R, Stichel C, Lübbert H. Intra- versus extracellular effects of microglia-derived cysteine proteases in a conditioned medium transfer model. J Neurochem. 2009;110:1931-41 pubmed publisher
product information
master code :
MAB965
SKU :
MAB965
product name :
Human/Mouse Cathepsin B Antibody
unit size :
500 ug (also 25 ug)
description :
The Human/Mouse Cathepsin B Antibody from R&D Systems is a rat monoclonal antibody to Cathepsin B. This antibody reacts with human,mouse. The Human/Mouse Cathepsin B Antibody has been validated for the following applications: Western Blot,Immunocytochemistry.
target :
Cathepsin B
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
173317
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Cathepsin B, His18-Phe339, Accession # P10605
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects the pro and active forms of human and mouse Cathepsin B in direct ELISAs and Western blots. Does not cross-react with recombinant human Cathepsin C, L, L2, O, S, Z, recombinant mouse Cathepsin C, H, L, or Z.
gene symbol :
CTSB
accessionNumbers :
P10605
applications :
Western Blot,Immunocytochemistry
USD :
559 USD
alt names :
APP secretase, APPS, cathepsin B, Cathepsin B1, CPSBamyloid precursor protein secretase, CTSB, cysteine protease, EC 3.4.22, EC 3.4.22.1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.